Guiding film and preparation method thereof
A technology of guiding film and positioning part, applied in the field of oral cavity, can solve the problems of slow repair speed and single function of biofilm, and achieve the effect of good positioning, speeding up repair speed, good material toughness and strength
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Embodiment 1
[0029] A guide film, the guide film is made of pure titanium, and the guide film includes a main body, a channel, a positioning part and a fixing part, the channel is used for liquid to pass through, the positioning part is used for positioning relative positions, the The fixing part is used to cooperate with the positioning structure to realize positioning; the main body has a composite coating of polydopamine-anticoagulant substance and biologically active substance, and the anticoagulant substance is antithrombin;
[0030] The bioactive substance includes a small molecule bioactive substance, which is minocycline.
Embodiment 2
[0032] A guide film, the guide film is made of titanium alloy, and the titanium content of the guide film is 65%. The guide film includes a main body, a channel, a positioning part and a fixing part, the channel is used for liquid to pass through, the positioning part is used to realize relative position positioning, and the fixing part is used to cooperate with the positioning structure to realize positioning; The main body has a composite coating of polydopamine-anticoagulant substance and bioactive substance, and the anticoagulant substance is heparin; the bioactive substance includes small molecular bioactive substance, which is dexamethasone.
Embodiment 3
[0034]A guide film, the guide film is made of pure titanium. The guide film includes a main body, a channel, a positioning part and a fixing part, the channel is used for liquid to pass through, the positioning part is used for positioning relative positions, and the fixing part is used to cooperate with the positioning structure to realize positioning; the The main body has a composite coating of polydopamine-anticoagulant substances and bioactive substances, and also includes fibronectin, which is used to connect the polydopamine and the anticoagulant substances, and the anticoagulant substances include antithrombin, heparin cofactor- II. Thrombin regulatory protein, protein C; the biologically active substances include small molecular biologically active substances, which are small molecular peptides, and the small molecular peptides are Arg-Gly-Asp peptides and collagen mimic peptides.
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