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Application of traditional Chinese medicine composition in treating fatty liver

A composition and technology of traditional Chinese medicine, which are applied in the field of traditional Chinese medicine composition in the field of preparing and treating or improving fatty liver drugs, can solve the problems of malnutrition, easy accumulation of fat in liver cells, etc., and achieve the effects of improving lipid metabolism disorder and enhancing antioxidant enzyme activity.

Pending Publication Date: 2022-05-06
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 4) Malnutrition, protein deficiency caused by malnutrition is an important cause of fatty liver. It is more common in insufficient food intake or digestive disorders, unable to synthesize apolipoprotein, so that triglycerides accumulate in the liver, forming fatty liver
[0010] 8) Others. Fatty liver can also occur in tuberculosis, bacterial pneumonia, sepsis and other infections. If patients with viral hepatitis restrict their activities excessively and consume a high-sugar and high-calorie diet, liver cell fat is easy to accumulate; receive corticosteroid treatment Fatty liver is more likely to occur after

Method used

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  • Application of traditional Chinese medicine composition in treating fatty liver
  • Application of traditional Chinese medicine composition in treating fatty liver
  • Application of traditional Chinese medicine composition in treating fatty liver

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Example 1 Commercially available Shouhui laxative capsules

[0046] [Ingredients] Polygonum multiflorum, aloe vera, cassia seed, medlar fruit, donkey-hide gelatin, ginseng, Atractylodes macrocephala, citrus aurantium.

[0047] [Functions and Indications] Nourishing yin and replenishing qi, purging turbidity and laxative. It is used for functional constipation. The TCM syndrome belongs to deficiency of both qi and yin and accumulation of toxins. Symptoms include constipation, abdominal distension, dry mouth and throat, fatigue, dysphoria and fever, red or pale tongue, white or white coating. White greasy, thready or slippery pulse.

Embodiment 2

[0048] Embodiment 2 capsule preparation

[0049] Polygonum multiflorum 25g Cassia seed 500g Aloe vera 30g

[0050] Lycium barbarum 150g donkey-hide gelatin 30g ginseng 100g;

[0051] Preparation:

[0052] Take the prescribed amount of donkey-hide gelatin and crush it into fine powder, pass through an 80-mesh sieve, and set aside; take the prescribed amount of ginseng, Polygonum multiflorum, Semen Cassiae, and aloe plus 60% ethanol for reflux extraction twice, add 10 times the amount for the first time, and add 8 times the amount for the second time. Double the amount, extract for 2 hours each time, filter separately, combine the filtrates, concentrate to a thick paste with a relative density of 1.30-1.35 (70°C), dry, grind, add donkey-hide gelatin powder and appropriate amount of dextrin, mix well, and dry method granules, put into capsules, and make 1000 granules.

Embodiment 3

[0053] Embodiment 3 capsule preparation

[0054] Polygonum multiflorum 25g Cassia seed 500g Aloe vera 30g

[0055] Lycium barbarum 150g Donkey-hide gelatin 30g Ginseng 100g

[0056] Citrus aurantium 50g Atractylodes macrocephala 100g;

[0057] Take the prescribed amount of donkey-hide gelatin and crush it into fine powder, pass through an 80-mesh sieve, and set aside; take the prescribed amount of ginseng, Polygonum multiflorum, Semen Cassiae, and aloe plus 60% ethanol for reflux extraction twice, add 10 times the amount for the first time, and add 8 times the amount for the second time. Double the amount, extract for 2 hours each time, filter separately, and combine the filtrates to obtain the filtrate Ⅰ; take the prescribed amount of Lycium barbarum, Atractylodes macrocephala, and Citrus aurantium, add water to decoct twice, add 8 times the amount of water for the first time, and soak for 1 hour , decocted for 1.5 hours, filtered, added 6 times the amount of water for the se...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition and application thereof. The invention relates to a new application of a traditional Chinese medicine composition developed on the basis of a patent ZL200410073958. X. The traditional Chinese medicine composition is mainly prepared from immature bitter orange, bighead atractylodes rhizome, ginseng, wolfberry fruit, donkey-hide gelatin, fleece-flower root, cassia seed and aloe. The traditional Chinese medicine composition can effectively reduce the levels of ALT, AST, GLB, TP, TC, TG and LDL-C in serum of a non-alcoholic fat rat induced by high fat diet and the content of MDA in the liver, and improve the levels of HDL-C and A / G in the serum and the activities of SOD, GSH and GSH-Px in the liver.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of the traditional Chinese medicine composition in the preparation of medicines for treating or improving fatty liver, and belongs to the technical field of traditional Chinese medicines. Background technique [0002] Fatty liver refers to the lesion of excessive fat accumulation in liver cells caused by various reasons. It is a common pathological change of the liver, rather than an independent disease. Fatty liver disease is seriously threatening the health of the Chinese people, becoming the second largest liver disease after viral hepatitis, the incidence rate is constantly increasing, and the age of onset is getting younger. Normal human liver tissue contains a small amount of fat, such as triglycerides, phospholipids, glycolipids, and cholesterol, and its weight is about 3% to 5% of the liver weight. If too much fat accumulat...

Claims

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Application Information

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IPC IPC(8): A61K36/886A61K36/896A61P1/16A61K35/36
CPCA61K36/704A61K36/482A61K36/896A61K36/886A61K36/815A61K35/36A61K36/258A61P1/16A61K2300/00
Inventor 程国良李冰冰叶士莉孙成磊
Owner LUNAN PHARMA GROUP CORPORATION
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