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Composition with anti-aging effect and application thereof

An anti-aging and composition technology, which is applied in the field of anti-aging compositions, can solve the problems of no application of Schizophyllum fermented products, deep color of Schizophyllum extract, and restrictions on oral products, and achieve obvious synergistic growth effect, enhance the activity of antioxidant enzymes, and inhibit secretion

Pending Publication Date: 2022-05-24
拜斯特药业(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the preciousness of wild Schizophyllum, the yield of artificially cultured fruiting bodies is limited, which directly affects its wide application.
At the same time, the schizophyllum extract is dark in color, and its application in oral products will be limited
Although Schizophyllum ferment (Schizophyllan) has been used in cosmetics, it has not been used in oral beauty products

Method used

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  • Composition with anti-aging effect and application thereof
  • Composition with anti-aging effect and application thereof
  • Composition with anti-aging effect and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0077] This preparation example provides a Schizophyllum fermented product, and the Schizophyllum fermented product is obtained by the following preparation method:

[0078] (A) Schizophyllum culture medium was prepared according to the following mass percentages: 5 g / L pueraria root powder, 0.3% yeast extract, 0.05% magnesium sulfate, 0.1% potassium dihydrogen phosphate, 3% glucose and the balance of water.

[0079] (B) 10% Schizophyllum (v / v, Schizophyllum seed solution / total volume of culture medium after inserting the seed solution) was inserted into the above-mentioned medium, and the fermentation was carried out at 28° C. and 150 r / min. After 120 hours of fermentation, the fermented product was centrifuged to remove bacterial cells and pueraria root powder to obtain a fermented product.

preparation example 2

[0081] This preparation example provides an olive extract, which is prepared by the following preparation method:

[0082] (a) olive raw material is extracted with water as solvent by PEF extraction method to obtain olive extract; wherein, the quality of olive raw material and the volume ratio of water are 1g:20mL, the field strength of extraction is 20kV / cm, and the number of pulses is 8 Second-rate;

[0083] (b) filtering and concentrating the olive extract obtained in step (a) to obtain extract; wherein, filtration adopts 200 mesh filter membrane, and the temperature of concentration is 80 ℃;

[0084] (c) after mixing the extract obtained in step (b) and maltodextrin, spray-drying to obtain the olive extract; wherein, the mass ratio of the extract and maltodextrin is 1:0.2, and the spray-dried The air temperature is 100°C, and the outlet air temperature is 70°C.

preparation example 3

[0086] This preparation example provides a prickly pear extract, and the prickly pear extract is prepared by the following preparation method:

[0087] (a) extracting the prickly pear raw material with water as a solvent by the PEF extraction method to obtain the prickly pear raw material; wherein, the mass of the prickly pear raw material and the volume ratio of water are 1g:10mL, the field strength of the extraction is 15kV / cm, the pulse The number of times is 6;

[0088] (b) filtering and concentrating the prickly pear extract obtained in step (a) to obtain an extract; wherein, a 300-mesh filter membrane is used for filtration, and the temperature of concentration is 75°C;

[0089] (c) after mixing the extract and maltodextrin obtained in step (b), spray-drying to obtain the prickly pear extract; wherein, the mass ratio of the extract and maltodextrin is 1:0.1, and the spray-dried The inlet air temperature is 90°C and the outlet air temperature is 70°C.

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Abstract

The invention provides a composition with an anti-aging effect and application thereof. The composition with the anti-aging effect is prepared from a schizophyllum commune fermentation product, a plant extract and collagen peptide. According to the mechanism of the composition acting on the aged skin, the composition can increase the content of hydroxyproline and hyaluronic acid in the skin and improve the antioxidant enzyme activity of a mouse body, and has an inhibiting effect on secretion of inflammatory cytokines.

Description

technical field [0001] The invention belongs to the technical field of health food, in particular to a composition with anti-aging effect and application thereof. Background technique [0002] Schizophyllum is a precious edible fungus, and the main active substance in its fruit body, mycelium and fermentation broth is schizophyllan. Studies have shown that it has pharmacological activities such as anti-tumor, antibacterial and anti-inflammatory, anti-radiation, and improving immunity. [0003] The main application in oral health food is the fruiting body extract of Schizophyllum. However, because wild Schizophyllum is precious, the yield of artificially cultured fruit bodies is limited, which directly affects its wide application. At the same time, the Schizophyllum extract is dark in color, and its application in oral products will be limited. Although the fermentation product of Schizophyllum (Schizophyllan) has applications in cosmetics, the application of the fermenta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/105A23L33/18A23L2/39A23L2/02A23L33/10A23L31/00C12P19/04C12R1/645
CPCA23L33/105A23L33/18A23L2/39A23L2/02A23L33/10A23L31/00C12P19/04A23V2002/00A23V2200/302A23V2200/318A23V2250/2131A23V2250/55A23V2300/14A23V2250/21A23V2250/2106
Inventor 孙怀庆裴运林李开莹郭朝万聂艳峰王宁
Owner 拜斯特药业(广州)有限公司
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