Application of rubus corchorifolius juice in preparing composition for conditioning skin

A technology of composition and application, which is applied in the direction of skin care preparations, cosmetic preparations, medical preparations containing active ingredients, etc., which can solve the problems of unfriendly environment and ecology, harmfulness to human health, rough skin, etc. Achieve the effects of reducing hemoglobin content, reducing red spots, and preventing skin aging

Pending Publication Date: 2022-02-22
TCI CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In addition, skin cells age gradually with age, and the skin texture becomes rough and wrinkled. Due to the slowing down of skin cell metabolism, the skin's recovery speed is gradually slowing down, coupled with long-term exposure to external environments such as air pollution. Stimulation, accumulation of a large amount of active oxygen species and melanin, etc. cannot be fully metabolized in time, resulting in skin condition that cannot be improved
[0004] Most of the known cosmetics, skin care products and health foods are made of chemical ingredients. Long-term use is not only harmful to human health, but also causes irritation to sensitive skin and aggravates skin redness. In addition, the manufacturing process is harmful to the environment and Ecologically unfriendly, causing environmental pollution, and even entering the ecosystem through the drainage system

Method used

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  • Application of rubus corchorifolius juice in preparing composition for conditioning skin
  • Application of rubus corchorifolius juice in preparing composition for conditioning skin
  • Application of rubus corchorifolius juice in preparing composition for conditioning skin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] [Example 1]: the preparation of the juice of dewberry (Rubus fruticosus)

[0060] First, the fruit of Rubus fruticosus (from Chile) is cut into a size of 12 mm, and then water, alcohols, hydroalcohols or a combination thereof are used as an extraction solvent to simultaneously homogenize and extract Rubus fruticosus. Extraction, wherein the extraction temperature is between 75°C and 95°C, preferably 80°C to 90°C, and the volume ratio of the extraction solvent to dewberry is between 5-20:1-5, preferably 5:1. The extraction temperature ranges from 50°C to 100°C, preferably from 80°C to 90°C. The extraction time in this embodiment is 0.5-3 hours, preferably 1 hour.

[0061] After the dewberry juice obtained through the above extraction steps is cooled to room temperature, it can be further centrifuged at 15°C-25°C for 5-10 minutes at a speed of 800-1300rpm to obtain a supernatant, which can be 400 mesh (mesh ) through a strainer to remove residual solids. Further concen...

Embodiment 2

[0062] [Example 2]: Detection of total flavonoids and total polyphenols content of dewberry juice

[0063] The analysis method for detecting the content of total flavonoids is mainly based on the method described by Zhishen Jia et al., (1999), Food Chemistry, 64: 555-559 and modified. Take 200 μL of an appropriately diluted sample and add 1000 μL of H 2 O. After mixing evenly, add 200 μL of 5% sodium citrate (Sodium nitrite), let it stand for 6 minutes, then add 200 μL of 10% aluminum nitrate (Aluminum nitrate), and let it stand for another 6 minutes. Finally, 2 mL of 4% sodium hydroxide (Sodium hydroxide) and 1.4 mL of H 2 O, mix well, analyze at 500nm, take rutin (Rutin) as the standard substance to draw the standard curve. In this example, the content of total flavonoids in the dewberry juice of Example 1 is between 1000 and 3000 ppm, preferably between 2000 and 3000 ppm, specifically 2248.9 ppm.

[0064] The analysis method for the detection of the total polyphenol conte...

Embodiment 3

[0065] [Example 3]: Cell experiment - dewberry juice inhibits generation of reactive oxygen species (ROS)

[0066] Herein, the fluorescent probe DCFH-DA was combined with a flow cytometer to measure the changes in the content of reactive oxygen species in human skin fibroblasts CCD-966sk treated with the dewberry extract composition.

[0067] Materials and Instruments

[0068] 1. Cell line: human dermal fibroblast CCD-966sk (Biological Resource Conservation and Research Center (BCRC), No. 60153), hereinafter referred to as CCD-966sk cell.

[0069] 2. Medium: basal medium containing 10 vol% FBS (fetal bovine serum, purchased from Gibco). Wherein, the basal medium is Eagle's minimum essential medium (Eagle's minimum essential medium (MEM), purchased from Gibco, product number 15188-319) with additional components added to make it contain 1mM sodium pyruvate (sodiumpyruvate, purchased from Gibco), It was prepared with 1.5 g / L sodium bicarbonate (sodium bicarbonate, purchased fr...

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Abstract

The invention provides application of rubus corchorifolius juice in preparing a composition for conditioning skin. The composition is used for reducing oxidative damage caused by reactive oxygen species in cells, reducing the hemachrome content of the skin, inhibiting melanogenesis, reducing red spots of the skin and improving the moisturizing capacity of the skin.

Description

technical field [0001] This case is about the use of a dewberry (Rubus fruticosus) juice, in particular about the use of the dewberry juice for preparing a composition for conditioning the skin. Background technique [0002] As the environment changes, the UV index and air pollution are becoming more and more serious. The ultraviolet radiation in the sun is the main cause of skin damage, aging, and tanning. Skin exposed to the sun for a long time may even produce melanin and spots, which are difficult to fade away. In addition, ultraviolet radiation in the sun will promote the generation of reactive oxygen species (reactive oxygen species, ROS, also known as free radicals) in skin cells, resulting in skin aging, loss of luster, dryness, etc., and even redness. [0003] In addition, skin cells age gradually with age, and the skin texture becomes rough and wrinkled. Due to the slowing down of skin cell metabolism, the skin's recovery speed is gradually slowing down, coupled wi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/02A61Q19/08A61Q17/04A23L33/105
CPCA61K8/9789A61Q19/02A61Q19/08A61Q17/04A23L33/105A23V2002/00A61K2800/782A61K2800/92A23V2200/318A61Q19/00A61K2800/805A61Q19/007
Inventor 林咏翔李唯君
Owner TCI CO LTD
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