Preparation method of ortho-aminophenol

A technology of o-aminophenol and nitrobenzene, which is applied in the field of preparation of o-aminophenol, can solve the problems of high environmental protection treatment cost and high synthesis cost, and achieve the effects of high production efficiency, stable product quality and simple operation process.

Pending Publication Date: 2022-02-11
江苏普洛德化学科技有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The defect is that the hydrolysis and reduction steps must be high temperature and high pressure, resulting in a large amount of waste brine. Although the product purity can be achieved, the cost of environmental pr

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of ortho-aminophenol
  • Preparation method of ortho-aminophenol
  • Preparation method of ortho-aminophenol

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] In order to deepen the understanding of the present invention, the present invention will be further described below in conjunction with the embodiments and accompanying drawings. The embodiments are only used to explain the present invention and do not constitute a limitation to the protection scope of the present invention.

[0023] One, the preparation of o-aminophenol:

[0024] The raw material sample specifications for preparing o-aminophenol are shown in the table below:

[0025]

[0026] Prepare as follows:

[0027] S1. Using water, nitrobenzene, and sulfuric acid as raw materials, add catalyst Pt-c and pass in hydrogen gas. The operating pressure of hydrogen gas is 0.3-0.5Mpa. Nitrobenzene, hydrogen gas, and water undergo hydrogenation and reduction reactions to generate phenylhydroxylamine. , through sulfuric acid transposition to generate o-aminophenol sulfate, and through neutralization with ammonia water to obtain o-aminophenol and ammonium sulfate;

[...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a preparation method of ortho-aminophenol, which specifically comprises the following steps: (1) taking water, nitrobenzene and sulfuric acid as raw materials, adding a catalyst, and preparing an initial reaction solution under the condition of introducing hydrogen; (2) carrying out solid-liquid separation on the initial reaction solution, taking a solid substance as the catalyst, and reusing the solid substance in S1, wherein a liquid substance is a mixture solution; and (3) adjusting the pH of the mixture solution by a basic substance to neutrality. According to the preparation method of ortho-aminophenol, nitrobenzene is used for replacing ortho-nitrochlorobenzene, high-pressure hydrolysis and high-temperature and high-pressure reduction are not needed, reaction conditions are mild, the operation process is simple, safety is high, production efficiency is high, productivity is high, the product cost is reduced, and the overall benefit is increased.

Description

technical field [0001] The present invention relates to the field of organic synthesis, in particular to a preparation method of o-aminophenol. Background technique [0002] Ortho-aminophenol (OPA) is an important chemical intermediate widely used in dyestuffs, medicine, printing and other fields. |The traditional process of preparing o-aminophenol is to nitrate phenol at low temperature to obtain a mixture of p-nitrophenol and o-nitrophenol, which is separated and then hydrogenated and reduced (high temperature and high pressure) to obtain o-aminophenol. Its disadvantages are that the safety of the nitration process cannot be guaranteed. In addition to a certain amount of p-nitrophenol produced during the nitration process, there is also a part of tar. The yield is low, the product purity is unstable, it is difficult to deal with environmental protection, and the cost is high. [0003] At present, the domestic market uses o-nitrochlorobenzene and liquid caustic soda to hyd...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C213/00C07C215/76
CPCC07C239/10C07C213/00C07C215/76
Inventor 周龙根周鑫周宸萱徐丹于冬英
Owner 江苏普洛德化学科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap