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Long-acting easy-to-clean sunscreen cream and preparation method thereof

A sunscreen and easy-to-clean technology, applied in the direction of medical preparations containing active ingredients, skin care preparations, pharmaceutical formulas, etc., can solve the problems of short residence time, poor sun protection durability, easy to fall off, etc., to improve adhesion, The effect of prolonging the sun protection time

Pending Publication Date: 2021-11-16
何花
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Compared with chemical sunscreens, TiO 2 It is favored because of its wide sunscreen band, good photostability, and low risk of allergic reactions. However, this physical sunscreen also has the problems of easy peeling, short residence time on the skin, and poor sunscreen durability.

Method used

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  • Long-acting easy-to-clean sunscreen cream and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] A long-acting and easy-to-clean sunscreen, including the following components in mass percentages: titanium dioxide@formylated chondroitin sulfate / gelatin 15%, octocrylene 3%, ethylhexyl triazone 1%, butylmethoxy Dibenzoylmethane 3%, Sorbitan Sesquioleate 3%, Methyl Methacrylate Crosspolymer 0.5%, Bakelyl Alcohol 1.5%, Caprylic / Capric Triglyceride 1.5%, Panthenol 1.5 %, betaine 2.5%, sodium hyaluronate 6%, and the balance is water.

[0033] The preparation method of the titanium dioxide@formylated chondroitin sulfate / gelatin is as follows:

[0034] (A) placing titanium dioxide in a ball mill, and ball milling for 3 hours at a temperature of 100° C. and a rotational speed of the ball mill of 500 r / min to obtain pretreated titanium dioxide;

[0035] (B) In the dark, at 25°C, add 5.5wt% sodium periodate solution dropwise while stirring in 9wt% chondroitin sulfate solution, between the chondroitin sulfate solution and sodium periodate solution The volume ratio is 10:1. Af...

Embodiment 2

[0043] A long-acting and easy-to-clean sunscreen, comprising the following components in mass percentages: titanium dioxide@formylated chondroitin sulfate / gelatin 18%, phenylbenzimidazole sulfonic acid 0.6%, ethylhexyl salicylate 1 %, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine 1.9%, Polyhydroxystearic Acid 4%, Tapioca Starch 0.6%, Caprylic / Capric Triglyceride 2.5%, Squalane 4%, 1,2 - Hexylene glycol 1%, betaine 3.5%, sodium hyaluronate 2.5%, balance water.

[0044] The preparation method of the titanium dioxide@formylated chondroitin sulfate / gelatin is as follows:

[0045] (A) Titanium dioxide is placed in a ball mill, and ball milled for 2 hours at a temperature of 150° C. and a rotational speed of the ball mill of 400 r / min to obtain pretreated titanium dioxide;

[0046] (B) In the dark, at 30°C, add 4.5wt% sodium periodate solution dropwise while stirring in 11wt% chondroitin sulfate solution, between the chondroitin sulfate solution and sodium periodate solution The ...

Embodiment 3

[0054] A long-lasting and easy-to-clean sunscreen, including the following components in mass percentages: titanium dioxide@formylated chondroitin sulfate / gelatin 20%, cetearyl glucoside 5%, carbomer 0.8%, shark liver Alcohol 4%, Caprylic / Capric Triglyceride 2.6%, Squalane 3.4%, Panthenol 1.5%, Betaine 3.5%, balance water.

[0055] The preparation method of the titanium dioxide@formylated chondroitin sulfate / gelatin is as follows:

[0056] (A) Put titanium dioxide in a ball mill, and ball mill for 1 hour at a temperature of 200° C. and a rotation speed of the ball mill of 300 r / min to obtain pretreated titanium dioxide;

[0057] (B) In the dark, at 35°C, add 3.5wt% sodium periodate solution dropwise while stirring in 13wt% chondroitin sulfate solution, between the chondroitin sulfate solution and sodium periodate solution The volume ratio of the solution is 8:1. After the dropwise addition, continue to react at 35°C for 3.5 hours, add ethylene glycol to terminate the reaction...

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Abstract

The invention relates to the field of cosmetics, and discloses a long-acting and easy-to-clean sunscreen cream and a preparation method thereof. The sunscreen cream is prepared from the following components in percentage by mass: 15 to 20 percent of titanium dioxide@formylated chondroitin sulfate / gelatin, 0 to 7 percent of a chemical sunscreen agent, 3 to 5 percent of an emulsifier, 0.5 to 0.8 percent of a thickening agent, 3 to 10 percent of a softening and moistening agent, 5 to 10 percent of a humectant and the balance of water. According to the invention, formylated chondroitin sulfate and gelatin are grafted on the surface of titanium dioxide, on one hand, the adhesion of titanium dioxide on the skin surface can be improved, so that the sunscreen time is prolonged; and on the other hand, the characteristic that the it is easy to clean titanium dioxide through cold water is achieved, and the titanium dioxide an be washed off only by contacting with a large amount of cold water, so that no residue is left on the skin surface.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a long-acting and easy-to-clean sunscreen and a preparation method thereof. Background technique [0002] In addition to visible light in sunlight, about 1% of ultraviolet rays with a wavelength of 290-400nm can irradiate the earth's surface, which is the main ray in sunlight that may damage the skin. Among them, electromagnetic waves with a wavelength of 290-320nm belong to medium-wave ultraviolet (UVB), which has an erythema effect on human skin. It can reach the dermis, sunburn the skin, and cause peeling, erythema, and sunburn; Belonging to long-wave ultraviolet rays (UVA), it is called "age ultraviolet light", which is the main cause of premature aging of human skin. It can penetrate the dermis, cause damage to lipids and collagen, cause skin aging and even skin cancer. The depletion of ozone in the atmosphere also makes people pay more and more attention to the damage of ultraviol...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/65A61K8/29A61K8/891A61K8/34A61Q17/04
CPCA61K8/735A61K8/65A61K8/29A61K8/891A61K8/342A61Q17/04A61K2800/805A61K2800/782
Inventor 何花
Owner 何花
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