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High-absorptivity wound dressing

A wound dressing, high absorbency technology, applied in the field of medical devices, can solve the problems of reduced absorption capacity, easy breakage, and aggravation of dressings, and achieves the effect of ensuring the absorption of exudate, ensuring fit and contact, and high adaptability

Pending Publication Date: 2021-09-21
元睦生物科技(上海)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Lymphatic obstruction or failure secondary to other pathophysiological causes, such as venous hypertension that prevents fluid reabsorption from tissues back into lymphatic vessels
[0006] 4. Patients who sleep in a chair at night or do not elevate their legs effectively will experience heavier exudates from their feet and calves due to gravity and often manifest as skin changes such as macerated toes or heels The tissue around the wound becomes "wet," more fragile and more easily damaged
[0009] 7. Certain wound treatments may increase (or significantly increase) fluid loss from the wound
[0011] 1. Excess wound fluid and excessive levels of proteases have been shown to interfere with wound healing, and these proteases (matrix metalloproteinases MMP in chronic wound exudate) damage healthy tissue, thereby complicating the healing process and causing environmental macerated skin, broken and peeled skin, enlarged wound, increased discharge, and increased pain
[0012] 2. When the dressing is saturated and moisture penetration occurs, there is a risk of infection
[0013] 4. Large amounts of exudate not contained in the dressing can leak and stain the patient's clothing, footwear, or bedding
[0018] Described in CN101721733B is a kind of chitosan fiber spinning, be cut into short fiber, on the chitosan short fiber spray-coated silver-loaded nano-titanium dioxide particle, the medical chitosan antiseptic dressing that makes, this dressing is owing to only using shell Polysaccharide fiber, the fiber strength is not enough, it is easy to break during use, resulting in fragments
[0021] 1. There is a type of foam exudate dressing on the market. The dressing itself is not designed to store a large amount of exudate, but absorbs a large amount of exudate from one side of the dressing, and then evaporates a large amount of water in the exudate through the other side. A large amount of evaporation leads to The wound dries out and sticks to the foam, causing wound damage and great pain to the patient when the dressing is removed;
[0022] 2. In addition, this type of dressing has no ability to retain exudate, and cannot retain exudate against gravity. In addition, when subjected to external pressure (such as a patient with a large amount of venous venous ulcer exudation in the lower extremity, accompanied by edema of the lower extremity with a pressure bandage), the dressing's The absorption capacity will be reduced. When the external pressure reaches a certain level, such as the dressing on the bedsore of an obese patient, the exudate under pressure will be squeezed out of the dressing;
[0023] 3. Due to the open structure of the foam, it does not prevent the lateral expansion of seepage;
[0024] 4. When a large amount of exudation occurs, the ability to absorb liquid is limited, resulting in maceration of the surrounding skin;
[0025] 5. It is easy to be infected for a long time, and there are reports of foul-smelling discharge

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0145] Production process of alginate, pectin and carboxymethyl fiber composite antibacterial non-woven mat

[0146] 1) Preparation of spinning dope

[0147] In 200 kilograms of demineralized water, add 10 kilograms of sodium alginate (selected from Qingdao Mingyue Biomedical Materials Co., Ltd.) and 1 kilogram of carboxymethyl cellulose (CMC selected from Walocel of Dow Chemical in the United States) respectively. TM High-purity carboxymethyl cellulose) and 1 kg of high-methoxyl pectin (selected from Wuhan Dahua Weiye Medical Chemical Co., Ltd.), stirring and dissolving at room temperature for 24-48 hours, so that various substances are fully dissolved and defoamed;

[0148] 2) spinning forming

[0149] The above-mentioned spinning stock solution is extruded through the spinneret holes under pressure, solidified in the coagulation bath, and drawn 2-6 times in the drawing bath at 60-90°C;

[0150] 3) Drying and finishing

[0151] The fibers are washed with water, then dried...

Embodiment 2

[0156] Production process of alginate silver dressing

[0157] Produce composite gel fiber by the method for example 1 by the co-spinning of carboxymethyl cellulose fiber and calcium alginate fiber, calcium alginate fiber comes from domestic A company, and CMC fiber comes from Walocel of U.S. Dow Chemical TM High-purity carboxymethyl cellulose, the gel fiber contains 16% CMC and 84% calcium alginate, the thickness is about 2-6 denier, and the length is 4-5cm;

[0158] The non-gel fiber adopts the nylon 6.6 fiber (trade name ionic) that has been coated with 99.9% silver of Nobel Biomaterial company TM ), the thickness is about 100-150 denier, and the length is 4-5cm; the gel fibers and non-gel fibers are separated loosely and mixed according to 60% gel fibers and 40% non-gel fibers, and sent into the web The machine forms a carded fiber web, feeds the carded fiber web into a cross-lapper and folds it into a continuous 5-10cm thick cross-web, and then sends it to a needle punch...

Embodiment 3

[0159] Embodiment 3 Absorbency, wet and dry strength test method and test

[0160] 1. Test method for absorbency.

[0161] (1) Preparation of solution A: Take a 1L volumetric flask, dissolve 8.298 g of sodium chloride and 0.368 g of calcium chloride dihydrate with a small amount of deionized water and dilute to make 1 L. The solution contains 142mmol of sodium ions and 2.5mmol of calcium ions. The ion content of the solution is equivalent to that of human serum or wound exudate, and is used as a body fluid simulation fluid.

[0162] (2) Place the sample in a constant temperature and humidity oven for 24 hours, take it out and accurately cut it into 5x 5cm, and measure its actual size with a standard steel ruler;

[0163] (3) Place the empty Petri dish on the balance and tare it;

[0164] (4) Put a 5 x 5 cm dressing sample into a Petri dish and record the weight (W1) to 3 decimal places, remove the Petri dish and sample from the balance;

[0165] (5) Add solution A at 37°C t...

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Abstract

The invention provides a high-absorptivity wound dressing which comprises a backing layer, a reinforcing layer, an absorbing layer and a super absorbing layer, and the absorbing layer can be a melt-blown non-woven fabric pad, a three-dimensional casting made of composite fibers, polyurethane foam or a combination of two or more of the melt-blown non-woven fabric pad, the three-dimensional casting made of the composite fibers and the polyurethane foam; the absorbing layer at least contains one or more of composite gel fibers, non-gel fibers, biodegradable components and at least one or more of antibacterial components; and the super absorbing layer at least contains one kind of high-absorptivity polymer particles which are wrapped in a double-layer non-woven fiber net or foam. The high-absorptivity wound dressing not only can vertically wick and store a large amount of seepage, but also is high in softness and good in fitting degree, and leakage and pain of a patient are reduced to the maximum extent.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a wound dressing, which specifically includes a high-absorption material that can vertically wick and store a large amount of exudate, has high flexibility, good fit, and minimizes leakage and patient pain. Sexual wound dressing and method for its preparation. Background technique [0002] Wound exudate management is a big problem and a huge challenge because exudate can be quite volumetric and very variable. Possible causes of hyperexudate include the following: [0003] 1. Chronic inflammatory responses can lead to highly exudative wounds (Hart, 2002). Inflammatory ulcers such as those associated with rheumatoid arthritis or vasculitis, large wounds naturally produce more exudate, and burns produce more exudate (UK Wounds, 2013). [0004] 2. Lymphatic obstruction or failure secondary to other pathophysiological causes, such as venous hypertension that prevents reabsorp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F13/02A61L15/28A61L15/46A61L15/42A61L15/60A61L15/18
CPCA61F13/0206A61F13/0209A61F13/0223A61F13/0213A61F13/00063A61L15/28A61L15/46A61L15/425A61L15/60A61L15/42A61L15/18A61L2300/404A61L2300/104C08L1/286C08L5/04
Inventor 陈健恒邵化冰
Owner 元睦生物科技(上海)有限公司
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