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External traditional Chinese medicine preparation for treating HPV infection and preparation method thereof

A technology of traditional Chinese medicine preparations and raw materials, which is applied in the direction of medical preparations with non-active ingredients, medical preparations containing active ingredients, and pharmaceutical formulas. It can solve the problems of dependence, high cost, and low transdermal absorption rate, and achieve low cost. , easy to use, good dispersion effect

Pending Publication Date: 2021-05-07
河南骨痹中医研究院(有限合伙)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among several methods, HPV vaccination is an effective method, but there are still some obstacles in the promotion of HPV vaccines. The obstacle that ordinary people can directly perceive is the high cost. Therefore, most areas of China are currently facing HPV In the treatment of infection, physical therapy and drug therapy are still mainly used to remove local hyperplastic warts, and the selection is still effective, simple, safe, and does not cause scars; the physical therapy method is mainly ozone water cleaning, The use of machines to produce ozone, ozone has strong oxidative properties, destroys the genetic material of viruses, and achieves the effect of killing viruses. Fukang suppository treatment, in which interferon is a broad-spectrum antiviral agent, which does not directly kill the virus, but mainly makes the cells produce antiviral protein through the action of cell surface receptors, thereby inhibiting the replication of the virus, but on the one hand, It can not solve the problems induced by HPV infection such as gynecological inflammation and low metabolic immunity. On the other hand, it is a recombinant human interferon obtained by using biotechnology, and the cost is also high. virus, and Baofukang suppository is a kind of Chinese patent medicine, which is a suppository for external use. , is an ideal drug, but its transdermal absorption rate is low, and the therapeutic effect needs to be further strengthened

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] An external Chinese medicine preparation for treating HPV infection: it is made of the following raw materials in parts by weight: 1 part of comfrey, 10 parts of rhodiola, 1 part of Brucea javanica, 10 parts of rhubarb, 1 part of curcuma, 10 parts of Bupleurum, 1 part pungent, 10 parts honeysuckle, 1 part angelica, 10 parts motherwort, 1 part chuanxiong, 10 parts Kochia scoparia, 1 part coptis, 10 parts salvia, 1 part rhubarb, 10 parts forsythia, 1 part flavescens, 10 leaves 1 part of Zanthoxylum bungeanum, 1 part of Houttuynia cordata, 1 part of Desmodium, 5 parts of Banlangen, 1 part of Artemisia annua, 5 parts of Haijinsha, 1 part of Scutellaria baicalensis, 5 parts of Lonicerae vine, 1 part of Cortex Phellodendri, and 150 parts of lipid body.

[0050] Further, the liposome is polyoxyethylene polyoxypropylene copolymer. More specifically Poloxamer 188 (Poloxamer188)

[0051] A preparation method of an external Chinese medicinal preparation for treating HPV infectio...

Embodiment 2

[0065] An external Chinese medicine preparation for treating HPV infection: it is made of the following raw materials in parts by weight: 10 parts of comfrey, 1 part of Rhodiola rosea, 10 parts of Brucea javanica, 1 part of rhubarb, 10 parts of curcuma, 1 part of Bupleurum, 10 parts of pungent, 1 part of honeysuckle, 10 parts of angelica, 1 part of motherwort, 10 parts of Chuanxiong, 1 part of Kochia, 10 parts of coptis, 1 part of salvia, 10 parts of rhubarb, 1 part of forsythia, 10 parts of flavescens, and 1 part of mugwort 10 parts of Zanthoxylum bungeanum, 1 part of Houttuynia cordata, 5 parts of Desmodium, 1 part of Banlangen, 5 parts of Artemisia annua, 1 part of Haijinsha, 5 parts of Scutellaria baicalensis, 1 part of Lonicerae vine, 5 parts of Cortex Phellodendri, and 50 parts of lipid body.

[0066] Further, the liposome is polyoxyethylene polyoxypropylene copolymer. More specifically Poloxamer 188 (Poloxamer188)

[0067] A preparation method of an external Chinese m...

Embodiment 3

[0081] An external Chinese medicine preparation for treating HPV infection: made of the following raw materials in parts by weight: 6 parts of comfrey, 9 parts of Rhodiola rosea, 3 parts of Brucea javanica, 4 parts of rhubarb, 7 parts of curcuma, 5 parts of Bupleurum, 6 parts of pungent, 6 parts of honeysuckle, 5 parts of angelica, 4 parts of Motherwort, 9 parts of Chuanxiong, 3 parts of Kochia, 7 parts of Coptidis, 6 parts of Salvia, 8 parts of rhubarb, 2 parts of forsythia, 2 parts of Sophora flavescens, 6 parts of Artemisia argyi 4 parts of Chinese prickly ash, 2 parts of Houttuynia cordata, 3 parts of money grass, 2 parts of Radix Radix, 2 parts of Artemisia annua, 3 parts of Haijinsha, 2 parts of Scutellaria baicalensis, 2 parts of honeysuckle, 4 parts of Cortex Phellodendri, and 100 parts of lipid body.

[0082] Further, the liposome is polyoxyethylene polyoxypropylene copolymer. More specifically Poloxamer 188 (Poloxamer188)

[0083] A preparation method of an externa...

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Abstract

The invention discloses an external traditional Chinese medicine preparation for treating HPV infection and a preparation method thereof. The external traditional Chinese medicine preparation for treating HPV infection is prepared from the following raw materials: lithospermum, rhodiola rosea, brucea javanica, rumex madaio, curcuma zedoary, radix bupleuri, asarum, honeysuckle, angelica sinensis, leonurus, ligusticum wallichii, fructus kochiae, coptis chinensis, salviae miltiorrhizae, rheum officinale, fructus forsythiae, radix sophorae flavescentis, folium artemisiae argyi, pepper, houttuynia cordata, lysimachia christinae hance, isatis root, artemisia apiacea, lygodium japonicum, scutellaria baicalensis, honeysuckle stem and golden cypress. The preparation method of the external traditional Chinese medicine preparation for treating HPV infection comprises the following steps of: crushing the raw materials at low temperature; extracting raw material micro powder; and wrapping extract by using lipidosome.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an external Chinese medicine preparation for treating HPV infection and a preparation method thereof. Background technique [0002] It has been confirmed that HPV infection is a necessary factor for cervical cancer and precancerous lesions. The current treatment methods for cervical HPV infection in my country mainly include physical therapy, drugs, and vaccines. Among several methods, HPV vaccination is an effective method, but there are still some obstacles in the promotion of HPV vaccines. The obstacle that ordinary people can directly perceive is the high cost. Therefore, most areas of China are currently facing HPV In the treatment of infection, physical therapy and drug therapy are still mainly used to remove local hyperplastic warts, and the selection is still effective, simple, safe, and does not cause scars; the physical therapy method ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/127A61K9/06A61K47/32A61P31/20
CPCA61K9/0034A61K9/06A61K9/127A61K36/12A61K36/185A61K36/195A61K36/232A61K36/233A61K36/236A61K36/268A61K36/282A61K36/30A61K36/315A61K36/355A61K36/41A61K36/489A61K36/53A61K36/533A61K36/537A61K36/539A61K36/634A61K36/70A61K36/708A61K36/718A61K36/756A61K36/758A61K36/78A61K36/9066A61K47/32A61K2236/37A61P31/20A61K2300/00
Inventor 雷灿宾
Owner 河南骨痹中医研究院(有限合伙)
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