Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence

A nano-zinc oxide and stem cell technology, applied in the field of stem cell essence and its preparation, can solve the problems of human health hazards, poor chemical stability, toxicity and carcinogenicity, etc., achieve excellent antibacterial performance, extend shelf life, and repair damaged skin tissue Effect

Pending Publication Date: 2021-03-26
ZHENGZHOU UNIV +3
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, daily-use cosmetics are rich in nutrients and are particularly prone to breed microorganisms. In addition to changing the color, aroma and taste of cosmetics, pathogenic microorganisms and their metabolites can also cause harm to human health
At present, there are many broad-spectrum antibacterial substances used in cosmetics, but there are some fatal problems, such as poor chemical stability, poor heat resistance, and certain toxicity and carcinogenicity.
Moreover, most of them are organic antibacterial agents, and the problem of drug resistance caused by the application of organic antibacterial agents has become a huge challenge for human beings in the new century.
In particular, the emergence of superbugs in recent years poses a serious challenge to the use of traditional antibacterial agents

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence
  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence
  • Stem cell essence containing hydrophilic nano-zinc oxide and preparation method of stem cell essence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preparation of embodiment 1 hydrophilic zinc oxide quantum dots

[0030] Synthesis of hydrophilic zinc oxide quantum dots: Take 35mM potassium hydroxide into a 50mL beaker, add 20mL of absolute ethanol and stir for 15min until the potassium hydroxide is completely dissolved, and place in a refrigerator at 4°C to refrigerate. Add 25mM zinc acetate and dihydrate into a single-necked flask filled with 150mL of absolute ethanol, stir and reflux at 80°C until the zinc acetate is completely dissolved (about 2h), then place the mixture in an ice bath. Add the ethanol solution of potassium hydroxide dropwise to the single-necked flask containing the ethanol solution of zinc acetate, and keep stirring to fully react for 30 minutes. At this time, the phenomenon that the reaction solution changes from clear to cloudy and then gradually clear can be observed. The reaction mixture was taken out of the ice bath and when the temperature returned to room temperature, 1.5 mL of dei...

Embodiment 2

[0046] Example 2 Preparation of Stem Cell Essence Containing Hydrophilic Nano Zinc Oxide

[0047] Use the hydrophilic zinc oxide quantum dots prepared in Example 1 to prepare the present invention containing hydrophilic nano-zinc oxide stem cell essence, the production process is as follows figure 1 As shown, the following steps are taken:

[0048] (1) Weigh each component according to the formula: stem cell conditioned medium 60% (volume / volume), glycerin 3% (volume / volume), hydrophilic nano zinc oxide quantum dots 0.6% (mass / volume), aloe extract Extract 0.25% (mass / volume), collagen extract 2% (mass / volume), pearl hydrolyzate 0.25% (mass / volume), carbomer 0.5% (mass / volume), triethanolamine 0.5% (mass / volume) / volume), allantoin 0.5% (mass / volume), sodium hyaluronate 4% (mass / volume), egg white synthetic powder 2.5% (mass / volume), panthenol 0.5% (mass / volume), dextrose Sugar 0.5% (mass / volume), glycyrrhetinic acid 0.5% (mass / volume), and the balance is purified w...

Embodiment 3

[0052] Example 3 Preparation of Stem Cell Essence Containing Hydrophilic Nano Zinc Oxide

[0053] Use the hydrophilic zinc oxide quantum dots prepared in Example 1 to prepare the present invention containing hydrophilic nano-zinc oxide stem cell essence, the production process is as follows figure 1 As shown, the following steps are taken:

[0054] (1) Weigh each component according to the formula: stem cell conditioned medium 50% (volume / volume), glycerin 2% (volume / volume), hydrophilic nano zinc oxide quantum dots 0.4% (mass / volume), aloe extract Extract 0.5% (mass / volume), collagen extract 5% (mass / volume), pearl hydrolyzate 0.5% (mass / volume), carbomer 0.8% (mass / volume), triethanolamine 0.8% (mass / volume) / volume), allantoin 0.7% (mass / volume), sodium hyaluronate 6% (mass / volume), egg white synthetic powder 3% (mass / volume), panthenol 0.7% (mass / volume), dextran Sugar 0.8% (mass / volume), glycyrrhetinic acid 0.7% (mass / volume), and the remainder is purified wate...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Transmittanceaaaaaaaaaa
Login to view more

Abstract

The invention provides stem cell essence containing hydrophilic nano-zinc oxide. Based on the characteristic that the stem cells repair the skin tissues, complex factors secreted by the stem cells canbe stored in the skin tissues for a long time, play a role in regulating and repairing the skin cells through skin microcirculation regulation of the human body, eliminate free radicals, prevent oxidation, diminish inflammation and promote tissue regeneration. According to the stem cell essence containing the hydrophilic nano-zinc oxide, added hydrophilic zinc oxide quantum dots show infrared spectrum absorption peaks at 3425 cm<-1>, 2936 cm<-1>, 1574 cm<-1>, 1405 cm<-1>, 1018 cm<-1> and 525 cm<-1> and have obvious destructiveness on staphylococcus aureus and escherichia coli, so that the cell walls of the treated bacteria are shrunk and seriously damaged; and meanwhile, the hydrophilic zinc oxide quantum dots also have an obvious inhibiting effect on enterococcus faecium, bacillus cereus, bacillus megaterium and micrococcus luteus, so that the antibacterial property is excellent, and the shelf life of a product is effectively prolonged. The preparation method is simple and suitable for industrial production.

Description

technical field [0001] The invention relates to a stem cell essence containing hydrophilic nanometer zinc oxide and a preparation method thereof, belonging to the technical field of cosmetics. Background technique [0002] With the improvement of living standards, anti-aging has become a topic of concern to more and more people. Anti-aging products continue to experience strong growth, with more than half of the market focused on anti-aging products that delay or reduce the effects of aging, according to Kline, a world-renowned consultancy and research firm. Stem cells are one of the most attractive fields in modern biology and medicine, and are an important direction of life science research. Mesenchymal stem cells have great advantages as the seed cells of stem cell anti-aging products. They have a wide range of sources, are easy to isolate and culture, have huge potential for in vitro expansion, and have unique immunological characteristics. They have the potential to be...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K8/99A61K8/27A61K8/34A61K8/42A61K8/49A61K8/63A61K8/65A61K8/73A61K8/81A61K8/9794A61K8/98A61Q17/00A61Q19/00A61Q19/08C01G9/02B82Y40/00B82Y30/00
CPCA61K8/99A61K8/27A61K8/9794A61K8/65A61K8/987A61K8/8147A61K8/4946A61K8/735A61K8/982A61K8/345A61K8/42A61K8/73A61K8/63A61Q19/08A61Q19/00A61Q17/005C01G9/02B82Y30/00B82Y40/00A61K2800/413C01P2004/64C01P2004/04C01P2004/10
Inventor 刘凯凯赵文博高萧芳赵辉单崇新
Owner ZHENGZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap