Chinese and western medicine compound film coating agent for treating bovine acariasis and preparation method thereof

Abstract

The invention belongs to the technical field of animal medicaments, and particularly discloses a Chinese and western medicine compound film coating agent for treating bovine acariasis and a preparation method thereof. Every 1000 mL of the film coating agent is prepared from the following materials: 3 to 8 g of abamectin, 20 to 40 g of eugenol, 30 to 50 g of L-menthol, 40 to 60 mL of N-methyl pyrrolidone, 18 to 22 g of polyvinyl alcohol 124, 42 to 48 mg of xanthan gum, 70 to 80 mL of glycerol, 500 mL of water, 20 ml of AEO-9, 100 ml of propylene glycol, 0.5 g of grape purple and the balance ofethanol. The film coating agent prepared by the method has the advantages of good film forming property, good adhesiveness, difficulty in falling, lasting curative effect, small stress and safety in use. According to the severity of an affected part, the film coating agent can be poured along the middorsal line backwards from the shoulders for a patient in less severe case, and the film coating agent can be directly smeared to the affected part for a patient in severe case. A formula and the preparation method are unique, the treatment effect is remarkable, a protective film can be formed, medicine in an inner layer of the film is permeated and absorbed, an outer layer of the film plays a protective role and cannot fall off automatically, and the film coating agent has the advantages incomparable to those of a pouring agent.

Description

technical field [0001] The invention relates to the technical field of animal medicaments, in particular to a Chinese and Western medicine compound coating agent for treating bovine acariasis and a preparation method thereof. Background technique [0002] Cattle mite disease is a common ectoparasitic disease caused by mites. It is sporadic and endemic, and is characterized by severe itching and eczema-like dermatitis. Caused by mange bovine, itchy bovine, bovine foot mite and / or bovine demodex, with the previous two predominately. In recent years, with the expansion of the scale of the breeding industry, more and more cattle are being raised, and the sanitation and environmental conditions are still in a very poor state. Therefore, the probability of occurrence of bovine acariosis is also increasing. It is harmful to the cattle industry. [0003] The affected cattle are thin, and nodules and blisters appear on the skin of the neck, wattles and shoulders. Due to severe itch...

AI Technical Summary

Problems solved by technology

[0004] The chemical synthesis and antibiotic drugs currently used to treat animal mites effectively prevent and control animal mites, but their clinical application is greatly limited due to drug residues and drug resistance.

Some traditional Chinese medicines for the treatment of this disease have low bioavailability and poor clinical effect due to their unreasonable formula or simply crushed, large particle size and slow drug release.

Therefore research and develop a kind of low toxicity for the treatment of bovine mite, do not cause residue, have no drug resistance and have special effect medicine is one of the new problems waiting to be solved urgently, there is not yet the research report of this aspect in the prior art

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