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Heparin-based blood sampler without platelet activation

A sampler and blood sample technology, applied in the field of diagnostic blood sample analysis, can solve problems such as interference with electrolyte measurement, interference measurement, and unusability

Pending Publication Date: 2020-06-30
RADIOMETER AS
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Problems solved by technology

However, EDTA or citrate cannot be used for BG and BMP parameter analysis because these anticoagulants can severely interfere with electrolyte measurements
For example, EDTA and citrate with Ca 2+ Form a complex that interferes with Ca 2+ measurement, and these anticoagulants may even destroy the calcium sensor of the automated analyzer

Method used

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  • Heparin-based blood sampler without platelet activation
  • Heparin-based blood sampler without platelet activation
  • Heparin-based blood sampler without platelet activation

Examples

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Embodiment Construction

[0029] The present invention relates to an in vitro method for preparing a blood sample, wherein the blood is combined with: a) at least one anticoagulant for determining BG and BMP parameters; and b) at least one antiplatelet agent. The inventors have surprisingly found that blood samples prepared according to the inventive method are suitable for BG and BMP parameter analysis as well as platelet count. Thus, an advantage of the inventive method of the present invention is that it allows "3 in 1" analysis with one blood sample. In a preferred embodiment, said blood sample is also suitable for WBC counting. Therefore, blood samples obtained by the inventive method are preferably suitable for analysis of BG and BMP parameters and complete blood count (CBC).

[0030] In another aspect, the present invention relates to a method for preparing a sample for blood analysis, said method comprising the steps of

[0031] a) drawing blood from the patient into a blood sampler;

[0032...

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Abstract

The present invention relates to blood sampler and the preparation of blood samples that can be used for not only for blood gas, basic metabolic panel parameter analysis but also for a platelet countand / or white blood count, such as a 3-diff or 5-diff. The blood samples comprise at least one anticoagulant for the determination of blood gas and basic metabolic panel parameters and at least one anti-platelet agent.

Description

technical field [0001] The present invention relates to the field of diagnostic blood sample analysis. Background technique [0002] Rapidly performing blood tests are the mainstay of diagnosing and treating acute illnesses. Oxygenation status and acid-base balance are determined by arterial blood gas (BG) analysis and form a core part of modern evidence-based therapeutic algorithms in intensive care. Additionally, devices intended for intensive care testing are able to assess, for example, electrolytes, kidney function (creatinine), inflammation (C-reactive protein), and cardiac biomarkers. [0003] A basal metabolic panel (BMP) is used to check the condition of a person's kidneys and their electrolyte and acid / base balance, as well as their blood sugar levels, all of which are related to a person's metabolism. BMPs can also be used to monitor hospitalized patients and people with certain known conditions such as hypertension and hypokalemia. [0004] In addition, white ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/38
CPCG01N1/38G01N33/86G01N33/80A61P9/08A61K31/727B01L3/00A61B5/145G01N33/4925
Inventor M.A.布克哈特
Owner RADIOMETER AS
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