An anti-aging and repairing skin care composition and essence milk containing symbiotic bacteria combination fermented product and its preparation method and application

A combined fermentation and skin repair technology, applied in the directions of medical preparations containing active ingredients, preparations for skin care, pharmaceutical formulas, etc. Light irradiation, saccharification and other problems, to achieve good free radical scavenging effect, promote growth and collagen production, and stimulate the effect of skin immunity

Active Publication Date: 2021-08-17
广州一一生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, CN105662942A discloses a composition for maintaining skin moisture and anti-oxidation and its preparation method. The composition includes the following components in parts by weight: 400-2000 parts of fish collagen peptide, 50-100 parts of grape seed extract, 50-200 parts of sealwort extract, 300-500 parts of seabuckthorn extract, 100-500 parts of acai fruit powder, 6679-8329 parts of purified water, 1 part of sweetener, 20 parts of essence; the preparation prepared from the composition It is a compound preparation, has no toxic side effects, and can protect human skin from free radicals, but at the same time, the composition can only play a certain role in anti-oxidation, and cannot solve other problems such as light irradiation and saccharification that cause exogenous skin aging
CN109568161A discloses a method for preparing a composition with anti-glycation and anti-aging properties. The composition includes phase A and phase B, wherein phase A includes: 0.1 part of sclerotinia, 2 parts of 1.3 butanediol, 1 part of glycerin 87.75 parts of water; Phase B includes: 5 parts of apple fruit cell culture extract, 2 parts of glycerol glucosin, 5 parts of water, 5 parts of nicotinamide, 5 parts of glycerin, 5 parts of caprylyl glycol, and 5 parts of xanthan gum part, 5 parts of Danshen extract; the composition can eliminate glycated protein, reduce uneven skin tone and yellowish phenomenon, and can be used in mask essence, essence and lotion cream, but the anti-glycation effect of the composition The effect is not ideal, and the anti-glycation active ingredients are difficult to be absorbed by the skin to maximize their effect
CN110236965A discloses an anti-blue light skin care cosmetic and its preparation method. The anti-blue light skin care cosmetic includes an anti-blue light composition, and the composition includes the following components: 2-6% carotene, 2-4% camellia extract and 1% to 4% of saffron extract; the composition has strong blue light filtering ability and can block the damage of blue light to the skin, but the composition only plays a role against the specific skin aging inducement of blue light, and cannot solve the problem of skin aging caused by blue light. Free radical oxidation, glycation and other problems of natural aging
[0004] It can be seen that the existing skin care products have the problem of single efficacy, and their formulas are designed only for one of the many skin aging causes such as oxidation, saccharification or blue light irradiation, which cannot meet the comprehensive needs of skin aging; In fact, skin aging does not originate from a single environmental effect, but the result of multiple internal and external factors.

Method used

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  • An anti-aging and repairing skin care composition and essence milk containing symbiotic bacteria combination fermented product and its preparation method and application
  • An anti-aging and repairing skin care composition and essence milk containing symbiotic bacteria combination fermented product and its preparation method and application
  • An anti-aging and repairing skin care composition and essence milk containing symbiotic bacteria combination fermented product and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0097] This preparation example provides a symbiotic bacteria combination fermentation product I, the preparation method is as follows:

[0098] (1) 33.11g of rice, 33.11g of millet seeds, 0.66g of ginseng, 16.56g of macroalgae and 16.56g of raspberry are pulverized, then mixed with 180g of water, filtered with 80 mesh filter cloth to obtain the fermentation liquid, and heated at 100°C Under heating for 20min for sterilization;

[0099] (2) Utilize arginine to adjust the pH of the sterilized fermented liquid to be 4.5, place it in a seed tank, inoculate 4g of yeast and 2g of lactobacillus, in 5m 3 / h / 50L aeration, under 150rpm stirring and rotation, culture at 30°C for 22h;

[0100] (3) Then add arginine to adjust the pH to 6.5, add 12g of Schizophyllum, 3 / h / 50L aeration, under 150rpm stirring and rotation, culture at 30°C for 22h;

[0101] (4) Finally, use arginine to adjust the pH to 8.0, add 6g of Thermus thermophilus, and 3 / h / 50L ventilation, stirring and rotating at...

preparation example 2

[0105] This preparation example provides a symbiotic bacteria combination fermentation product II, the preparation method is as follows:

[0106] (1) 39.74g rice, 26.49g millet seeds, 0.66g ginseng, 19.87g macroalgae and 13.24g raspberry are pulverized, 200g water is added thereto, and then filtered with 80 mesh filter cloth to obtain the fermented liquid, and Heat at ℃ for 20min for sterilization;

[0107] (2) Utilize arginine to adjust the pH of the sterilized fermented liquid to be 5.0, place it in a seed tank, inoculate 4g of yeast and 2g of lactobacillus, in 5m 3 / h / 50L aeration, with 200rpm stirring and rotation, culture at 35°C for 20h;

[0108] (3) Then add arginine to adjust the pH to 6.0, add 12g of Schizophyllum, 3 / h / 50L aeration, with 200rpm stirring and rotation, culture at 35°C for 20h;

[0109] (4) Finally, use arginine to adjust the pH to 8.0, add 6g of Thermus thermophilus, and 3 / h / 50L ventilation, stirring and rotating at 200rpm, culture at 40°C for 20h...

Embodiment 1～6

[0125] An anti-aging and repairing skin care composition, the specific components are shown in Table 1, and the dosage unit of each component is "parts by weight".

[0126] Table 1

[0127]

[0128]

[0129] The preparation method is as follows:

[0130] Add tocopheryl acetate, methylsilanol hydroxyproline aspartate and water into the vacuum emulsification pot according to the formula, disperse homogeneously at 60°C, then cool down to 45°C, then add symbiotic bacteria Combination of fermented product, decarboxylated carnosine, palmitoyl pentapeptide-4, tocopheryl acetate, buddha extract, resveratrol, pomegranate fruit extract, narcissus bulb extract, flavescens root extract, licorice The root extract, the root extract of Scutellaria baicalensis and nicotinamide are evenly dispersed, filtered and discharged with a 200-mesh filter cloth to obtain the anti-aging and repairing skin care composition.

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Abstract

The present invention provides an anti-aging and repairing skin care composition containing fermented products of symbiotic bacteria combination, essence milk and its preparation method and application. Palmitoyl pentapeptide‑4, tocopheryl acetate, Budisma japonica extract, resveratrol, pomegranate fruit extract and narcissus bulb extract; the symbiotic bacteria of the symbiotic bacteria combination fermentation product include Schizophyllum, A combination of Thermus thermus, saccharomyces and Lactobacillus; the fermented material of the symbiotic bacteria combination fermentation product includes a combination of rice, millet seeds, ginseng, macroalgae and raspberries. The anti-aging and repairing skin care composition can regulate and repair anti-aging pathways such as anti-oxidation, anti-glycation, anti-blue light, and promotion of collagen synthesis through the synergistic compounding of effective active ingredients such as symbiotic bacteria combination fermentation products, Thereby protecting the vitality of cells, so that the skin has the ability to resist exogenous environmental factors.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an anti-aging and repairing skin care composition containing fermented products of symbiotic bacteria combination, essence milk and its preparation method and application. Background technique [0002] Aging is one of the most basic natural laws in the biological world. Skin aging is mainly divided into endogenous aging and exogenous aging. Among them, endogenous aging is natural aging, which is caused by the internal factors of the body, mainly manifested as wrinkles and sagging in both exposed and non-exposed parts of the skin. Exogenous aging is mainly caused by environmental factors, including light radiation, smoking, and exposure to harmful chemicals; because sunlight is the main factor leading to skin aging among environmental factors, exogenous aging of the skin is also called skin aging. photoaging. The characteristics of skin photoaging only appear on th...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/9794A61K8/9789A61K8/9728A61K8/67A61K8/64A61K8/34A61K8/9711A61K8/58A61Q19/08A61Q19/00
CPCA61K8/347A61K8/585A61K8/64A61K8/675A61K8/678A61K8/99A61K2800/592A61K2800/5922A61K2800/782A61K2800/85A61Q19/00A61Q19/08A61K8/9711A61K8/9728A61K8/9789A61K8/9794
Inventor 龚德明温伟红莫霖霭徐洁琼
Owner 广州一一生物技术有限公司
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