Stress administration device and drug storage core layer

Abstract

The present invention involves a pressure supply device and drug storage core layer, which is suitable for external use and meridian skin administration.It has a negative pressure shell. On one side of the negative pressure shell is a closed shell equipped with a negative pressure exhaust port, and the other side is the open end. On one side of the open end of the negative pressure shell, at least one cross -section line is installed.For 0 to multiple concave types, the dating end or a cross -section line is 0 to multiple concave feed on the middle of the administration plate, and the cross -side side is equipped with an cross -section of 0 to multiple matching convex types.Drug storage core layer.The beneficial effect of the present invention is the increase in the surface area of the stratum corneum, thinning thickness, small skin damage, uniform pressure on dose, large administration, deep administration, large administration area, uniform distribution of administration, uniform distribution of administration, gradually improving, gradually given.Drug processes, low dose particle size requirements, large dosage range, low cost, and simple operation.

Description

technical field [0001] The invention relates to a pressure drug delivery device and a drug storage core layer, which are suitable for external use and percutaneous drug delivery. Background technique [0002] The traditional external and transdermal administration methods are ordinary external application, micro-needle external application and micro-needle injection. Although ordinary external application is low in cost and simple in operation, the absorption efficiency is not high, the bioavailability of the drug is not high, and the therapeutic index of the drug is not high; Microneedle external application and microneedle injection improve absorption efficiency, drug bioavailability, and drug therapeutic index, but have high cost, complicated operation, general uniformity of drug distribution, and damage to the stratum corneum. SUMMARY OF THE INVENTION [0003] The purpose of the present invention is to provide a kind of stratum corneum that can increase the surface are...

AI Technical Summary

Problems solved by technology

[0002] Traditional external application and transdermal drug delivery methods are common external application, microneedle external application and microneedle injection. Although common external application is low in cost and easy to operate, its absorption efficiency is not high, the bioavailability of the drug is not high, and the therapeutic index of the drug is not high; Although microneedle external application and microneedle injection have improved absorption efficiency, drug bioavailability, and therapeutic index of drugs, they are costly, complicated to operate, generally uniform in drug distribution, and cause damage to the stratum corneum

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