Composition with anti-constipation effect, preparation method and application thereof
A composition and constipation technology, applied in the field of biomedicine, can solve problems such as unfavorable improvement of gastrointestinal motility, impact on appearance and taste, high incidence of abdominal distension, etc.
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Embodiment 1
[0110] Example 1 Composition and proportioning research of the composition of the present invention
[0111] Weigh required amounts of the first polymer and the second polymer according to Table 1, wherein the total number of parts of the first polymer and the second polymer is 40 parts, add 60 parts of water, stir and dissolve to prepare the composition.
[0112] A total of 130 patients with cancer chemotherapy-related constipation were selected, regardless of gender. The age range of the subjects was 40-60 years old. It was required that they had no intestinal diseases within one month and did not take antibiotics, microecological drinks or health care medicines.
[0113] 130 patients were randomly divided into 13 groups, 10 cases in each group. Among them, the 12th group is the experimental group, and the test patients take the composition A-L respectively, and the dosage is 2 times / day, each time 15g, for 14 consecutive days; the 13th group is the blank control group, and...
Embodiment 2
[0123] Example 2 Raw material ratio research experiment of the composition of the present invention
[0124] Weigh the required amount of the first polymer and the second polymer according to Table 2, the total number of parts of the first polymer and the second polymer is 40 parts, add 60 parts of water, stir and dissolve, and prepare the composition.
[0125] Select 100 test patients with constipation related to tumor chemotherapy, regardless of sex, the age range of the patients is 40-60 years old, the test patients have no intestinal diseases within 1 month, and have not taken antibiotics, probiotic drinks or health medicine.
[0126] 100 test patients were randomly divided into 10 groups, 10 cases in each group. Among them, group 9 is the test group, taking compositions 1-9 respectively, the dosage is 2 times / day, 15g each time, and taking for 14 consecutive days; group 10 is the blank control group, and the test patients take the same amount of Water without taking a...
Embodiment 3
[0135] Example 3 Sensory evaluation experiment of the composition of the present invention
[0136] A total of 90 patients aged 40-60 with constipation symptoms were selected, including 30 patients with constipation caused by cancer chemotherapy, 30 patients with chronic constipation and 30 patients with constipation caused by enteral nutrition.
[0137] 90 subjects took the composition 3 of the present invention respectively, the dosage was 2 times / day, 15g each time, for 14 consecutive days. See Table 3 for the sensory evaluation test results of the composition of the present invention.
[0138] The sensory evaluation experiment of table 3 composition of the present invention
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[0140]
[0141] It can be seen from Table 3 that the composition of the present invention has good flavor and mouthfeel, suitable dosage, and is suitable for preventing and treating various types of constipation.
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