A traditional Chinese medicine spray film for treating prostatitis and preparation method thereof

A technology for spraying film and traditional Chinese medicine, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. It can solve the problems of repeated episodes of patients' illness, disputes in the process of diagnosis and treatment, etc., and achieve the effect of spraying Good, significant therapeutic effect, large drug loading effect

Active Publication Date: 2021-10-22
YANBIAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the etiology and pathogenesis of type III prostatitis have not been fully clarified, leading to great controversy in its diagnosis and treatment process. burden

Method used

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  • A traditional Chinese medicine spray film for treating prostatitis and preparation method thereof
  • A traditional Chinese medicine spray film for treating prostatitis and preparation method thereof
  • A traditional Chinese medicine spray film for treating prostatitis and preparation method thereof

Examples

Experimental program
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preparation example Construction

[0032] In the present invention, the preparation method of the Chinese medicine spray film agent preferably includes the following steps: (1) After mixing the lactic acid and distilled water in the raw material of the Chinese medicine liquid and the raw material of the film-forming agent respectively, the first lactic acid solution and the second lactic acid solution are obtained. Lactic acid solution;

[0033] (2) dissolving the bear bile powder, euphorbia extract, Scutellaria barbata extract and fennel extract in the first lactic acid solution to obtain a traditional Chinese medicine liquid;

[0034] (3) After mixing the clove oil and glycerin, an oily solution is obtained;

[0035] (4) After mixing the oily solution, chitosan and the second lactic acid solution, a film-forming agent is obtained;

[0036] (5) Stir and mix the Chinese medicine liquid and the film-forming agent to obtain a Chinese medicine film-spraying agent.

[0037] In the present invention, the first lac...

Embodiment 1

[0044] 1. Preparation of traditional Chinese medicine liquid: Accurately weigh 1.5mL of lactic acid, and set the volume to 50mL to obtain a 3% lactic acid solution. Accurately weigh 0.02g of bear bile powder, 0.2g of Euphorbia extract, 0.6g of Scutellaria barbata extract and 0.12g of fennel extract, add them into 3% lactic acid solution, stir with a magnetic stirrer for 30-40min until uniform, and obtain Chinese medicinal liquid.

[0045] 2. Preparation of film-forming agent: Accurately weigh 0.06 mL of clove oil and 1 mL of glycerin. Add clove oil to glycerin and stir evenly to obtain solution A, which is left to stand for use. Accurately weigh 1.5mL of lactic acid and dilute to 50mL to obtain a 3% lactic acid solution. Accurately weigh 1g of chitosan, add it into the prepared 3% lactic acid solution, stir on a magnetic stirrer, at the same time slowly add solution A, stir for 30-40min until evenly stirred, and obtain the film-forming agent.

[0046] 3. Preparation of trad...

Embodiment 2

[0048] Effect of lactic acid concentration on chitosan film formation:

[0049] Except that the concentration of lactic acid is different, all the other conditions are the same as the preparation of the film-forming agent in Example 1: respectively setting the concentration of lactic acid as 1%, 1.5%, 2%, 2.5%, 3%, and 3.5% to investigate the effect of the concentration of lactic acid on the film-forming properties , the results are shown in Table 1 and Figure 1~6 As shown, among them, figure 1 The film-forming effect when the concentration of lactic acid is 1%, figure 2 The film-forming effect when the concentration of lactic acid is 1.5%, image 3 The film-forming effect when the concentration of lactic acid is 2%, Figure 4 The film-forming effect when the concentration of lactic acid is 2.5%, Figure 5 The film-forming effect at the concentration of 3% lactic acid, Figure 6 The film-forming effect when the concentration of lactic acid is 3.5%; and in Table 1, the s...

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Abstract

The invention provides a traditional Chinese medicine film-spraying agent for treating prostatitis, belonging to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine film-spraying agent of the present invention includes a traditional Chinese medicine liquid and a film-forming agent; the Chinese medicine liquid includes the following raw materials in parts by weight: 1 to 5 parts of bear bile powder, 5 to 10 parts of Euphorbia extract, Scutellaria barbata 20 to 40 parts of extract, 3 to 8 parts of fennel extract, 120 to 180 parts of lactic acid and 4500 to 5000 parts of distilled water; the weight ratio of the traditional Chinese medicine liquid and film-forming agent is (0.8 to 1.2): (0.8 to 1.2). The traditional Chinese medicine spray film agent of the present invention has the advantages of stable quality, good film-forming property, good spray effect, large drug loading capacity, no local irritation, medicine close to the skin after medication, good transdermal effect, long action time, easy to carry and use Convenient, easy to control the dosage and other advantages. It has been proved by clinical experiments that it has the functions of clearing away heat and detoxifying, promoting diuresis and treating stranguria, removing blood stasis and dampness, and nourishing the liver and kidney, and the therapeutic effect is remarkable.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine film-spraying agent for treating prostatitis and a preparation method thereof. Background technique [0002] Prostatitis is a common disease in urology, accounting for the first place in male patients under the age of 50 in urology. Prostate disease can be manifested as frequent urination, urgency, dysuria, hematuria, dysuria, urinary incontinence, bifurcation of urine line, dribbling after urination, increased frequency of nocturia, dribbling after urination or stool, which greatly affects the patient's health. Quality of Life. The National Institutes of Health (NIH) currently divides prostatitis into 4 types: Type I, acute bacterial prostatitis, type II, chronic bacterial prostatitis, type III, chronic prostatitis / chronic pelvic pain syndrome, and type IV For asymptomatic prostatitis. The main patho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K36/539A61K47/12A61K47/36A61K47/44A61P13/08A61K35/413
CPCA61K9/7015A61K35/413A61K36/235A61K36/47A61K36/539A61K47/12A61K47/36A61K47/44A61P13/08A61K2300/00
Inventor 郭建鹏才煜
Owner YANBIAN UNIV
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