Detection method of traditional Chinese medicine composition

Abstract

The invention provides a detection method of a traditional Chinese medicine composition preparation. The method comprises the following steps: determination conditions: using octadecyl silane bonds and silica gel as fillers; using acetonitrile-water (25-35): (65-75) as a mobile phase, and using an evaporative light scattering detector for detection, wherein the number of theoretical plates is notless than 4000 according to the astragaloside peak calculation; preparation of a reference substance solution: preparing an astragaloside reference substance, and dissolving the astragaloside reference substance in an organic solvent to obtain the reference substance solution; preparation of a test solution: preparing the traditional Chinese medicine composition preparation, and extracting same with the organic solvent to obtain the test solution; the determination method comprises the following steps: respectively sucking the reference substance solution and the test solution, injecting sameinto a liquid chromatograph, and determining the solutions.

Description

technical field [0001] The invention relates to a detection method of a traditional Chinese medicine composition, which belongs to the field of medicine. Background technique [0002] Allergic rhinitis (allergic rhinitis, AR) refers to the release of mediators (mainly histamine) mediated by IgE after exposure to allergens in atopic individuals, and there are a variety of immune active cells and cells Non-infectious inflammatory diseases of the nasal mucosa in which factors and other factors are involved. AR is one of the most common allergic diseases, and its incidence has shown an obvious upward trend in recent years, affecting about 10%-25% of the world's population, especially in industrially developed countries. It is conservatively estimated that there are more than 500 million AR patients worldwide. Telephone surveys in 11 central cities in my country show that the prevalence of AR is about 11%. AR can lead to many diseases and labor loss, and has become a global pu...

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly uses immunotherapy and drug therapy in the treatment of AR, and there are deficiencies: immunotherapy allergens are difficult to determine and the standards are difficult to agree on, slow onset, long course of treatment, unsuitable for persistence, and difficult to cure; drug treatments mainly include decongestants, Antihistamines, glucocorticoids, anticholinergics, mast cell stabilizers, leukotriene receptor antagonists, etc., mainly treat symptoms and relieve symptoms. Radical method

However, it mainly focuses on eliminating superficial syndromes, and does not comprehensively protect the human body's righteousness; the holistic and systematic understanding of the essence of pathogenesis is insufficient, and the level of understanding needs to be improved; the therapeutic effect is still lacking, and cannot meet clinical needs.

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