Microencapsulation preparation method of rhizoma coptidis, cortex phellodendri and berberis poiretii schneid crude extract

A crude extract and microencapsulation technology, applied in microcapsules, medical preparations containing active ingredients, digestive system, etc., can solve the problem of bitter taste affecting the feed intake rate of live pigs, and achieve masking of bad odor and control of intestinal bacteria. Group, easy to take effect

Inactive Publication Date: 2019-09-06
河南大华生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, pigs are animals whose sense of taste and smell are much higher than those of other livestock and poultry, and the taste masking agent usually has ...

Method used

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  • Microencapsulation preparation method of rhizoma coptidis, cortex phellodendri and berberis poiretii schneid crude extract
  • Microencapsulation preparation method of rhizoma coptidis, cortex phellodendri and berberis poiretii schneid crude extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A traditional Chinese medicine crude extract microcapsule, characterized in that it includes the following components in parts by weight: 3 parts of Coptidis rhizome, 3 parts of Cortex Phellodendri, 2 parts of Sangezhen, 25 parts of polyethylene glycol, 25 parts of glucose, 25 parts of mannitol 300 parts, 300 parts of fat powder, 300 parts of glyceryl monostearate, 300 parts of stearic acid.

[0037] The preparation method of the Chinese medicine crude extract microcapsules comprises the following steps:

[0038] SS01: Weigh each component according to the measurement, soak the weighed Chinese medicine raw materials in 5 times the weight of boiling water for 8 minutes, remove and let cool for 1 hour, cut into 5mm thick slices, and then put the Chinese medicine raw materials into thick slices Carry out ultrafine pulverization, pass through a 150-mesh sieve, and stir evenly to obtain a powdery mixture, which is set aside;

[0039] SS02: Soak the above mixture in deionize...

Embodiment 2

[0046] A traditional Chinese medicine crude extract microcapsule, characterized in that it includes the following components in parts by weight: 2 parts of Coptidis rhizome, 2 parts of Cortex Phellodendri, 2 parts of Sangezhen, 25 parts of polyethylene glycol, 25 parts of glucose, 25 parts of mannitol 300 parts, 300 parts of fat powder, 300 parts of glyceryl monostearate, 300 parts of stearic acid.

[0047]The preparation method of the Chinese medicine crude extract microcapsule is the same as that of Example 1.

Embodiment 3

[0049] A traditional Chinese medicine crude extract microcapsule, characterized in that it comprises the following components in parts by weight: 2 parts of Coptidis rhizome, 1 part of Cortex Phellodendri, 1 part of Sangezhen, 25 parts of polyethylene glycol, 25 parts of glucose, 25 parts of mannitol 300 parts, 300 parts of fat powder, 300 parts of glyceryl monostearate, 300 parts of stearic acid.

[0050] The preparation method of the Chinese medicine crude extract microcapsule is the same as that of Example 1.

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Abstract

The invention relates to a microencapsulation preparation method of rhizoma coptidis, cortex phellodendri and berberis poiretii schneid crude extract. The microencapsulation preparation method has theadvantages that rhizoma coptidis, cortex phellodendri and berberis poiretii schneid are used as the active components, the three traditional Chinese medicine materials are synergistic to allow the prepared microcapsules to have effects of increasing pig survival rate, controlling intestinal flora and preventing and treating diarrhea, and the microcapsules can also be used for treating diarrhea caused by Escherichia coli; by the microencapsulation method, the objectionable odor of the traditional Chinese medicine is masked effectively, pigs can easily take the microcapsules, and the treatmenteffect is improved greatly; the active components of the raw materials are effectively extracted through multiple methods such as superfine grinding, repeated soaking and decoction extraction, and specific parameters such as particle size and extraction time during preparation are scientifically regulated to effectively increase active component dissolution rate and bring the effects of the microcapsules into play.

Description

technical field [0001] The invention relates to the technical field of production of traditional Chinese medicine compositions, in particular to a microencapsulation preparation method of crude extracts of Coptidis Rhizome, Phellodendron Phellodendron and Sangee needles. Background technique [0002] Coptis chinensis, aliases: Weilian, Chuanlian, and chicken feet, is a perennial herb belonging to the Ranunculaceae family. Phellodendron, bark (de-cork) of Rutaceae Phellodendri Phellodendron and Chuan Phellodendron. Three needles, the dry roots of plants of the genus Berberis in the family Berberidaceae, such as Pseudo-porcupine thorn, Berberis chinensis, Xiaohuanglian thorn or Spoon-leaved Berberis, are also known as rhubarb, Muhuanglian, and thorny berberis among the people. In traditional Chinese medicine, the above three medicinal materials all have the effects of clearing away heat and dampness, purging fire and detoxifying. Adding the above three medicinal materials to...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/50A61P1/12A61P31/04
CPCA61K9/5031A61K36/29A61K36/718A61K36/756A61K2236/19A61K2236/331A61K2236/39A61K2236/51A61P1/12A61P31/04A61K2300/00
Inventor 徐天天徐其常
Owner 河南大华生物技术有限公司
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