Novel medical suture material and preparation method thereof

Abstract

The invention discloses a novel medical suture material and a preparation method thereof. The novel medical suture material is prepared from the following raw materials: yamamai silk, polyglycollide,collagen, chitosan, an antibacterial agent, acetic acid, urea, glycerin, pretreatment liquid and coagulation bath; the preparation method of the medical suture material comprises the following steps:preparation of a spinning solution; preparation of spinning thread; pretreatment of yamamai silk; preparation of an antibacterial agent solution; antibacterial coating treatment of spinning thread andyamamai silk respectively; braiding of the spinning thread and the silk; shaping of the braided wire, sterilizing, package, and acquisition of the novel medical suture material. The medical suture material has high tensile strength and good biocompatibility, and can be completely absorbed and degraded in biological tissues; the antibacterial effect is excellent and durable; the preparation process is short, the cost is low, the use is safe, and the production efficiency is high.

Description

Technical field [0001] The invention relates to the technical field of medical suture materials, in particular to a new medical suture material and a preparation method thereof. Background technique [0002] Medical suture materials include medical sutures, medical adhesives and surface suture materials. Medical sutures refer to special threads used for ligation, hemostasis, and tissue suturing during surgical operations. The quality level of the suture is essential to the success of the operation. Plays a vital role. With the advancement of human civilization and the advanced development of medicine, people have higher and higher requirements for medical sutures. An ideal medical suture should meet the following conditions: anti-microbial properties, speed up wound healing; good hand feel and strength High, with good flexibility, elasticity, knotty and knot retention; it is not easy to entangle medical rubber gloves, simplifying surgical operations; it should not be worn due to...

AI Technical Summary

Problems solved by technology

Polyamide sutures often appear in the form of monofilaments, with high strength, appropriate elasticity, and small tissue response. The disadvantages are difficult interface and poor knot retention. Polyamide sutures can be hydrolyzed in the body and can also be dissolved by protein-dissolving enzymes in the body. Widely used in skin surgery; polyester suture is the strongest non-absorbable suture, due to the large surface friction factor of the braided structure, the resistance is too large when knotting, so the surface of the suture is often coated to increase surface lubrication Polyester suture is suitable for cardiovascular surgery, plastic surgery, neurosurgery, microsurgery, ophthalmology, etc., especially for making artificial blood vessels, as well as grafting and suturing of large arteries, but the absorption period is long and it is easy to cause tissue infection ;Polypropylene suture has high strength, but low relative density, no water absorption, acid and alkali resistance, no degradation by tissues in the body, little tissue reaction, good chemical stability and biological inertness, polypropylene monofilament has a smooth surface, and can pass through when suturing The human tissue is smooth, but it is difficult to knot, and it is easy to get out of joints; sheep catgut is the earliest bioabsorbable suture, which is processed from collagen in sheep intestinal mucosa and bovine intestinal mucosa, and its tensile strength is low. Poor firmness, large tissue reaction caused by heterosexual protein, poor flexibility

Therefore, the current medical suture materials still have the problems of poor antibacterial properties, easy tissue infection, low tensile strength, and large tissue reaction.

Images