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Formula particle of Baiyun ginseng and preparation method thereof

A technology of formula granules and white clouds, which is applied in the directions of pharmaceutical formulas, medical preparations containing active ingredients, plant raw materials, etc., to achieve the effects of improving stability, easy storage, and easy industrialization.

Inactive Publication Date: 2019-03-29
JIANGXI GROUNDIONG PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no report about white ginseng formula granules and its preparation process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0019] The preparation method of white ginseng formula granules of the present invention comprises the following steps:

[0020] (1) Pulverizing the dried Baiyun ginseng medicinal material to obtain Baiyun ginseng medicinal material granules with a particle size of 40-100 mesh;

[0021] (2) Soak the Baiyun ginseng medicinal material granules in 3-5 times the volume of hot water;

[0022] (3) filter, the filter cake obtained is mixed with the ethanol-acetone mixed solution of 8-10 times of charging amount;

[0023] (4) Ultrasonic extraction for 2-3 times, filtering, and concentrating the filtrate under reduced pressure to obtain a concentrated solution with a relative density of 1.1-1.2;

[0024] (5) Mix the concentrated solution with pharmaceutically acceptable adjuvants, dry, collect the dry paste powder, pulverize it through an 80-mesh sieve, and place it in a mixing tank for mixing;

[0025] (6) Take Baiyun ginseng cream powder, granulate, and granulate the granules with ...

Embodiment 1

[0043] (1) Take 1 kg of dried Baiyun ginseng medicinal material, crush it to 80 mesh, soak it in hot water (70°C) with 4 times the feeding amount for 2 hours, filter it with 200 mesh stainless steel wire mesh, and mix the obtained filter cake with 9 times the feeding amount Ethanol-acetone mixed solution (ethanol: acetone = 10:12) was mixed, ultrasonically extracted 3 times at an ultrasonic frequency of 90kHz, each extraction was 45 minutes, filtered through a 200-mesh stainless steel mesh, and the filtrate was concentrated under reduced pressure to a relative density of 1.15 the concentrate;

[0044] (2) Add 100g of a mixture of starch, lactose and dextrin (the weight ratio of the three is 1:0.25:1) to the concentrated solution for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it in a mixing tank ;

[0045] (3) Take Baiyun ginseng cream powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh si...

Embodiment 2

[0047] (1) Take 1 kg of dried Baiyun ginseng medicinal material, crush it to 60 mesh, soak it in hot water (80°C) with 3 times the feeding amount for 3 hours, filter it with 200 mesh stainless steel wire mesh, and mix the obtained filter cake with 10 times the feeding amount Ethanol-acetone mixed solution (ethanol: acetone = 10:10) was mixed, ultrasonically extracted twice at an ultrasonic frequency of 125kHz, each extraction was 60 minutes, filtered through a 200-mesh stainless steel screen, and the filtrate was concentrated under reduced pressure to a relative density of 1.1 the concentrate;

[0048] (2) Add 80g of a mixture of starch, lactose and dextrin (the weight ratio of the three is 1:0.25:1) to the concentrated solution for mixing, freeze-dry, collect the dry cream powder, crush it through an 80-mesh sieve, and mix it in a mixing tank ;

[0049] (3) Take Baiyun ginseng paste powder, sieve and granulate, and granulate the granules with a 20-mesh sieve and a 50-mesh si...

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Abstract

The invention relates to the technical field of formula particle of traditional Chinese medicine and discloses a formula particle of Baiyun ginseng and a preparation method thereof. The method comprises six procedures as follows: (1) crushing the dried medical materials of Baiyun ginseng; (2) soaking the formula particles of Baiyun ginseng in 3-5 times the volume of hot water; (3) filtering and mixing up the filter cake and 8-10 times the feed quantity of ethanol and acetone mixed solution; (4) extracting 2-3 times in ultrasonic, filtering, decompressing and concentrating the filtrate; (5) mixing up the concentrated filtrate and accessories, drying, collecting dry paste powder, crushing more than 80 of visual screens, and placing in a mixing vessel to mix; and (6) taking Baiyun ginseng paste powder, pelletizing and 20 visual screens and 50 visual screens particles in whole grain being used, so that the formula particles of Baiyun ginseng are obtained. The formula particle of Baiyun ginseng made by the method is high in active component contend, and the particles are uniform in size.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine formula granules, in particular to white ginseng formula granules and a preparation method thereof. Background technique [0002] Traditional Chinese medicine formula granules are obtained by extracting, separating, concentrating, drying, granulating and packaging the whole ingredients of the medicinal materials through modern processing technology and pharmaceutical technology. They can be directly formulated and packaged without decoction. Granules for ingestion. Traditional Chinese medicine formula granules not only retain the active ingredients, indications and efficacy of traditional Chinese medicine decoction pieces, but also have the advantages that decoction pieces do not have, such as unified standard, stable curative effect, convenient carrying and easy adjustment. Over-the-counter supplements. [0003] Baiyun ginseng is a perennial herbaceous vine, the main compon...

Claims

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Application Information

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IPC IPC(8): A61K36/34A61K9/16
CPCA61K9/1652A61K36/34A61K2236/15A61K2236/331A61K2236/39A61K2236/51
Inventor 廖年生邹明明杨健平
Owner JIANGXI GROUNDIONG PHARM CO LTD
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