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Biological toothpaste for resisting helicobacter pylori

An anti-Helicobacter pylori, biological technology, applied in the direction of antibacterial drugs, dentistry, drug combination, etc., can solve the problems of increasing medical costs, low eradication, aggravating drug resistance of Helicobacter pylori, etc., to improve the body's resistance, The effect of preventing dental caries and eliminating oral Helicobacter pylori

Inactive Publication Date: 2019-03-22
泰州优克生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main transmission routes of Helicobacter pylori are fecal-oral, oral-oral and stomach-oral transmission; Helicobacter pylori in the cavity mainly exists in dental plaque, dental caries, oral mucosa, etc., so the oral cavity is a huge bacteria storage pool At present, antibiotic therapy is generally used for the treatment of Helicobacter pylori, which has obvious therapeutic effect on Helicobacter pylori in the stomach, but at the same time it will aggravate the drug resistance of Helicobacter pylori. If patients are repeatedly infected, their eradication will be reduced. It is getting lower and lower, and it increases the cost of medical care. It has almost no effect on the Helicobacter pylori in the oral cavity; looking at the transmission and infection routes of Helicobacter pylori, we should do a good job in preventing oral Helicobacter pylori and cleaning the mouth, especially Remove dental plaque, calculus, prevent and treat dental caries, repair oral mucosa, periodontal health care, minimize Helicobacter pylori storage areas

Method used

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  • Biological toothpaste for resisting helicobacter pylori
  • Biological toothpaste for resisting helicobacter pylori
  • Biological toothpaste for resisting helicobacter pylori

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]25 parts of sorbitol, 1.5 parts of sodium carboxymethyl cellulose, 2.5 parts of sodium lauryl sulfate, 13 parts of polyethylene glycol, 4 parts of calcium hydrogen phosphate, 20 parts of silicon dioxide, 0.3 parts of xylitol, cauliflower 1 part of eugenol, 0.5 part of eugenol, 0.5 part of tea tree essential oil, 0.3 part of lactoferrin, 1 part of probiotic, and deionized water to 100 parts.

Embodiment 2

[0035] 20 parts of sorbitol, 3 parts of sodium carboxymethyl cellulose, 4 parts of sodium lauryl sulfate, 8 parts of polyethylene glycol, 7 parts of calcium hydrogen phosphate, 25 parts of silicon dioxide, 0.7 parts of xylitol, cauliflower 4 parts of eugenol, 0.8 parts of eugenol, 0.3 parts of tea tree essential oil, 0.7 parts of lactoferrin, 5 parts of probiotics, and 100 parts of deionized water.

[0036] Test method: culture Helicobacter pylori strains in vitro, such as image 3 Test the survival rate of Helicobacter pylori in the reference group 1, reference group 2 and experimental group toothpaste at the same concentration.

[0037] Depend on image 3 and Figure 4 From the experimental data, it can be concluded that under the same concentration, the toothpaste of the experimental group has a dominant inhibitory effect on Helicobacter pylori.

Embodiment 3

[0039] 15 parts of sorbitol, 1 part of sodium carboxymethyl cellulose, 1 part of sodium lauryl sulfate, 5 parts of polyethylene glycol, 2 parts of calcium hydrogen phosphate, 15 parts of silicon dioxide, 0.1 part of xylitol, cauliflower 0.5 part of eugenol, 0.1 part of eugenol, 0.1 part of tea tree essential oil, 0.1 part of lactoferrin, 1 part of probiotic, and deionized water to 100 parts.

[0040] Implementation method: use in vitro culture of Helicobacter pylori strains to test the survival rate of Helicobacter pylori under different toothpaste concentrations.

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Abstract

The invention provides biological toothpaste for resisting helicobacter pylori, and relates to the field of medical application. The biological toothpaste comprises the following substances in parts by weight: 25 parts of sorbitol, 1.5 parts of sodium carboxymethyl cellulose, 2.5 parts of sodium dodecyl sulfate, 13 parts of polyethylene glycol, 4 parts of calcium hydrogen phosphate, 20 parts of silicon dioxide, 0.3 part of xylitol, 1 part of broccoli essence, 0.5 part of eugenol, 0.5 part of tea tree essential oil, 0.3 part of lactoferrin, 1 part of probiotics and the balance of deionized water. In the biological toothpaste provided by the invention, the broccoli essence, lactoferrin and eugenol play a role in killing helicobacter pylori and cariogenic bacteria, the tea tree essential oilcan remove dental plaques and freshen breath, the xylitol can prevent dental caries, and the probiotics can balance oral floras. The raw materials are organically combined to prepare the toothpaste, which can play a role in eliminating oral helicobacter pylori, preventing dental caries and balancing oral floras, thereby realizing the purpose of the invention. The biological toothpaste provided bythe invention is simple to manufacture, is used as a daily necessity, is convenient and quick to use, economical and applicable, and good for long-term use, prevents and treats helicobacter pylori andcariogenic bacteria in an oral cavity, and keeps the oral cavity healthy.

Description

technical field [0001] The invention belongs to the field of medical application, in particular to a biological toothpaste for resisting Helicobacter pylori. Background technique [0002] Helicobacter pylori (Helicobacter pylori) is referred to as Hp. It is a kind of microaerophilic helicobacter with unipolar, multi-flagellate, blunt-rounded end segment and spiral bending, which colonizes in oral cavity, gastric mucosa and other areas. It is an infectious pathogenic bacteria; Studies in the past ten years have proved that Hp infection is the main pathogenic factor of infectious halitosis, oral ulcers, chronic active gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer; 1994 World Health Organization / International The Cancer Research Institute (WHO / IARC) defines Helicobacter pylori as a Class I carcinogen; the infection rate in my country is 50% to 56%, and due to the unique habit of eating together and family structure in China...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/24A61K8/25A61K8/34A61K8/46A61K8/64A61K8/73A61K8/86A61K8/92A61K8/9789A61P1/02A61P31/04A61Q11/00
CPCA61K8/345A61K8/24A61K8/25A61K8/347A61K8/463A61K8/64A61K8/731A61K8/86A61K8/922A61K8/9789A61K8/99A61P1/02A61P31/04A61Q11/00
Inventor 唐正尧唐静
Owner 泰州优克生物科技有限公司
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