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Process for preparing polygonum multiflorum-aloe bowel-relaxing capsule

A preparation process, a laxative technology of Shouhui, which is applied in the direction of capsule delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., and can solve problems such as shortening the disintegration time limit

Active Publication Date: 2019-03-15
LUNAN PHARMA GROUP CORPORATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the follow-up research and development process, it was found that although the performance of Shouhui Laxative Capsules met the standards of the Pharmacopoeia, there is still room for improvement, for example, the water content can be further reduced, and the disintegration time limit can be further shortened

Method used

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  • Process for preparing polygonum multiflorum-aloe bowel-relaxing capsule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0086] Embodiment 1: a kind of Shouhui Laxative Capsules, the content and preparation process are as follows:

[0087] 75 parts by weight of donkey-hide gelatin, 160 parts by weight of aloe vera, 120 parts by weight of Polygonum multiflorum, 140 parts by weight of cassia seed, 75 parts by weight of medlar, 50 parts by weight of Atractylodes macrocephala, 120 parts by weight of Citrus aurantium, and 50 parts by weight of ginseng.

[0088] The preparation process is as follows:

[0089] a. Fractionation and purification process

[0090] 1), grind ginseng and donkey-hide gelatin into fine powder under vacuum state, pass through 80 mesh sieve, set aside;

[0091] 2), Citrus aurantium, Semen Cassiae and Atractylodes Rhizoma Atractylodes are crushed and passed through an 80-mesh sieve, added 75% ethanol to reflux for extraction twice, and the filtrates are combined for subsequent use;

[0092] 3) Polygonum multiflorum and aloe were soaked in water for 2 hours, and the volatile oil...

Embodiment 2

[0102] Embodiment 2: a kind of Shouhui Laxative Capsules, the content and preparation process are as follows:

[0103] 75 parts by weight of donkey-hide gelatin, 160 parts by weight of aloe vera, 120 parts by weight of Polygonum multiflorum, 140 parts by weight of cassia seed, 75 parts by weight of medlar, 50 parts by weight of Atractylodes macrocephala, 120 parts by weight of Citrus aurantium, and 50 parts by weight of ginseng.

[0104] The preparation process is as follows:

[0105] a. Fractionation and purification process

[0106] 1), grind ginseng and donkey-hide gelatin into fine powder under vacuum state, pass through 80 mesh sieve, set aside;

[0107] 2), Citrus aurantium, Semen Cassiae and Atractylodes Rhizoma Atractylodes are crushed and passed through a 80-mesh sieve, added 65% ethanol for reflux extraction twice, and the filtrates are combined for subsequent use;

[0108] 3) Polygonum multiflorum and aloe were soaked in water for 0.5 hours, and the volatile oil w...

Embodiment 3

[0118] Embodiment 3: a kind of Shouhui Laxative Capsules, the content and preparation process are as follows:

[0119] 75 parts by weight of donkey-hide gelatin, 160 parts by weight of aloe vera, 120 parts by weight of Polygonum multiflorum, 140 parts by weight of cassia seed, 75 parts by weight of medlar, 50 parts by weight of Atractylodes macrocephala, 120 parts by weight of Citrus aurantium, and 50 parts by weight of ginseng.

[0120] The preparation process is as follows:

[0121] a. Fractionation and purification process

[0122] 1), grind ginseng and donkey-hide gelatin into fine powder under vacuum state, pass through 80 mesh sieve, set aside;

[0123]2), Citrus aurantium, Semen Cassiae and Atractylodes Rhizoma Atractylodes are crushed and passed through an 80-mesh sieve, added 75% ethanol to reflux for extraction twice, and the filtrates are combined for subsequent use;

[0124] 3) Polygonum multiflorum and aloe were soaked in water for 5 hours, and the volatile oil ...

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Abstract

The invention belongs to the field of traditional Chinese medicines and particularly discloses the improvement on a process for preparing polygonum multiflorum-aloe bowel-relaxing capsules. The polygonum multiflorum-aloe bowel-relaxing capsules are prepared from the following traditional Chinese medicine components in parts by weight: 75 parts of donkey-hide gelatin, 160 parts of aloes, 120 partsof polygonum multiflorum, 140 parts of cassia seeds, 75 parts of lycium barbarum, 50 parts of atractylodes macrocephala, 120 parts of immature bitter oranges and 50 parts of ginseng. According to theprocess, different preparation processes are adopted for different traditional Chinese medicines, contents of effective components are ensured, meanwhile, conventional auxiliary materials and amount ratios are screened, a polygonum multiflorum-aloe bowel-relaxing preparation process is improved, and the preferred preparation process has various property indexes such as water contents, disintegration time limits and dissolution rates which all meet requirements of the Chinese Pharmacopoeia, and is applicable to industrial large-scale production.

Description

technical field [0001] The invention relates to a preparation process of Shouhui laxative capsules, belonging to the field of traditional Chinese medicines. Background technique [0002] Shouhui Laxative Capsules, selected authentic medicinal materials, is a national patented formula for laxative detoxification, weight loss and fat reduction. The whole prescription is composed of 8 Chinese herbal medicines. It is targeted for the treatment of functional constipation. The TCM syndrome belongs to deficiency of both qi and yin and accumulation of toxins. The tongue is red and tender or pale, the tongue coating is white or greasy, and the pulse is thready or slippery. It has the effects of purging turbidity and laxative, nourishing yin and replenishing qi, and comprehensively improves gastrointestinal function. [0003] Chinese patent CN100453105C discloses a composition and preparation method with laxative detoxification, weight loss and lipid-lowering functions. The product ...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/886A61K9/48A61K47/69A61K47/10A61P1/10A61K35/36
CPCA61K36/896A61K47/6951A61P1/10A61K9/1641A61K36/258A61K36/284A61K36/482A61K36/704A61K36/752A61K36/815A61K36/886A61K2236/333A61K2236/331A61K2236/53A61K2236/51A61K2236/39A61K2300/00
Inventor 程国良杨本官
Owner LUNAN PHARMA GROUP CORPORATION
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