External plant-sourced itching-relieving antiphlogistine and preparation method thereof

An anti-inflammatory ointment and plant-sourced technology, applied in the direction of plant raw materials, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of easy loss of biological activity, toxicity, and low cure rate, and achieve antibacterial The effect of anti-inflammatory and anti-itching is remarkable, the process is simple, and the operation is simple and reasonable.

Inactive Publication Date: 2018-11-16
INST OF APPLIED CHEM JIANGXI ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, commonly used antipruritic products are mainly antipruritic drugs for external use, most of which are ointments and sprays containing hormones and anti-allergic ingredients. Strong antipruritic and side effects, so it is not suitable for long-term use; most of the antipruritic drugs based on traditional Chinese medicine have the disadvantages of complex prescriptions, expensiv...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The camphor tree extract is prepared according to the following process: the raw material is a mixture of one or more of the roots, stems, leaves, skins, fruits and seeds of the camphor tree; 50~90% ethanol aqueous solution is the extraction solvent, the ratio of material to liquid is 1g:5~20mL, the extraction temperature is normal temperature, and the conditions of 100~300W ultrasonic extraction for 2~4 hours are used for leaching and filtering, and the filtrate is at a steam pressure of 0.01~0.1 Under the conditions of kPa, vacuum degree of 0.08-0.09Mpa, and temperature of 60-85°C, vacuum distillation is carried out for 10-30 minutes until there is no alcohol smell, and then dried to a moisture content of less than 5% to obtain camphor tree extract.

[0027] The lotus husk extract is prepared according to the following process: after crushing and sieving the raw lotus husks (80 mesh to 150 mesh), a volume fraction of 50 to 90% ethanol aqueous solution with a pH value o...

Embodiment 2

[0035] The preparation processes of camphor tree extract, Panax notoginseng extract, broad-leaved ten great achievements extract, basil extract, and lotus husk extract are the same as those in Example 1.

[0036] A plant-derived antipruritic and anti-inflammatory ointment for external use, which is prepared in parts by weight from the following raw materials: 1.5 parts of camphor tree extract, 4 parts of Periflora Radix Notoginseng extract, 6 parts of broad-leaved Ten Great Merit Extract, and basil extract 5 parts, lotus husk extract 6 parts, 120 parts white petrolatum, 100 parts stearic acid and 230 parts glycerin.

[0037] A preparation method for external use of plant source antipruritic and anti-inflammatory ointment. 5 parts of the extract, 6 parts of lotus husk extract, 120 parts of white vaseline, 100 parts of stearic acid and 230 parts of glycerin are mixed and stirred to form a paste, to obtain a plant-derived antipruritic anti-inflammatory paste.

Embodiment 3

[0039] The preparation processes of camphor tree extract, Panax notoginseng extract, broad-leaved ten great achievements extract, basil extract, and lotus husk extract are the same as those in Example 1.

[0040] A plant-derived antipruritic and anti-inflammatory ointment for external use, which is prepared by weight of the following raw materials: 2 parts of camphor tree extract, 5 parts of Periflora Radix Notoginseng extract, 8 parts of broad-leaved Ten Great Works Extract, and basil extract 6 parts, lotus husk extract 6 parts, 200 parts white petrolatum, 100 parts stearic acid and 300 parts glycerin.

[0041] A preparation method for external use of plant-derived antipruritic and anti-inflammatory ointment, comprising the steps of: extracting 2 parts of camphor tree extract, 5 parts of Panax notoginseng extract, 8 parts of broad-leaved ten great merit extract, and basil according to the weight ratio of the formula 6 parts of the extract, 6 parts of lotus husk extract, 200 p...

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PUM

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Abstract

The invention discloses external plant-sourced itching-relieving antiphlogistine. The antiphlogistine is prepared from the following raw materials in parts by weight: 1-4 parts of camphor tree extract, 3-8 parts of folium gynurae procumbens extract, 5-9 parts of folium mahonia bealei extract, 4-10 parts of basil extract, 5-11 parts of lotus seedpod extract, 100-200 parts of albolene, 100-200 partsof stearic acid and 200-300 parts of glycerol, wherein the camphor tree extract, the folium gynurae procumbens extract, the folium mahoniae bealei extract, the basil extract, the lotus seedpod extract, the albolene, stearic acid and the glycerol are mixed and stirred uniformly to form paste so as to obtain the plant-sourced itching-relieving antiphlogistine. The antiphlogistine adopts pure natural plant raw materials and has the advantages of being simple in formula, extensive in sources, safe and mild to human bodies, free of toxic and side effects, capable of being used for a long time, capable of better according with a natural and healthy consumption concept and capable of achieving obvious effects of resisting bacteria, diminishing inflammation and relieving itching.

Description

technical field [0001] The invention belongs to the technical field of external ointment, and in particular relates to a plant source antipruritic and anti-inflammatory ointment for external use and a preparation method thereof. Background technique [0002] With changes in the environment, air, living habits, work pressure, etc., itching, redness, and inflammation of the skin have become a common disease that plagues most people, especially in hot and humid environments. Pain, numbness, burning, etc., will continue to scratch when itching, causing skin ulceration and extra scratches. It seriously affects people's normal life and study, and has a great impact on people's health. [0003] At present, the commonly used antipruritic products are mainly topical antipruritic drugs, most of which are ointments and sprays containing hormones and anti-allergic ingredients. It is not suitable for long-term use due to strong side effects and strong side effects; most antipruritic dr...

Claims

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Application Information

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IPC IPC(8): A61K36/62A61K9/06A61P17/04A61P29/00
CPCA61K9/0014A61K9/06A61K36/28A61K36/29A61K36/53A61K36/54A61K36/62A61K47/12A61K2236/333A61K2236/51A61P17/04A61P29/00A61K2300/00
Inventor 吴磊胡居吾熊伟付建平韩晓丹王慧宾
Owner INST OF APPLIED CHEM JIANGXI ACAD OF SCI
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