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A kind of golden lotus coated effervescent tablet and preparation method thereof

A technology of nasturtium and effervescent tablets, applied in sugar-coated pills, pharmaceutical formulas, medical preparations with non-active ingredients, etc., can solve problems affecting the appearance and effectiveness of effervescent tablets, affecting the body's acid-base balance, and easy disintegration, etc. problem, to achieve the effect of reasonable acid-base dosage ratio, complete and smooth appearance, and short disintegration time

Active Publication Date: 2021-08-06
GUANGDONG ROC MEDICINAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the Trollius effervescent tablet prepared by this invention mixes alkaline disintegrating agent sodium carbonate and acidic disintegrating agent citric acid and syringic acid together, and it is easy to disintegrate after absorbing moisture, which affects the appearance and effectiveness of the effervescent tablet, and After the effervescent tablet dissolves, the pH of the solution is <4.5, and long-term use can easily affect the acid-base balance of the body

Method used

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  • A kind of golden lotus coated effervescent tablet and preparation method thereof
  • A kind of golden lotus coated effervescent tablet and preparation method thereof
  • A kind of golden lotus coated effervescent tablet and preparation method thereof

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Effect test

Embodiment 1

[0029] Embodiment 1 A kind of golden lotus flower coated effervescent tablet

[0030] A kind of golden lotus coated effervescent tablet, comprising coating layer, acid layer, golden lotus layer and alkali layer successively, described acid layer is made by 0.75 part of anhydrous citric acid; Described golden lotus layer is made of 0.45 part of golden lotus Lotus flower extract, 0.025 part of aspartame and 0.005 part of xylitol are made; Described alkaline layer is made of 0.4 part of alkaline agent, and described alkaline agent is by mass ratio 1:1.5 by calcium carbonate and sodium bicarbonate Proportional composition; Described coating layer is made of coating liquid, and described coating liquid is mainly dissolved in 75% ethanol by 6% konjac glucomannan, 0.3% sorbitol, 0.5% sodium pyrophosphate and 0.03% tartrazine solution is made.

[0031] Preparation steps:

[0032] S1. Preparation of nasturtium extract: take the picked and cleaned nasturtium in the extraction tank, ...

Embodiment 2

[0036] Embodiment 2 A kind of golden lotus flower coated effervescent tablet

[0037] The difference between embodiment 2 and embodiment 1 is that the mass ratio of calcium carbonate and sodium bicarbonate is 1:2, all the other parameters and operation refer to embodiment 1.

Embodiment 3

[0038] Embodiment 3 A kind of troussus flower coated effervescent tablet

[0039] The difference between embodiment 3 and embodiment 1 is that the mass ratio of calcium carbonate and sodium bicarbonate is 1:1, all the other parameters and operation refer to embodiment 1.

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Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a nasturtium coated effervescent tablet and a preparation method thereof. The Trollius coated effervescent tablet sequentially comprises a coating layer, an acid layer, a Trollium layer and an alkali layer; the acid layer is mainly made of 0.6-0.8 parts of anhydrous citric acid; the Trollius layer is mainly made of 0.1-0.5 parts of nasturtium extract, 0.01-0.035 parts of aspartame and 0.002-0.010 parts of xylitol; the alkali layer is mainly made of 0.30-0.45 parts of alkali agent, and the alkali agent is made of calcium carbonate and sodium bicarbonate according to the mass ratio of 1: (1 ~ 2). The Nasturtium Coated Effervescent Tablet separates acid-base disintegrants to avoid hygroscopic disintegration of the effervescent tablet. It has good stability and can be disintegrated and completely dissolved within 2 minutes. The pH of the dissolved solution is between 4.5 and 6.0. Reduce the impact of long-term use of effervescent tablets on the acid-base balance in the body.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a nasturtium coated effervescent tablet and a preparation method thereof. Background technique [0002] Nasturtium is a perennial herb of the family Ranunculaceae, which is rich in nutrients, such as flavonoids orientin, vitexin, alkaloids, resins, palmitic acid, coumarin and its glycosides, polysaccharides, Volatile oils, tannins, various alcohol compounds, etc. Tsunflower is used as medicine with flowers, bitter in taste, cool in nature, has heat-clearing and detoxifying, antibacterial and anti-inflammatory functions, and has a strong inhibitory effect on pneumococcus, Pseudomonas aeruginosa, catarrhal bacteria, etc.; acute and chronic tonsillitis, pharyngitis, acute otitis media, Conjunctivitis and upper respiratory tract infection and other diseases have a significant therapeutic effect. [0003] Chinese patent application CN1559517A disc...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/46A61K9/24A61K9/36A61K36/71A61K47/02A61K47/12A61P31/04A61P11/04A61P27/16A61P27/02A61P11/00A61K133/00
CPCA61K9/0007A61K9/2009A61K9/2013A61K9/2086A61K9/2813A61K9/286A61K36/71A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P11/00A61P11/04A61P27/02A61P27/16A61P31/04
Inventor 高旭华高仪王一飞廖晓凤
Owner GUANGDONG ROC MEDICINAL TECH CO LTD
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