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Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof

A drug and composition technology, applied in the field of traditional Chinese medicine, can solve problems such as too many injections and ineffective Chinese and Western medicines

Inactive Publication Date: 2018-09-07
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are only a small number of single preparations and compound preparations composed of two effective parts in traditional Chinese medicines for the treatment of stroke. For example, Danshen + Chuanxiong with application numbers 200310103833 and 200710127787 obtained from patent retrieval, ginseng + Chuanxiong with application number 200410065378, Ginseng + Danshen with application numbers 200510021321 and 200410074598 have many injections, and there are basically no effective oral compound preparations with clear and effective components on the market. There is an urgent shortage of clinical medicines for ischemic cerebrovascular diseases, and the curative effects of Chinese and Western medicines are not significant. At present, there is no oral drug that is effective in both the subacute and recovery stages of stroke

Method used

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  • Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof
  • Medicine for treating cardiovascular and cerebrovascular diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Ginseng extract 200g Salvia extract 300g Chuanxiong extract 200g

[0068] Heat and melt polyethylene glycol 6000 and polyoxyethylene 40 stearate, add beta-cyclodextrin and microcrystalline cellulose and stir well, then add ginseng extract, salvia miltiorrhiza extract and Chuanxiong extract in sequence; stir well, 60 Keep warm at -80°C, drop into liquid paraffin, take out the dropping pills after cooling, drain and wipe off the liquid paraffin, and then get the dropping pills.

Embodiment 2

[0070] Ginseng extract 1g Salvia extract 600g Chuanxiong extract 500g

[0071] Heat and melt polyethylene glycol 6000, ginseng extract, salvia miltiorrhiza extract, and Chuanxiong extract are clathrated and solidified with beta-cyclodextrin, and then added to the melted polyethylene glycol 6000; stir well, 60-80°C Keep warm, drop into liquid paraffin, take out the dropping pills after cooling, drain and wipe off the liquid paraffin, and then get the dropping pills.

Embodiment 3

[0073] Ginseng extract 500g Salvia extract 1g Chuanxiong extract 500g

[0074] Heat and melt polyethylene glycol 4000 and polyethylene glycol 6000, add ginseng extract, salvia miltiorrhiza extract, and chuanxiong extract, mix well, keep warm at 60-80°C, drop into simethicone oil, and take out after cooling down , Drain and wipe off the simethicone to obtain the drop pills.

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Abstract

The invention discloses a medicine for treating cardiovascular and cerebrovascular diseases and a preparation method thereof. The medicine is prepared from ginseng extract, salvia extract and ligusticum wallichii extract in a weight ratio, wherein the ginseng extract, salvia extract and ligusticum wallichii extract are commercially available or are obtained by extracting medicinal materials. The medicine can be prepared to obtain pharmaceutically acceptable preparations, optimally drop pills. The medicine has the effects of tonifying qi and promoting blood circulation, is used for treating acute and recovery early stage of cardiovascular and cerebrovascular diseases, especially treating cerebral thrombosis, cerebral ischemia, cerebral infarction and other ischemic cerebrovascular diseases.

Description

[0001] This application is a divisional application of a Chinese invention patent application (name of invention: a drug for treating cardiovascular and cerebrovascular diseases and its preparation method; application date: April 20, 2012; application number: 201210119347.9). technical field [0002] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, especially for treating ischemic encephalopathy, and belongs to the field of traditional Chinese medicine. Background technique [0003] Cerebral ischemia, also known as ischemic stroke or cerebral infarction, belongs to the category of stroke in traditional Chinese medicine. Ischemic brain injury includes primary injury during the ischemic period and secondary injury during the reperfusion period. The initial link in the pathological process is ischemia, and the restoration of blood perfusion in the brain tissue is the basis of its treatment, but the sec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61K9/20A61P9/10A61P25/02A61P7/02A61P9/00A61K31/4965
Inventor 张保献胡杰张永丽
Owner BEIJING INCREASEPHARM CORP LTD
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