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Medicament for treating cardiovascular and cerebrovascular diseases and preparation method of medicament

A technology of medicine and composition, applied in the field of traditional Chinese medicine, can solve the problems of too many injections and ineffective efficacy of traditional Chinese and western medicines

Inactive Publication Date: 2013-10-30
BEIJING INCREASEPHARM CORP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there are only a small number of single preparations and compound preparations composed of two effective parts in traditional Chinese medicines for the treatment of stroke. For example, Danshen + Chuanxiong with application numbers 200310103833 and 200710127787 obtained from patent retrieval, ginseng + Chuanxiong with application number 200410065378, Ginseng + Danshen with application numbers 200510021321 and 200410074598 have many injections, and there are basically no effective oral compound preparations with clear and effective components on the market. There is an urgent shortage of clinical medicines for ischemic cerebrovascular diseases, and the curative effects of Chinese and Western medicines are not significant. At present, there is no oral drug that is effective in both the subacute and recovery stages of stroke

Method used

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  • Medicament for treating cardiovascular and cerebrovascular diseases and preparation method of medicament
  • Medicament for treating cardiovascular and cerebrovascular diseases and preparation method of medicament
  • Medicament for treating cardiovascular and cerebrovascular diseases and preparation method of medicament

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Ginseng extract 200g Salvia extract 300g Chuanxiong extract 200g

[0067] Heat and melt polyethylene glycol 6000 and polyoxyethylene 40 stearate, add beta-cyclodextrin and microcrystalline cellulose and stir well, then add ginseng extract, salvia miltiorrhiza extract and Chuanxiong extract in sequence; stir well, 60 Keep warm at -80°C, drop into liquid paraffin, take out the dropping pills after cooling, drain and wipe off the liquid paraffin, and then get the dropping pills.

Embodiment 2

[0069] Ginseng extract 1g Salvia extract 600g Chuanxiong extract 500g

[0070] Heat and melt polyethylene glycol 6000, ginseng extract, salvia miltiorrhiza extract, and Chuanxiong extract are clathrated and solidified with beta-cyclodextrin, and then added to the melted polyethylene glycol 6000; stir well, 60-80°C Keep warm, drop into liquid paraffin, take out the dropping pills after cooling, drain and wipe off the liquid paraffin, and then get the dropping pills.

Embodiment 3

[0072] Ginseng extract 500g Salvia extract 1g Chuanxiong extract 500g

[0073] Heat and melt polyethylene glycol 4000 and polyethylene glycol 6000, add ginseng extract, salvia miltiorrhiza extract, and chuanxiong extract, mix well, keep warm at 60-80°C, drop into simethicone oil, and take out after cooling down , Drain and wipe off the simethicone to obtain the drop pills.

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Abstract

The invention discloses a medicament for treating cardiovascular and cerebrovascular diseases and a preparation method of the medicament. The medicament is prepared from a ginseng extract, a red-rooted salvia root extract and a hemlock parsley extract according to a certain weight proportion, wherein the ginseng extract, the red-rooted salvia root and the hemlock parsley extract can be obtained by commercial way or extracted from medicinal materials. The medicament can be prepared to form any pharmaceutically acceptable dosage form, preferably drop pills. The medicament has effects of tonifying qi and activating blood circulation, can be used for treating cardiovascular and cerebrovascular diseases, in particular treating in acute and early recovery phase of cerebral thrombosis, cerebral ischemia, cerebral infarction and other ischemic cerebrovascular diseases.

Description

technical field [0001] The invention relates to a medicine for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, especially for treating ischemic encephalopathy, and belongs to the field of traditional Chinese medicine. Background technique [0002] Cerebral ischemia, also known as ischemic stroke or cerebral infarction, belongs to the category of stroke in traditional Chinese medicine. Ischemic brain injury includes primary injury during the ischemic period and secondary injury during the reperfusion period. The initial link in the pathological process is ischemia, and the restoration of blood perfusion in the brain tissue is the basis of its treatment, but the secondary injury after reperfusion Sexual damage is inevitable. Ischemic cerebrovascular disease is extremely harmful. Statistics show that among the 57 countries, 40 countries rank the mortality rate of ischemic cerebrovascular disease in the top three, among which Japan and Ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/537A61P9/10
Inventor 张保献胡杰张永丽
Owner BEIJING INCREASEPHARM CORP LTD
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