Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Lentinan capsule with anti-tumor effect and preparation method thereof

A lentinan and anti-tumor technology, applied in the field of medicine, can solve the problems of inconvenient taking, unstable quality, low bioavailability, etc., and achieve the effects of promoting proliferation, good mechanical properties, and enhancing anti-tumor efficacy.

Inactive Publication Date: 2018-08-24
HUBEI CHUANGLI PHARMA
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its main disadvantages are unstable quality, inconvenient taking, and low bioavailability

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1. Weigh 18g of hydroxypropyl methylcellulose, 0.1g of K-type carrageenan, 0.5g of xanthan gum, 0.01g of potassium chloride, 0.01g of magnesium chloride, 12g of propylene glycol, 0.1g of plasticizer, 0.2g of sorbitol, Potassium dihydrogen phosphate 12g, alginate 25g, purified water 45g.

[0029] 2. Add magnesium chloride, potassium chloride, propylene glycol, sorbitol, potassium dihydrogen phosphate, and plasticizer into water, stir to dissolve, then add K-type carrageenan, xanthan gum, and alginate, heat to dissolve, and then add hydroxypropyl Methyl cellulose, stirred, after layering, cooled to 45°C, heat-preserved and defoamed to obtain capsule glue, set aside;

[0030] 3. Dip the mold needle into the capsule glue, turn it over 2-5 times, and bake a single-section capsule;

[0031] 4. The finished capsule is obtained after the single section of the body cap is cut and fitted.

[0032] 5. Weigh 25g of lentinan and 15g of Ganoderma lucidum powder, crush the lentinan ...

Embodiment 2

[0037] 1. Weigh 24g of hydroxypropyl methylcellulose, 12g of K-type carrageenan, 20g of xanthan gum, 17g of potassium chloride, 17g of magnesium chloride, 18g of propylene glycol, 0.5g of plasticizer, 0.5g of sorbitol, and potassium dihydrogen phosphate 15g, 38g of alginate, 64g of purified water.

[0038] 2. Add magnesium chloride, potassium chloride, propylene glycol, sorbitol, potassium dihydrogen phosphate, and plasticizer into water, stir to dissolve, then add K-type carrageenan, xanthan gum, and alginate, heat to dissolve, and then add hydroxypropyl Methyl cellulose, stirred, after layering, cooled to 45°C, heat-preserved and defoamed to obtain capsule glue, set aside;

[0039] 3. Dip the mold needle into the capsule glue, turn it over 2-5 times, and bake a single-section capsule;

[0040] 4. The finished capsule is obtained after the single section of the body cap is cut and fitted.

[0041] 5. Weigh 35g of lentinan and 25g of Ganoderma lucidum powder, crush the lenti...

Embodiment 3

[0046] 1. Weigh 21g of hydroxypropyl methylcellulose, 5g of K-type carrageenan, 10g of xanthan gum, 12g of potassium chloride, 10g of magnesium chloride, 15g of propylene glycol, 0.3g of plasticizer, 0.3g of sorbitol, and potassium dihydrogen phosphate 13g, 30g of alginate, 55g of purified water.

[0047] 2. Add magnesium chloride, potassium chloride, propylene glycol, sorbitol, potassium dihydrogen phosphate, and plasticizer into water, stir to dissolve, then add K-type carrageenan, xanthan gum, and alginate, heat to dissolve, and then add hydroxypropyl Methyl cellulose, stirred, after layering, cooled to 45°C, heat-preserved and defoamed to obtain capsule glue, set aside;

[0048] 3. Dip the mold needle into the capsule glue, turn it over 2-5 times, and bake a single-section capsule;

[0049]4. The finished capsule is obtained after the single section of the body cap is cut and fitted.

[0050] 5. Weigh 30g of lentinan and 20g of Ganoderma lucidum powder, crush the lentina...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Finenessaaaaaaaaaa
Finenessaaaaaaaaaa
Finenessaaaaaaaaaa
Login to View More

Abstract

The invention relates to the technical field of medicines, in particular to a lentinan capsule with an anti-tumor effect and a preparation method thereof. According to the lentinan capsule with the anti-tumor effect, lucid ganoderma bioactive substances capable of improving body immunity and an anti-aging effect and lentinan with the anti-tumor effect are also used for promoting proliferation anddifferentiation of organism stem cells, improving body immunity and the anti-aging effect and further enhancing the anti-tumor curative effect of the capsule. A capsule shell adopts pure plant raw materials, a capsule shell prepared by compounding K-type carrageenan and xanthan gum is also used, and the capsule is good in mechanical property, resistant to high temperature and antibacterial and solves the technical problems that a large quantity of chemical components exist in animal gelatin and cause severe pollution to air and the water environment.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a lentinan capsule with antitumor effect and a preparation method thereof. Background technique [0002] Lentinus edodes belongs to the Basidiomycetes umbrella fungus, and is a very popular edible fungus in the world. The main ingredient in shiitake mushrooms is lentinan, which mostly exists in the form of mixed polysaccharides, including 4 kinds of heteropolysaccharides and 2 kinds of glucans, among which glucans are biologically active, and their structure is β-(1→3) The glucopyranoside bond is the main chain, and the β-(1→6) glucopyranoside bond is the branch. [0003] Modern research shows that lentinan has the functions of regulating immunity, anti-tumor, lowering blood sugar, anti-virus and anti-oxidation. Lentinan has immunoregulatory effects on the body, mainly because it is a typical T cell activator, which can promote delayed hypersensitivity in the body, increase th...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/074A61K31/715A61K9/48A61K47/36A61P35/00
CPCA61K9/4816A61K31/715A61K36/074A61K47/36A61P35/00A61K2300/00
Inventor 张仁刘刘少敏谢华郭传功
Owner HUBEI CHUANGLI PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com