Composition capable of lowering blood glucose as well as preparation and application of composition

A technology of composition and mixed powder, applied in application, drug combination, food science and other directions, can solve the problems of aging of pancreatic islet function, large side effects, slow onset process, etc., and achieve the effect of improving water consumption

Inactive Publication Date: 2018-08-14
上海紫石生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Diabetes is a chronic endocrine and metabolic disease that is caused by a variety of reasons and causes multi-system and multifunctional damage caused by sugar and fat metabolism disorders. Foreign researchers have achieved certain results in long-term research. And health care products come out continuously, but although the effect of western medicine is significant, its side effects are also relatively large. Long-term use will accelerate the aging of islet function, damage other organs of the body, especially the liver, kidney and other organs, and induce various complications
The ideal treatment goal of type II diabetes is not only to reduce blood sugar to within the policy range, but also to bring what is in the body to a normal level, because once the mechanism of chronic complications of diabetes starts, the onset process is slow, but simple blood sugar control does not prevent the progression of the disease
Western medicine oral hypoglycemic drugs and insulin injections can effectively control blood sugar, but there are no effective measures for the prevention and quality of chronic complications of diabetes

Method used

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  • Composition capable of lowering blood glucose as well as preparation and application of composition
  • Composition capable of lowering blood glucose as well as preparation and application of composition
  • Composition capable of lowering blood glucose as well as preparation and application of composition

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preparation example Construction

[0056] The composition of the present invention is particularly preferably prepared in the form of a tablet to facilitate eating or taking, so the present invention also provides food, medicine or health care products (such as drug tablets, such as hypoglycemic Chinese medicine tablets) comprising tablet forms of the composition of the present invention The preparation method of agent), it comprises the following steps:

[0057] (1) Sieve the auxiliary material (if necessary) and American ginseng extract, balsam pear extract, mulberry leaf extract, and chromium-enriched yeast, and weigh them in parts by weight as described herein for later use;

[0058] (2) Mix the excipients and components weighed in the previous step to get the total mixed powder;

[0059] (3) making the soft material by said total mixed powder;

[0060] (4) making the soft material made into wet granules;

[0061] (5) drying the wet granules to obtain dry granules;

[0062] (6) Add appropriate auxiliary ...

Embodiment 1

[0102] A hypoglycemic tablet, comprising the following raw materials in parts by weight: 50 parts of mulberry leaf extract, 100 parts of bitter melon extract, 25 parts of American ginseng extract, and 5 parts of chromium-rich yeast; it also contains the following auxiliary materials in parts by weight: microcrystalline cellulose 150 parts, 10 parts of sodium carboxymethyl starch, 5 parts of magnesium stearate, 15 parts of coating powder. The coating powder is composed of hydroxypropyl methylcellulose and polyethylene glycol 6000, and the ratio of the two is 1:1.

[0103] The preparation method of this hypoglycemic tablet, concrete steps are as follows:

[0104] (1) Pass the sodium carboxymethyl starch, American ginseng extract, balsam pear extract, mulberry leaf extract, microcrystalline cellulose, magnesium stearate and chromium-enriched yeast through 80 mesh sieves respectively, press the parts by weight weighing spare;

[0105] (2) The sodium carboxymethyl starch, America...

Embodiment 2

[0113] A hypoglycemic tablet, comprising the following raw materials in parts by weight: 100 parts of mulberry leaf extract, 200 parts of bitter melon extract, 75 parts of American ginseng extract, and 10 parts of chromium-rich yeast; it also contains the following auxiliary materials in parts by weight: microcrystalline cellulose 160 parts, 10 parts of sodium carboxymethyl starch, 7 parts of magnesium stearate, 16 parts of coating powder. The coating powder is composed of hydroxypropyl methylcellulose and polyethylene glycol 6000, and the ratio of the two is 1:1.

[0114] The preparation method of this hypoglycemic tablet is the same as in Example 1.

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Abstract

The invention discloses a composition capable of lowering blood glucose as well as preparation and application of the composition. The composition capable of lowering the blood glucose is prepared from the following components in parts by weight: 50 to 350 parts of folium mori extract, 100 to 500 parts of bitter gourd extract, 75 to 250 parts of American ginseng root extract and 5 to 50 parts of chromium-enriched yeast. The invention further discloses food, medicine or health-care product containing the composition and a related preparation method. According to the composition capable of lowering the blood glucose or tablets capable of lowering the blood glucose, folium mori, bitter gourds, American ginseng root and the chromium-enriched yeast are matched according to a prescription and the use amount of each component is limited; the composition has a remarkable improvement effect on main clinical symptoms of diabetes mellitus.

Description

technical field [0001] The invention relates to the field of hypoglycemic products, in particular to a hypoglycemic composition and its preparation and application. Background technique [0002] With the continuous development of social economy, the increase of work pressure, genetic factors, unhealthy lifestyle and improper diet structure and other factors, the incidence of diabetes is increasing year by year, and it has gradually become a disease following cardiovascular and cerebrovascular diseases and malignant diseases. After tumor, it is the third largest "health killer" affecting human death. [0003] In recent decades, the number of people with diabetes worldwide has increased at an alarming rate, especially type 2 diabetes. In 1979, the incidence rate of type II diabetes in China was 1.00%, which increased rapidly to 3.21% in 1996, and increased to 4-5% in 2002. At present, there are about 22.6 million diabetic patients in China. At the current growth rate, it is ...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61K9/20A61K9/36A23L33/00A61P3/10A61K33/24
CPCA23L33/00A23V2002/00A61K9/2059A61K9/2866A61K33/24A61K36/064A61K36/258A61K36/42A61K36/605A61P3/10A61K2300/00A23V2200/328A23V2250/21A23V2250/2124
Inventor 廖靖军
Owner 上海紫石生物科技有限公司
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