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Digestion-promoting traditional Chinese medicine or food as well as preparation method and application thereof

A technology to promote digestion and food, applied in the application, digestive system, food ingredients and other directions, can solve the problems of inability to completely cure, easy to relapse, etc., and achieve the effect of promoting gastric emptying

Inactive Publication Date: 2018-06-15
KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When synthetic digestive drugs are used clinically, they can only achieve the purpose of relieving symptoms, but cannot completely cure them, and are prone to relapse

Method used

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  • Digestion-promoting traditional Chinese medicine or food as well as preparation method and application thereof
  • Digestion-promoting traditional Chinese medicine or food as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Traditional Chinese medicine or food for promoting digestion, made of the following raw materials by weight: Cynanchumauriculatum royle ex weight, hawthorn, malt, divine comedy, Poria cocos, crushed into coarse powder, proportioned by weight, plus 8 times the amount 70% ethanol solution, heated and refluxed for 3 times, 2 hours each time, filtered, combined filtrate, concentrated under reduced pressure below 60°C to a relative density of 1.1-1.15 (60°C), then added water 3 times the weight of the medicinal material, and stood still for 24 hours, filter, take the supernatant and concentrate under reduced pressure below 60°C to a thick paste with a relative density of 1.2-1.3 (60°C), and mix the thick paste with the pharmaceutically acceptable excipients in a weight ratio of 1:15 , granulating, tableting, bagging and sealing.

Embodiment 2

[0021] The traditional Chinese medicine or food for promoting digestion is prepared from the following raw materials in parts by weight: 1200g of Cynanchumauriculatum royle ex weight, 300g of hawthorn, 200g of malt, 200g of Divine Comedy, and 100g of Poria cocos. Its preparation method is as follows: pulverize Erye Niupixiao, hawthorn, malt, Shenqu and Poria cocos into coarse powder, mix according to weight ratio, add 8 times the amount of 70% ethanol solution, heat and reflux extraction for 3 times, each time for 2 hours, and filter , Combine the filtrates, concentrate under reduced pressure below 60°C to a relative density of 1.1-1.15 (60°C), then add 6kg of water, stand still for 24 hours, filter, take the supernatant and concentrate under reduced pressure below 60°C to a relative density of 1.2-1.3 (60°C) thick paste, 297.2g of thick paste was obtained, the thick paste and pharmaceutically acceptable excipients were mixed uniformly in a weight ratio of 1:15, granulated, com...

Embodiment 3

[0023] The impact of the composition of the present invention on the improvement of gastrointestinal motility in male ICR mice:

[0024] 1 drug

[0025] (1) Test substance

[0026] The digestive extract of embodiment 2 gained.

[0027] (2) Control drug

[0028] Mosapride citrate tablet, approved by the Chinese Medicine: H20031110, 5 mg / tablet, the usual dose for adults is 1 tablet each time, 3 times a day; produced by Chengdu Kanghong Pharmaceutical Group Co., Ltd.

[0029] (3) Dose setting and preparation method

[0030] Mosapride citrate tablet, clinical dosage is 15mg / day / person, and test dose is set as 5mg / kg, is equivalent to 20 times of clinical dosage, is mixed with the suspension of 0.125mg / mL concentration with pure water.

[0031] Three dosage groups are set up for the digestion-promoting extract, 400, 200, and 100 mg / kg respectively, and they are prepared into suspensions with concentrations of 20, 10, and 5 mg / mL with pure water.

[0032] In order to ensure th...

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Abstract

The invention discloses a digestion-promoting traditional Chinese medicine compound formula medicine or food as well as a preparation method and application thereof. A traditional Chinese medicine compound formula is mainly prepared from herba cynanchi auriculati royle, fructus crataegi, malt, medicated leaven, poria cocos and the like; scientific processing and extraction are carried out according to physiochemical properties of raw materials of the formula; the raw materials and a pharmaceutically acceptable excipient are prepared into an oral solid preparation or a liquid preparation according to a conventional method. The invention also provides application of the traditional Chinese medicine compound formula to preparation of medicines or foods for treating abdomen swelling, appetiteloss and functional dyspepsia symptoms; the raw materials provided by the invention are raw materials both used as medicines and foods and have no toxic and side effects.

Description

Technical field: [0001] The invention belongs to the field of medicine or health food, and in particular relates to a preparation method of a traditional Chinese medicine or food for promoting digestion and its application in preparing medicine or food for treating abdominal distension and pain, not wanting to eat, and functional dyspepsia. Background technique: [0002] Functional dyspepsia is a disease caused by disturbance of gastric motility. The common symptoms are epigastric discomfort or pain, bloating, heartburn, belching, etc. Traditional Chinese medicine believes that the spleen governs movement and transformation, and opens to the mouth. The spleen is closely related to appetite and taste. If the spleen is healthy, the appetite will be strong. On the contrary, if the spleen and stomach are weak and the spleen is not healthy, the appetite will be poor, and the mouth will be tasteless. The existence and size of the spleen reflect the function and healthy nature of t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8998A61P1/14A61P1/00A23L33/105A23L31/00
CPCA23L31/00A23L33/105A23V2002/00A61K36/00A61K36/076A61K36/27A61K36/734A61K36/8998A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00A23V2200/30A23V2200/32A23V2250/21A23V2250/208A23V2300/14
Inventor 沈勇李晓波
Owner KUNMING INST OF BOTANY - CHINESE ACAD OF SCI
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