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Alzheimer disease resistance composition containing active extract of semen malaniae oleifen and application thereof

A technology for Alzheimer's disease and garlic cloves, which is applied in the directions of medical preparations, drug combinations, and applications containing active ingredients, can solve problems such as no anti-Alzheimer's disease compositions, and achieves improved efficacy. The effect of ingredient content

Inactive Publication Date: 2017-12-08
杨宇明
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there is no report on the anti-Alzheimer's disease composition and its application using the effective extract of garlic fruit as the active ingredient in the prior art

Method used

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  • Alzheimer disease resistance composition containing active extract of semen malaniae oleifen and application thereof
  • Alzheimer disease resistance composition containing active extract of semen malaniae oleifen and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] First prepare the garlic fruit active ingredient:

[0033] Preparation of garlic seed oil:

[0034] Collect 10.0kg of fresh garlic fruit, remove the green skin, dry in the shade until the water content does not exceed 13-15%, remove the seed shell, and crush the seed kernel to obtain particles with a diameter of about 1-2cm. The method is to heat with water steam for 20-30 minutes, turn the granules every 5 minutes, steam until cooked, take it out and let it cool, soak it in petroleum ether (boiling range 60-90°C), and the ratio of liquid to material is 5-10:1 (V: V / g:L), after soaking for 30-40min, use ultrasonic-assisted extraction, extraction temperature 25-40°C, ultrasonic power 400-600W, each extraction time is 30-60min, extract 3-5 times, combine the extracts, Concentrate under reduced pressure at a concentration temperature of 30-50°C. After the petroleum ether is completely volatilized, 670.0 g of garlic seed oil is obtained.

[0035] Preparation of phytonervo...

Embodiment 2

[0042] Firstly, according to the method of Example 1, nervonic acid, garlic polyphenols, and garlic water-soluble protein were respectively prepared, and each component was selected according to the following components by mass: nervonic acid 10-50g, garlic polyphenols 10-100g, Garlic fruit water-soluble protein 10-100g, dextrin 100-1000g, appropriate amount of 50% ethanol. The above-mentioned raw and auxiliary materials are prepared according to the conventional process for preparing granules, that is, the raw and auxiliary materials are inspected and weighed—soft materials—granulated—dried—granulated—finished product packaging—sterilized. Granule specification: 20g / bag.

Embodiment 3

[0044] Firstly, according to the method of Example 1, nervonic acid, garlic polyphenols, and garlic water-soluble protein were respectively prepared, and each component was selected according to the following components by mass: nervonic acid 10-50g, garlic polyphenols 10-100g, Garlic fruit water-soluble protein 10-100g, mixed, added to solid and liquid foods such as jam, milk, honey, etc. with a ratio of 1-9:1, to exert its health care function.

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Abstract

The invention relates to an alzheimer disease resistance composition containing an active extract of semen malaniae oleifen. The alzheimer disease resistance composition is prepared from the following components in parts by mass: 0 to 5 parts of nervonic acid, 0 to 10 parts of semen malaniae oleifen polyphenol, 0 to 10 parts of semen malaniae oleifen water-soluble protein and 1 to 80 parts of accessories, wherein the parts of the first to the third components cannot be equal to 0 simultaneously. Semen malaniae oleifen is used as a raw material; the plant nervonic acid, the semen malaniae oleifen polyphenol and the semen malaniae oleifen water-soluble protein are extracted from kernels of the malania oleifen by adopting a plant chemical separation purification means and form the alzheimer disease resistance medicinal composition. The alzheimer disease resistance composition is respectively prepared into health care foods, middle-aged and old-aged nutritious foods and brain-strengthening replenishers for application.

Description

technical field [0001] The present invention belongs to the field of pharmacy, in particular, relates to the application field of extraction of natural products, more specifically, relates to an anti-Alzheimer's disease composition and its application. Background technique [0002] With the development of my country's economy and the implementation of population policy, the age structure of my country's population has undergone great changes. China's life expectancy rose from 68.4 years in 1990 to 73.8 years in 2008, and the proportion of the elderly population in the total population is increasing. According to the data provided by the Organization for Economic Cooperation and Development, relative to China's total population, it is estimated that The proportion of the population over the age of 65 will rise from 7.8% in 2005 to 16.3% in 2030. [0003] According to statistics, there are now 24 million dementia patients in the world. In my country, the number of patients w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K31/201A61K38/01A61P25/28A23L33/105A23L33/185
CPCA23L33/105A23L33/185A23V2002/00A61K31/201A61K36/185A61K38/011A61K2236/15A61K2236/333A61K2236/35A61K2236/39A61K2236/53A61K2300/00A23V2200/30A23V2250/212A23V2250/2132A23V2250/548
Inventor 杨宇明王娟施蕊刘祥义
Owner 杨宇明
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