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Anastomotic/occlusion reinforcing and repairing composite member as well as preparation and application method thereof

An assembly and closing technology, applied in the field of medical devices, to achieve the effect of ensuring safety and stability, low pathogenicity, and no cell residues

Active Publication Date: 2017-05-31
BEIJING BIOSIS HEALING BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these synthetic materials cannot help the wound surface (nail hole and cut surface) to heal

Method used

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  • Anastomotic/occlusion reinforcing and repairing composite member as well as preparation and application method thereof
  • Anastomotic/occlusion reinforcing and repairing composite member as well as preparation and application method thereof
  • Anastomotic/occlusion reinforcing and repairing composite member as well as preparation and application method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Preparation of reinforcement repair sheet

[0045] It should be noted that the reinforcement repair sheet is one of the commonly used products of the reinforcement repair part of the present invention.

[0046] The reinforcement repair sheet can be prepared as follows:

[0047] (a) Raw material selection and initial treatment: Choose the Chinese inbred Wuzhishan miniature pig as the animal source, and determine the animal species using the method specified in the patent ZL200510008994.2, and clean the small intestine tissue of the freshly slaughtered Chinese inbred Wuzhishan miniature pig Clean, separate the small intestinal submucosal tissue, divide the small intestinal submucosal tissue into specified size, remove the lymphatic tissue, rinse with tap water for 1 to 3 times, and then rinse with purified water until the surface is free of stains, and the washed small intestinal submucosal tissue is static Set, sieve filter.

[0048] (b) Risk treatment: Use peracetic acid-ethan...

Embodiment 2

[0057] Effect verification experiment of the reinforcement repair sheet of the present invention

[0058] Preferably, the degradation time in the body is 1 to 3 months. The mechanical properties of the reinforcement repair sheet include rupture strength, suture retention and / or tensile strength. figure 1 Is the HE stained section of the reinforcement repair piece; from figure 1 It can be seen that after the HE staining, the sample in Example 1 is observed through an optical microscope, and it can be seen that the preparation method provided in the present invention has complete and continuous retention of the extracellular matrix without cell residue.

[0059] Observing the sample through a scanning electron microscope, it can be seen that the extracellular matrix sheet of the submucosa tissue of the small intestine is obtained after processing. The collagen fiber is intact, undamaged, and unbroken. It is an interlaced porous network structure. It proves that this structure can pro...

Embodiment 3

[0085] The first kind of woven mesh structure is divided into a first free section 1311, a plurality of first semi-open sections 1312, a pulling section 1313, a holding section 1314, a locking section 1315, and a first release section 1311, which are connected to each other, from the start end to the end. Section 1316, the number of the first semi-open sections 1312 may be the same as the number of the hole pairs 111, the rope sleeve enclosed by each first semi-open section 1312 communicates with the two line holes of the hole pair 111 as a whole, the first half The open end of the open section 1312 is located at the same end of the reinforced repair part 11, and the locking section 1315 passes through the rope sheath enclosed by the first semi-open section 1312; from the knitting start end to the knitting end, the first half-open section 1312 The end of the opening close to the braiding start end is connected to the first free section 1311, the opening of the last first semi-op...

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Abstract

The invention relates to the technical field of medical equipment and discloses an anastomotic / occlusion reinforcing and repairing composite member which comprises a reinforcing and repairing part, a protection part and a connection line, wherein the two ends of the reinforcing and repairing part are detachably connected by the connection line; and the protection part penetrates into a space enclosed by the two ends of the reinforcing and repairing part. The invention also provides a preparation and application method of the anastomotic / occlusion reinforcing and repairing composite member. The anastomotic / occlusion reinforcing and repairing composite member disclosed by the invention can provide enough strength to the to-be-treated tissue to prevent suture tearing; with low or nearly no immunogenicity, the composite member realizes relatively low pathogenicity and high biocompatibility, while a large number of beneficial components promoting tissue repairing are maintained.

Description

Technical field [0001] The invention relates to the technical field of medical devices, in particular to a kiss / closure reinforcement repair assembly and a preparation and use method thereof. Background technique [0002] Surgical reinforcement devices can quickly cut and seal the tissues and organs of the patient at the same time. Compared with the first scalpel / cutting of conventional surgery, the risk of such surgical procedures is greatly reduced. And shorten the operation time, so it has a very wide range of applications in surgery. The general surgical reinforcement device has a jaw structure, usually including two separate arms, the inner face is the working surface. The first arm is preferably a staple cartridge arm with a staple cartridge surface including two or more staple lines, and the second arm is preferably a staple anvil arm with a staple anvil surface. The surgical reinforcement device can be with or without a cutting device with a cutting effect. [0003] In a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B17/072A61B17/115A61L31/14A61L31/00
CPCA61B17/07207A61B17/1155A61L31/005A61L31/14A61L31/146A61L31/148A61B2017/00831A61B2017/00526A61B2017/00004A61B17/07292A61B17/115A61B17/12168A61B17/0466A61B17/06166
Inventor 赵博李学军王洪权赵延瑞费福磊张晋辉孙丹丹
Owner BEIJING BIOSIS HEALING BIOLOGICAL TECH
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