Vaginal gel and preparation method thereof

Abstract

The invention relates to the technical field of preparation of colpitis medicines, and especially relates to a vaginal gel and a preparation method thereof in order to solve the technical problem of unsatisfactory bacteriostasis, lubrication and moisture retention effects of existing vaginal gel products. The vaginal gel mainly comprises sodium hyaluronate, vitamin E succinate modified hyaluronic acid, EGF (epidermal growth factors), vitamins C, calcium chloride, pentanediol, glycerin, Rhodicare and a buffer system adopting disodium hydrogen phosphate-citric acid as gel. The vaginal gel has anti-inflammatory activity, improves the wetness of vaginas, is used for treating vaginal inflammatory diseases and alleviating vaginal dryness or used as a human body lubricant, has a vaginal mucosa squamous cell layer restoration promoting effect, can improve vaginal mucosa layer thinning and restore small injuries in vaginas to recover the elasticity and the softness of the vaginal mucosa, and is suitable for colpitis and vagina dryness people.

Description

technical field [0001] The invention relates to the technical field of vaginitis medicine preparation, in particular to a vaginal gel and a preparation method thereof. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women, including bacterial vaginosis, fungal vaginitis and trichomonas vaginitis. The clinical symptoms of vaginitis are mainly manifested as increased vaginal discharge with peculiar smell, genital itching, and causing cervical and uterine infection and pelvic inflammatory disease. The main population of vaginal dryness or atrophic vaginitis is postmenopausal women. According to survey statistics, about half of postmenopausal women have vaginal dryness. The vaginal mucosa is composed of glycogen-rich nonkeratinized stratified squamous epithelium and a fibrous basement membrane. During the reproductive period, the stratified squamous epithelium is rich in glycogen, and the vaginal mucosa is moist and elastic. After menop...

AI Technical Summary

Problems solved by technology

[0003] Currently, the treatment products for vaginitis or vaginal dryness are divided into three categories: 1. Western medicines, such as metronidazole, chlorhexidine, miconazole and ketoconazole, etc., are bactericidal and antibacterial. Western medicines have quick effects but are prone to drug resistance and There are side effects; 2. Traditional Chinese medicine, such as cnidium fruit, flavescens, Phellodendron cortex, alum, licorice, borneol and Kochia scoparia, etc., have the functions of clearing away heat and detoxification, killing insects and relieving itching, and the simple use of traditional Chinese medicine is slow to take effect and cannot relieve symptoms in time; 3. Devices There are two categories, one is treatment with ozone or red light and other physiotherapy equipment, which requires patients to go to the hospital for treatment regularly or purchase treatment equipment by themselves, the cost is high; the other is chitosan, silver ions and other vaginal antibacterial gels, Using biological antibacterial raw materials, instant, convenient, fast and economical treatment of vaginitis, the use and curative effect of the gel have been widely recognized

However, the antibacterial, lubricating and moisturizing effects of current vaginal gel products are not ideal enough