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Plant bacteriostatic composition and application thereof in daily necessities

A plant antibacterial and composition technology, applied in the field of daily necessities, can solve problems such as mutagenesis, skin irritation, teratogenicity, etc., and achieve good anti-infection and good antibacterial effects.

Inactive Publication Date: 2017-02-22
GUANGDONG IND TECHN COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most antibacterial agents are prepared by chemical synthesis. These chemically synthesized antibacterial agents are cheap and have antibacterial effects to a certain extent. However, long-term use can easily cause skin irritation, allergies, and accelerated aging. and other phenomena, even lead to potential carcinogenic, teratogenic and mutagenic

Method used

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  • Plant bacteriostatic composition and application thereof in daily necessities
  • Plant bacteriostatic composition and application thereof in daily necessities
  • Plant bacteriostatic composition and application thereof in daily necessities

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-4

[0014] Embodiment 1-4 A kind of plant antibacterial composition

[0015] Table 1 is the consumption of each component in a kind of plant antibacterial composition of embodiment 1-4.

[0016] Table 1

[0017]

[0018] The preparation method of a kind of plant antibacterial composition described in embodiment 1-4 is as follows: take each component, pulverize, sieve with 60 mesh sieves respectively, mix, add volume fraction by liquid material mass ratio 15:1 is 50% ethanol, after soaking for 2 hours, use a high-pressure homogeneous extractor to extract at room temperature under the extraction pressure of 40MPa. After the extract is centrifuged, it is concentrated with a membrane. 40%, 70%, 95% ethanol was eluted multiple times, the eluate was collected, and the membrane was concentrated until the mass ratio of the extract to the plant component was 1:1, then dissolved in butanediol and filtered to obtain the plant inhibitor bacteria composition.

experiment example 1

[0028] Experimental example 1 antibacterial experiment

[0029] The tested bacteria were bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa, Aspergillus niger and Candida albicans. Resurrect the above bacterial species and culture them under the following conditions respectively. Bacteria use lecithin Tween 80-nutrient agar medium and culture at 30-37°C for 36-48 hours; Aspergillus niger use Bengal red medium and culture at 20-25°C for 120 hours; For Candida albicans, use potato dextrose agar medium and culture at 20-25°C for 24-48 hours. The bacterial concentration was diluted to 1.0×10 9 CFU / mL, the concentration of Candida albicans was diluted to 1.0×10 9 CFU / mL, the Aspergillus niger concentration was diluted to 1.0×10 7 CFU / mL. Pipette 0.1 mL of the above-mentioned bacterial dilution on the plates containing the corresponding solid medium, spread evenly with a spreading rod, put 4 Oxford cups equidistantly in each plate, and add 0.1 mL...

experiment example 2

[0033] Experimental example 2 irritation test

[0034] The plant antibacterial composition of Example 1 and the traditional bacteriostatic agent of Comparative Example 6 were subjected to the chicken chorioallantoic membrane blood vessel test, and the reaction irritation of the blood vessels was observed, which reflected the irritation of the sample to the skin. The experiment was carried out by utilizing the characteristics of complete, obvious and transparent blood vessels of CAM (ie, fertilized mid-stage chorioallantoic membrane of hatched 10-14-day embryonic embryo). The plant antibacterial composition and the traditional bacteriostatic agent of Comparative Example 6 are contacted with 2 CAMs respectively, act for a period of time, observe the degree of CAM vascular damage, and score the irritation, the more serious the vascular damage, the greater the score, the greater the irritation. bigger. Judgment criteria are shown in Table 3, and irritation results are shown in Ta...

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Abstract

The invention discloses a plant bacteriostatic composition and application thereof in daily necessities. The plant bacteriostatic composition is prepared from the following plants: radix sophorae flavescentis, radix et rhizoma rhei, rhizoma belamcandae, radix scutellariae and rhizoma polygoni cuspidati. The plant bacteriostatic composition is prepared by carrying out high pressure homogeneous extraction, centrifugal separation and membrane concentration, and then carrying out macroreticular resin absorption separation and membrane concentration. The plant bacteriostatic composition does not contain chemosynthetic substances, thus being non-toxic, free from side effects, safe and reliable, and being directly applied to the skin; the plant bacteriostatic composition effectively removes and inhibits microorganisms such as bacteria, fungi and viruses on the skin of a human body, and has the functions of being capable of effectively preventing the human skin from being infected by the microorganisms, resisting allergy, treating eczema, and the like. The plant bacteriostatic composition can be used as a bacteriostatic function material for the daily necessities with a bacteriostasis function, and can be added into the daily necessities such as shampoo, bath foam, liquid soap, cosmetics and soaps so as to be prepared into anti-dandruff shampoo, antibacterial bath foam, antibacterial liquid soap, acne-removing cosmetics and antibacterial soaps.

Description

technical field [0001] The invention relates to a plant antibacterial composition. The extract of the composition has antibacterial function and can be applied to prepare daily necessities, belonging to the technical field of daily necessities. Background technique [0002] In people's daily life, especially in spring and summer, the ambient humidity increases, the temperature rises, and various bacteria, fungi, and viruses become active. Bacteria and viruses are always spread with the contact between items and other channels. to human skin. Bacteria and fungi on the skin have brought great safety hazards to people's lives and caused some skin diseases, such as dandruff, eczema, psoriasis, acne, and antibiotic-resistant infectious diseases. [0003] With the improvement of living standards, people's consumption of daily necessities is increasing day by day, and the daily necessities with antibacterial effect are also increasing day by day. At present, most antibacterial ag...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q17/00A61P31/02
CPCA61K8/97A61Q17/005
Inventor 龚盛昭李仕梅
Owner GUANGDONG IND TECHN COLLEGE
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