Method for preparing individualized porous implant through selective laser formation and electrolytic reduction

Abstract

The invention provides a method for preparing an individualized porous implant through selective laser formation and electrolytic reduction. The method comprises the following steps: according to human body characteristics of a part needing an implant, carrying out individualized porous implant design with a microstructure through utilizing a medical image data reverse model; preparing a metal oxide ceramic porous implant with a microstructure through utilizing a selective laser melting / sintering additive manufacturing method; carrying out the electrolytic reduction on molten chloride melt to obtain a primary porous metal implant with a nanostructure, and sintering at a high temperature; depositing the same metal coating on the surface of the primary porous metal implant by utilizing a chemical vapor deposition method. By adopting the method provided by the invention, the disadvantages of a traditional porous implant preparation method that the microstructure cannot be controlled and the difficulty of direct laser additive manufacturing is great are overcome; structure nano-crystallization can be realized, a new way for preparing the porous implant is hopefully explored; the method has an important meanning on promotion of clinical application of the porous implant.

Description

technical field [0001] The invention relates to a method for preparing a personalized porous implant by selective laser forming and electrolytic reduction. The method belongs to the field of biological additive manufacturing (3D printing) and can be applied to the field of biomedicine. Background technique [0002] Additive manufacturing has important applications in the medical field, especially for the manufacture of personalized implants, which has unparalleled advantages and a potential market of tens of billions in the future. At present, implants manufactured by direct metal forming of various metal materials such as stainless steel, titanium alloy and cobalt-based alloy have been widely used in heart valve stents, vascular stents, digestive tract stents, bone repair and replacement stents and other stents clinically, and achieved better therapeutic effect. However, the complex environment in the human body will cause material corrosion and release of toxic elements, ...

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the shortcomings of the difficulty of direct laser additive manufacturing of porous implants, the uncontrollable microstructure and the inability to form nanostructures, the purpose of the present invention is to provide a metal oxide ceramic with a micro-nano structure prepared by selective laser forming and electrolytic reduction. A personalized porous implant method, which combines the additive manufacturing method, electrolytic reduction method and chemical vapor deposition method, can realize the controllable formation of microstructure, and the formation of nanostructure is conducive to cell activities, which is expected to open up the preparation of porous scaffolds A new way to improve the biocompatibility of porous implants is of great significance for promoting the clinical application of porous implants