Preparation method of biological veterinary drug for preventing and treating hydropericardium hepatitis syndrome in chickens

Abstract

The invention relates to the technical field of a biological veterinary drug, in particular to a preparation method of a biological veterinary drug for preventing and treating hydropericardium hepatitis syndrome in chickens. The preparation method comprises steps of preparing an antigen, determining an antigen EID50, preparing an inactivated vaccine, immunizing laying chickens, collecting eggs from hype-immunized chickens and extracting an anti-hydropericardium hepatitis syndrome egg yolk antibody. According to the egg yolk antibody biological veterinary drug for treating the hydropericardium hepatitis syndrome in chickens provided by the invention, chicken embryo proliferating viruses are inoculated to liver tissue homogenate of chickens affected by the hydropericardium hepatitis syndrome in chickens, the laying chickens are immunized by the prepared inactivated vaccine, protein is extracted from egg yolks and the protein is used for preventing and treating the hydropericardium hepatitis syndrome in chickens, so as to solve the problem that a targeted veterinary drug for treating the hydropericardium hepatitis syndrome in chickens is in lack at present and the problems that a current popular treatment scheme is high in cost and poor in effect.

Description

technical field [0001] The invention relates to the technical field of biological veterinary drugs, in particular to a preparation method of biological veterinary drugs for preventing and treating chicken pericardial effusion-hepatitis syndrome. Background technique [0002] Hydropericardium hepatitis syndrome (Hydropericardium hepatitis syndrome, chicken pericardium-hepatitis syndrome), the typical symptom is a sudden onset of broiler chickens aged 3-6 weeks, accompanied by typical symptoms of pericardial effusion and hepatitis, which can also be seen in meat species Chickens and layers. According to research, Fowladenovirus serotype 4 (FAV4) is one of the pathogens causing this disease. It was found that there were basophilic intranuclear inclusion bodies in the liver cells of sick chickens, and after the liver homogenate was aseptically processed, The same condition can be reproduced. The icosahedral virus was observed from the diseased chicken liver under the electron ...

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the deficiencies in the existing biological veterinary drug technology for preventing and treating chicken pericardial effusion-hepatitis syndrome, the invention provides a preparation method of biological veterinary medicine for preventing and treating chicken pericardial effusion-hepatitis syndrome, solving the problem that there is no suitable treatment for chicken pericardium at present The problem of high cost and poor effect of targeted veterinary drugs for effusion-hepatitis syndrome

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