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Pharmaceutical composition for local anaesthesia

A technology of local anesthesia and composition, applied in the field of medicine, can solve the problems of complicated operation, unsuitable control of dosage, small toxic and side effects, etc., and achieve the effects of reasonable compatibility, rapid onset of effect, and rigorous formulation.

Inactive Publication Date: 2016-06-08
唐国萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the anesthesia operation performed in this way will also involve various side effects such as local anesthetic allergy, tissue and neurotoxicity, heart and central nervous system toxicity, etc., which has certain medical risks, and the operation is complicated and cumbersome.
[0003] Combining ancient TCM proven prescriptions and modern TCM theories, the developed TCM anesthesia preparations generally have the characteristics of low toxicity and side effects, safe and convenient medication, but also have the disadvantages of slow drug onset and unsuitable dosage control. For example, the authorized announcement number is CN104043146B (application number 201410288043.4) an invention patent for an anesthesia medicinal sponge and its preparation method. When using the invention, the anesthesia effect will be affected by the size and length of the operation. Therefore, a new traditional Chinese medicine anesthesia preparation is developed to better apply to Local anesthesia is necessary

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 tincture

[0026] Each raw material of the present invention is weighed according to the following parts by weight: 14 parts of Dingjiao, 4 parts of Heliconia, 13 parts of Salvia miltiorrhiza, 10 parts of keel, 10 parts of purslane, 7 parts of forsythia, 2 parts of menthol, and 10 parts of thistle.

[0027] The preparation process is as follows:

[0028] According to the aforementioned ratio, weigh the above traditional Chinese medicine components except menthol and pulverize them into coarse powder; place them in an airtight container, refrigerate and slowly add ethanol to make the alcohol content reach 60%, stir evenly, let stand for 72 hours, and filter Add an appropriate amount of 50% ethanol to the dregs, stir evenly, let it stand for 72 hours, and filter; combine the two filtrates, add menthol in the prescribed amount, an appropriate amount of glycerin and 50% ethanol, so that the crude drug amount reaches 0.4g / ml, stirred evenly, refrigerated for 24 h...

Embodiment 2

[0029] Example 2 tincture

[0030] Each raw material of the present invention is weighed according to the following parts by weight: 12 parts of Dingjiao, 3 parts of Heliconia, 12 parts of Salvia miltiorrhiza, 8 parts of keel, 8 parts of purslane, 6 parts of forsythia, 1 part of menthol, and 8 parts of thistle.

[0031] The preparation process is as follows:

[0032] According to the aforementioned ratio, weigh the above traditional Chinese medicine components except menthol and pulverize them into coarse powder; place them in an airtight container, refrigerate and slowly add ethanol to make the alcohol content reach 60%, stir evenly, let stand for 72 hours, and filter Add an appropriate amount of 50% ethanol to the dregs, stir evenly, let it stand for 72 hours, and filter; combine the two filtrates, add menthol in the prescribed amount, an appropriate amount of glycerin and 50% ethanol, so that the crude drug amount reaches 0.4g / ml, stirred evenly, refrigerated for 24 hours...

Embodiment 3

[0033] Example 3 tincture

[0034] Each raw material of the present invention is weighed according to the following parts by weight: 16 parts of Dingjiao, 5 parts of Heliconia, 14 parts of Salvia miltiorrhiza, 12 parts of keel, 12 parts of purslane, 8 parts of forsythia, 3 parts of menthol, and 12 parts of thistle.

[0035] The preparation process is as follows:

[0036] According to the aforementioned ratio, weigh the above traditional Chinese medicine components except menthol and pulverize them into coarse powder; place them in an airtight container, refrigerate and slowly add ethanol to make the alcohol content reach 60%, stir evenly, let stand for 72 hours, and filter Add an appropriate amount of 50% ethanol to the dregs, stir evenly, let it stand for 72 hours, and filter; combine the two filtrates, add menthol in the prescribed amount, an appropriate amount of glycerin and 50% ethanol, so that the crude drug amount reaches 0.4g / ml, stirred evenly, refrigerated for 24 h...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and particularly relates to a pharmaceutical composition for local anaesthesia. The pharmaceutical composition comprises solanum surattense, semen hyoscyami, radix salviae miltiorrhizae, dragon bone, herba portulacae, fructus forsythiae, menthol and cirsium japonicum. The pharmaceutical composition is precise in formula, reasonable in compatibility, small in side effect, convenient to use and capable of achieving sedation anesthesia, clearing away heat and toxic materials, eliminating stagnant blood and relieving pain, and is an effective drug for local anaesthesia.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for local anesthesia. Background technique [0002] Anesthesia is a medical method that temporarily deprives the patient of overall or local sensation through drugs or other methods to achieve painlessness and provides conditions for surgical treatment or other medical examination and treatment, mainly including general anesthesia, local anesthesia and compound anesthesia. Among them, local anesthesia is simple and safe, can keep patients awake, has little interference with physiological functions, and has few complications. It is suitable for small and medium-sized operations with relatively superficial limitations and is widely used in clinical practice. Currently clinical local anesthesia generally adopts Western medicine methods for anesthesia. Commonly used local anesthetics include esters such as procaine, bupivacaine, tetracaine an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61P23/02A61K35/02A61K31/045
CPCA61K36/81A61K9/0014A61K9/08A61K31/045A61K35/02A61K36/185A61K36/28A61K36/537A61K36/634A61K47/10A61K2236/333A61K2236/39A61K2300/00
Inventor 唐国萍
Owner 唐国萍
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