Method for making living tissues and organs

Abstract

The invention discloses a method for making living tissues and organs. The method is characterized by comprising the following steps: calculating medical image information, and converting the medical image information into three-dimensional image information; performing three-dimensional reconstruction of outer original appearances and inner micro-structures of the tissues and organs in combination with a reference structure in a tissue and organ database; and making the tissues and organs by adopting a material additive making process according to a three-dimensional mode, properly processing the surface of a physical model, and making the living tissues and organs through 3D printing. The method has the benefits that: the making speed of the living tissues and organs is rapid; the shapes of the inner micro-structures are precise; the bionic degree is high; the biological rejection is low; the medical biological nature is good; related technology gaps can be filled up; and particularly, relatively high social benefits and economic benefits can be generated.

Description

technical field [0001] The invention relates to the field of biomedicine, in particular to a method for making living tissues and organs. Background technique [0002] The failure and damage of tissues and organs is a major problem in clinical medicine, and its treatment methods mainly include organ transplantation, surgical repair, artificial substitutes, medical devices and drug therapy. Autologous organ transplantation is a conventional method of "injury to wound", and the donor area is limited, and there is a serious shortage of donor organs; artificial substitutes have biocompatibility problems. In recent years, the emergence of tissue engineering technology has effectively avoided the above disadvantages, and has increasingly become a medical treatment method widely recognized by people. [0003] Tissue engineering is to use the principles and methods of engineering science and life science to adsorb normal tissue cells cultured and expanded in vitro on a biomaterial ...

AI Technical Summary

Problems solved by technology

Although these traditional methods have also obtained relatively successful tissue engineering scaffolds, the performance of the tissue engineering scaffolds obtained by them is not ideal.

It is mainly manifested in the lack of mechanical strength, the low degree of interpenetration of pores, and the poor controllability of porosity and pore distribution, which will affect the growth of cells and the vascularization of tissues

No matter what method is used, the prepared stent does not have a consistent internal structure, and its external structure cannot match the anatomical structure of the patient's damaged tissue and organ, so that the requirements for individualized manufacturing and production of the stent cannot be realized.

[0005] In order to solve the technical bottleneck of the current artificial living tissue and organ, the present invention proposes a production method of living tissue and organ, which can solve the problems of shortage of donor organs and biological rejection in the transplantation process, and can be used in clinical practice. Scientific research, teaching experiments, etc., can not only fill the gaps in related technologies, but also produce greater social and economic benefits

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