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Chenxiang Lubailu medicine preparation

A pharmaceutical preparation, white dew technology, applied in the field of Chen Xianglu Bailu pharmaceutical preparations and its preparation, can solve the problems of low bioavailability, incomplete absorption, slow curative effect, etc., achieve better qi and pain relief, good bioavailability, and release high effect

Inactive Publication Date: 2016-01-20
KAMP PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional Chenxianglu Bailu tablets disintegrate slowly, absorb incompletely, have low bioavailability, and slow curative effect

Method used

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  • Chenxiang Lubailu medicine preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 (Chenxianglu Bailu tablets of the present invention)

[0039] prescription: 100g of licorice, 100g of tangerine peel, 38.2g of Chuanxiang, 8.3g of rhubarb, 9.2g of calamus, 110g of bismuth subnitrate, 33.7g of magnesium carbonate, 33.7g of magnesium oxide, and 67g of sodium bicarbonate.

[0040] Preparation:

[0041] 1) Firstly crush licorice, tangerine peel, chrysanthemum, rhubarb, and calamus into fine powder with a superfine pulverizer, then weigh the five-flavored Chinese medicine powder according to the prescription, and mix through a 200-300 mesh sieve;

[0042] 2) Take bismuth subnitrate to make colloidal bismuth through colloid mill, add warm distilled water and stir for 5-10 minutes to make bismuth subnitrate liquid;

[0043] 3) Weigh magnesium carbonate, magnesium oxide, sodium bicarbonate three flavor chemicals and starch according to the prescription and mix and stir;

[0044] 4) Mix 1) and 3), pass the material through a 40-120 mesh siev...

Embodiment 2

[0045] Example 2 (Commercially available Chenxianglu Bailu Tablets)

[0046] Prescription: licorice 100g, bismuth subnitrate 110g, tangerine peel 100g, magnesium carbonate 33.7g, Chuanxiang 38.2g, magnesium oxide 33.7g, rhubarb 8.3g, sodium bicarbonate 67g, Shichangpu 9.2g.

[0047] Preparation:

[0048] 1) Grind licorice, tangerine peel, chrysanthemum, rhubarb, and calamus into 80-mesh fine powder, then weigh five-flavored Chinese medicine powder according to the prescription, and pass through a 18-mesh sieve; weigh bismuth subnitrate, magnesium carbonate, and magnesium oxide according to the prescription , sodium bicarbonate four chemicals and starch are mixed and stirred, and passed through a 40-mesh sieve;

[0049] 2) Mix the materials in step 1) in the mixer for 5 minutes, add warm distilled water and stir for 5-10 minutes to make a suitable soft material. After sizing with a 14-mesh nylon mesh, the coarse particles are crushed with a dust mill (coarse mesh) Mix with ...

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Abstract

The invention discloses a Chenxiang Lubailu medicine preparation. The preparation is characterized in that the preparation is prepared from, by weight, 50-200 g of liquorice, 50-200 g of dried tangerine peel, 15-80 g of common vladimiria roots, 4-20 g of rhubarb, 5-20 g of acorus tatarinowii, 50-250 g of bismuth subnitrate, 15-70 g of magnesium carbonate, 15-70 g of magnesium oxide and 30-90 g of sodium bicarbonate. The medicine preparation is a composite preparation, and liquorice, dried tangerine peel, common vladimiria roots, rhubarb and acorus tatarinowii mainly have the treatment effects of invigorating the stomach and regulating the middle warmer and regulating the flow of qi to alleviate pain; bismuth subnitrate, magnesium carbonate, magnesium oxide and sodium bicarbonate mainly have the functions of neutralizing gastric acid, regulating qi and balancing the pH value of gastric juice after being dissolved in the stomach, and have a synergistic effect on treatment effects of the basic remedy. The preparation is simple in preparation technology, and the bioavailability of the medicine is greatly improved through superfine grinding.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations, and in particular relates to a Chenxianglu Bailu pharmaceutical preparation and a preparation process thereof. Background technique [0002] Chen Xianglu Bailu Tablets is a classic Chinese patent medicine, which mainly has the functions of invigorating the stomach, harmonizing the middle, regulating qi and relieving pain, etc. It is used for gastric ulcer, erosive gastritis, hyperacidity, acute and chronic gastritis, gastrointestinal neurosis and duodenitis, etc. However, the traditional Chenxianglu Bailu tablet disintegrates slowly, has incomplete absorption, low bioavailability, and slow curative effect. Contents of the invention [0003] The invention aims to provide a Chenxianglu Bailu pharmaceutical preparation with scientific composition, good release rate, high bioavailability and remarkable curative effect. [0004] In order to achieve the above-mentioned purpose of the inven...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61K9/28A61P1/04A61P1/00A61P25/00A61K33/10A61K33/08A61K33/00A61K33/24
Inventor 曾培安吴健民刘娟
Owner KAMP PHARMA
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