Preparation method for inclusion compound of probiotics-beta-cyclodextrin or derivative thereof

Abstract

The invention specifically discloses a preparation method for an inclusion compound of probiotics-beta-cyclodextrin or a derivative thereof. The preparation method is characterized in that every 1000 g of the inclusion compound of probiotics-beta-cyclodextrin or the derivative thereof comprises 3000 billions to 10000 billions of probiotics, and the rest of beta-cyclodextrin and the derivative thereof are prepared by the following method: (1) firstly, mixing the probiotics with the beta-cyclodextrin and the derivative thereof according to an equivalent progressive-increasing method, putting into a double-shaft paddle efficient mixer to stir for 300-480 seconds uniformly; (2) directly pressing the uniformly-stirred materials into particles of 8-10 meshes by adopting a dry-type granulator; (3) putting the prepared particles of 8-10 meshes into a counter-current cooler, cooling and drying for 8-12 minutes under the conditions with vibrational frequency of 25-33 times / minute, amplitude of 30 mm, air sucking amount of 13500-18000m<3> / h, and air pressure of greater than and equal to 200 mmHg, so that the moisture content is lower than 8%; (4) crushing the cooled and dried particles with a crusher until the particle diameter is 65-80 meshes, thereby preparing the inclusion compound of the probiotics-beta-cyclodextrin or the derivative thereof.

Description

technical field [0001] The invention relates to the processing field of feed and feed additives, in particular to a preparation method of a prebiotic-beta-cyclodextrin or a derivative inclusion compound thereof. Background technique [0002] In recent years, in the food industry, the concept of probiotics has appeared more and more frequently, and this concept has also penetrated into the feed and feed additive industry. As an alternative to antibiotics and growth hormones, prebiotics are increasingly used in the livestock industry. Prebiotics were defined by Fuller in 1989 as "Alive microbial feed supplement which beneficially affects the bost animal by improving its intestinal micl-bial balanct," that is, microbial live bacterial feed additives that provide benefits to the host by regulating the microbial balance in the host's intestinal tract. Prebiotics are a type of live microbial preparations that can be used to regulate the microecological balance of animal organisms...

AI Technical Summary

Problems solved by technology

Because the temperature during spray drying is too high, it is not suitable for the production of probiotic inclusion compounds

The freeze-drying method is suitable for the preparation of prebiotic inclusion compounds, but due to expensive equipment, another production line needs to be built, which undoubtedly increases the investment in equipment and increases production costs, so it is difficult for prebiotic inclusion compounds to be widely used in feed processing. application