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Medicine for treating phlegm-turbidity closed resistance type coronary heart disease and preparation method thereof

A technology for coronary heart disease and medicine is applied in the field of medicine for treating phlegm blocking coronary heart disease and its preparation, which can solve the problems of affecting myocardial infarction, affecting the curative effect of patients with coronary heart disease, stent fracture, etc., and achieves no toxic side effects and treatment course The effect of short, toned mid focus

Inactive Publication Date: 2015-05-27
任军
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it is also found that about 30% to 50% of the patients receiving this therapy will have restenosis in the coronary artery within six months after the operation, which has become a major problem that seriously affects the curative effect of patients with coronary heart disease. At the same time, the stent breaks in the body The problem is also becoming more and more prominent, which may affect the sudden occurrence of myocardial infarction

Method used

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Experimental program
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Effect test

preparation example Construction

[0081] When the dosage form of the medicine is powder injection, its preparation method comprises the following steps:

[0082] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulverizer and pulverized into a mixture composed of micron-sized particles with a volume average particle size of 0.1-10 μm and nano-sized particles with a volume-average particle size of less than 0.1 μm Powder, the powder yield of the mixed powder is at least 95%;

[0083]In the second step, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixed powder that is 3 to 5 times the mass of the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and put the ethanol solution in Stand still for 24-36 hours under the condition of 5°C-10°C, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, concentrate and dry, and put it into a superfi...

Embodiment 1

[0096] Embodiment 1 powder injection

[0097] The preparation process of the powder injection of the present invention is: take Angelica 250g, Jiangxiang 170g, Radix Paeoniae Alba 300g, Cynomorium cynomorium 200g, Guizhi 150g, Huixincao 170g, Asarum 120g, Lianzixin 320g, Scallop 240g, Trichosanthes 200g, 300g of bone fat, 30g of pinellia, 250g of amethyst, 150g of white mustard seed, 200g of Ophiopogon japonicus, 320g of mulberry branch, 30g of unique taste, 330g of turmeric, 200g of madder, 350g of cinnamon, 260g of floating wheat, 150g of astragalus, 220g of codonopsis, fried Atractylodes macrocephala 300g, 250g cress, 350g calcined keel, 240g camphor root, 340g citrus aurantium, 120g magnolia flower, 170g betel nut, 280g sea pine nut, 150g cypress kernel, 240g sala seed, 160g notopterygium, 350g fin thistle, 200g divine comedy, Side ears 190g and wood butterfly 120g;

[0098] In the first step, the raw medicinal materials are mixed in proportion, put into an ultrafine pulv...

Embodiment 2

[0101] Embodiment 2 oral liquid

[0102] The preparation process of the oral liquid of the present invention is: take Angelica 350g, Jiangxiang 220g, Radix Paeoniae Alba 300g, Cynomorium 240g, Guizhi 330g, Huixincao 200g, Asarum 320g, Lianzixin 130g, Scallop 250g, Trichosanthes 220g, 300g psoralen, 30g pinellia, 200g amethyst, 150g white mustard seed, 220g Ophiopogon japonicus, 320g mulberry branch, 30g unique taste, 350g turmeric, 200g madder, 330g cinnamon, 140g floating wheat, 200g astragalus, 150g codonopsis, fried 330g Atractylodes macrocephala, 220g cress, 350g calcined keel, 240g camphor root, 340g citrus aurantium, 200g magnolia flower, 250g areca nut, 150g sea pine nut, 300g cypress kernel, 220g sala seed, 140g notopterygium, 350g fin thistle, 170g divine comedy , side ears 250g and wood butterfly 150g;

[0103] In the first step, mix camphor root, citrus aurantium, magnolia officinalis, betel nut, sea pine nut, cypress kernel, sala seed, notopterygium, fin thistle, ...

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Abstract

The invention discloses a medicine for treating phlegm-turbidity closed resistance type coronary heart disease and a preparation method thereof. The medicine comprises the following raw medicinal materials: angelica sinensis, lignum dalbergiae odoriferae, white paeony root, cynomorium songaricum, cassia twig, rhodobryum roseum, asarum, lotus plumule, allium macrostemon, trichosanthes kirilowii maxim, fructus psoraleae, pinellia ternata, amethyst, semen brassicae, ophiopogon root, mulberry twig, lamiophlomis rotata, turmeric, rubia cordifolia, cinnamon, blighted wheat, astragalus, radix codonopsis, roasted rhizoma atractylodis macrocephalae, water dropwort, calcined keel, camphortree root, fructus aurantii, flower of official magnolia, betel nut, korean pine seed, semen boitae, semen aesculi, notopterygium, olgaea leucophylla, medicated leaven, oyster-cap fungus and oroxylum indicum. The medicine disclosed by the invention has the following beneficial effects: the medicine has the effects of warming and strengthening the heart-yang, promoting circulation and removing stasis, filling the heart fluid, dispersing the moisture, reconciling middle-Jiao and combing qi function, is mainly used for curing the phlegm turbidity closed resistance type coronary heart disease, and has the advantages of fast effectiveness, high effective rate, exact curative effect, short treatment course, zero toxic or side effect, low price and the like.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a medicine for treating phlegm-turbidity obstructive coronary heart disease and a preparation method thereof. Background technique [0002] Coronary heart disease, known as chest pain in ancient times, is the most common heart disease. It refers to myocardial dysfunction or organic disease caused by coronary artery stenosis and insufficient blood supply, so it is also called ischemic heart disease and ischemic heart disease. Coronary artery disease is the result of a variety of coronary artery disease, but coronary atherosclerosis accounts for the vast majority of coronary heart disease. [0003] The pathogenesis of coronary heart disease: most of the coronary heart disease is caused by organic stenosis or blockage of the arteries, also known as coronary atherosclerotic heart disease, the narrowing of the coronary arteries is mostly caused by the accumulation of fatty substan...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P9/10A61K35/02A61K33/14
Inventor 任军陶银英
Owner 任军
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