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Rare earth element containing hemodialysis membrane and preparation method thereof

A rare earth element, hemodialysis technology, used in semi-permeable membrane separation, chemical instruments and methods, membrane technology, etc., can solve problems such as unstable performance and affect dialysis efficiency, achieve good removal of toxins, good retention performance, and reduce activation. Effect

Inactive Publication Date: 2015-03-25
SUZHOU COSMETIC MATERIALS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] It can be seen that the biocompatibility of the polysulfone dialysis membrane is mainly realized by adding biocompatible functional polymers, and its performance is not stable, and long-term use will affect the dialysis efficiency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A hemodialysis membrane containing rare earth elements, the dialysis membrane is a hollow fiber membrane, including the following components in parts by mass: 35 parts of polysulfone, 12 parts of cellulose diacetate, 0.1 part of nano samarium trichloride, 4 parts of polyvinyl acetate Parts and 25 parts of solvent, the solvent is dimethylacetamide and lithium chloride, the mass ratio of the two is 1:1.

[0023] According to the preparation method provided by the present invention, the hemodialysis membrane containing rare earth elements is prepared, and the dry-wet method is adopted. The preparation steps are as follows:

[0024] (1) Take nano-samarium trichloride, dry it in vacuum, take it out, put it into the solvent, stir evenly, add polysulfone, diacetate fiber and toughening agent, stir ultrasonically for 5 minutes, put it into the spinning solution tank, Vacuum defoaming;

[0025] (2) Deionized water is used as the core fluid, and the core hydraulic pressure is 0....

Embodiment 2

[0031] A hemodialysis membrane containing rare earth elements, the dialysis membrane is a hollow fiber membrane, including the following components in parts by mass: 40 parts of polysulfone, 14 parts of cellulose diacetate, 0.2 parts of nano samarium trichloride, 5 parts of polyvinyl alcohol Parts and 30 parts of solvent, the solvent is dimethylacetamide and lithium chloride, the mass ratio of the two is 2:1.

[0032] According to the preparation method provided by the present invention, the hemodialysis membrane containing rare earth elements is prepared, and the dry-wet method is adopted. The preparation steps are as follows:

[0033] (1) Take nano-samarium trichloride, dry it in vacuum, take it out, put it into the solvent, stir evenly, add polysulfone, diacetate fiber and toughening agent, stir it ultrasonically for 5 minutes, put it into the spinning solution tank, Vacuum defoaming;

[0034] (2) Deionized water is used as the core fluid, and the core hydraulic pressure i...

Embodiment 3

[0040] A hemodialysis membrane containing rare earth elements, the dialysis membrane is a hollow fiber membrane, including the following components in parts by mass: 40 parts of polysulfone, 16 parts of cellulose diacetate, 0.3 parts of nano samarium trichloride, 7 parts of polyvinyl acetate Parts and 35 parts of solvent, the solvent is dimethylacetamide and lithium chloride, the mass ratio of the two is 3:1.

[0041] According to the preparation method provided by the present invention, the hemodialysis membrane containing rare earth elements is prepared, and the dry-wet method is adopted. The preparation steps are as follows:

[0042] (1) Take nano-samarium trichloride, dry it in vacuum, take it out, put it into the solvent, stir evenly, add polysulfone, diacetate fiber and toughening agent, stir it ultrasonically for 7 minutes, put it into the spinning solution tank, Vacuum defoaming;

[0043] (2) Deionized water is used as the core fluid, and the core hydraulic pressure i...

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Abstract

The invention provides a rare earth element containing hemodialysis membrane and a preparation method thereof, and relates to the field of biological materials. The hemodialysis membrane is a hollow fiber membrane and is 150 to 250 microns in average internal diameter and 28 to 46 microns in wall thickness. The hemodialysis membrane is prepared from the following components in parts by mass: 35 to 55 parts of polysulfone, 12 to 20 parts of diacetate fiber, 0.1 to 0.5 part of nanometer samarium chloride, 4 to 10 parts of a flexibilizer, and 25 to 50 parts of a solvent. The preparation method of the rare earth element containing hemodialysis membrane adopts a dry-wet preparation process. The rare earth element containing hemodialysis membrane is outstanding in biocompatibility, high in macromolecular protein intercepting performance and relatively high in small solute transmissivity, and is an ideal hemodialysis membrane material.

Description

technical field [0001] The invention belongs to the field of biological materials, in particular to a hemodialysis membrane containing rare earth elements and a preparation method of the hemodialysis membrane. Background technique [0002] Hemodialysis membrane uses the principle of semi-permeable membrane, with the help of the solute gradient, osmotic gradient and water pressure gradient on both sides of the membrane, to remove toxins and retain excess water in the body, and at the same time replenish the substances needed in the body, and maintain electrolytes and purpose of acid-base balance. [0003] Polysulfone membrane is a widely used synthetic membrane material, its membrane pore size and pore size distribution can be easily controlled by changing the composition of the casting solution, and for middle molecules in blood, such as microglobulin, and endotoxin Has a good cleaning effect. The biocompatibility can be effectively improved by heat-treating the initial fi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01D71/68B01D67/00B01D69/08
Inventor 张帆全春兰金仲恩
Owner SUZHOU COSMETIC MATERIALS
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