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Medical collagen gel and preparation method thereof

A technology of collagen and gel, which is applied in the field of medical biomaterials, can solve the problems of antibiotic resistance, easy recurrence of inflammation, and no repair function, so as to promote wound healing, reduce wound exudate, and relieve wound pain. painful effect

Inactive Publication Date: 2015-01-28
无锡贝迪生物工程股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are many products on the market to treat gynecological inflammation, most of which are spectrum antibacterial antibiotics and nano-silver antibacterial preparations. Long-term use of antibiotics will produce drug resistance, and while killing harmful bacteria, it also kills beneficial bacteria
Although the nano-silver antibacterial preparation has a strong bactericidal and antibacterial effect, it does not have a repair function, and it treats the symptoms but not the root cause, making inflammation prone to repeated attacks

Method used

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  • Medical collagen gel and preparation method thereof
  • Medical collagen gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Concentrate 4mg / mL collagen solution to 10mg / mL with polyethylene glycol, mix 1g polyvinylpyrrolidone to make 100mL, so that the content of collagen is 1%, the content of polyvinylpyrrolidone is 1%, and the balance For sterile water for injection. The above-mentioned raw materials are placed in a blender and fully stirred to form a homogenate, centrifuged to defoam, and after the preparation is completed, they are divided into disposable gel injectors or aluminum-plastic composite tubes to obtain medical collagen gel.

[0030] The medical collagen gel prepared above can be used to treat gynecological inflammations, such as cervicitis, cervical erosion, burns, abrasions, ulcers, bedsores or other skin inflammations. The properties of the prepared medical collagen are shown in Table 1, Table 2 and Table 3.

[0031] The specific usage and dosage for the treatment of cervical erosion embolism are as follows: firstly, the gel is pre-loaded into a disposable gel injection de...

Embodiment 2

[0034] The 4mg / mL collagen solution was concentrated to 20mg / mL with polyethylene glycol, mixed with 2.5g polyvinylpyrrolidone to make 100mL, so that the content of collagen was 2%, the content of polyvinylpyrrolidone was 2.5%, and the remaining The volume is sterile water for injection. The above-mentioned raw materials are placed in a blender and fully stirred to form a homogenate, centrifuged to defoam, and after the preparation is completed, they are divided into disposable gel injectors or aluminum-plastic composite tubes to obtain medical collagen gel. The properties of the prepared medical collagen are shown in Table 1, Table 2 and Table 3.

[0035] Concrete usage and consumption are with embodiment 1.

Embodiment 3

[0037] Concentrate the 4mg / mL collagen solution to 25mg / mL with polyethylene glycol, add 2g of polyvinylpyrrolidone to make 100mL, so that the content of collagen is 2.5%, the content of polyvinylpyrrolidone is 2%, and the balance For sterile water for injection. The above-mentioned raw materials are placed in a blender and fully stirred to form a homogenate, centrifuged to defoam, and after the preparation is completed, they are divided into disposable gel injectors or aluminum-plastic composite tubes to obtain medical collagen gel. The properties of the prepared medical collagen are shown in Table 1, Table 2 and Table 3.

[0038] Concrete usage and consumption are with embodiment 1.

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Abstract

The invention relates to a medical collagen gel and a preparation method thereof. The gel contains 1-3% by weight of collagen, 2.5-5% by weight of polyvinyl pyrrolidone, 0.5-3% by weight of a water-soluble polymer and 89-96% by weight of sterile water for injection. The medical collagen gel prepared by the method provided by the invention has good curative effects in treatment of female lower genital tract inflammation, cervicitis, cervical erosion, burns, scalds, bedsore infections, other wound infections and the like. In the aspect of treatment of gynecological inflammation, the gel has a good anti-inflammatory effect and moisturizing property and can regulate the pH value in a human body and maintain balance of an internal environment; and in the treatment aspect of repairing wounds, the gel can effectively reduce inflammation, reduce wound secretions, can be closely combined with newborn wounds to naturally form films to temporarily replace skin epidermis, prolongs the replacement time, reduces the suffering of the wounds, promotes the healing of the wounds and reduces scarring.

Description

technical field [0001] The invention relates to a medical collagen gel and a preparation method thereof, belonging to the field of medical biological materials. Background technique [0002] Gynecological vaginitis, cervicitis, and cervical erosion are common and frequently-occurring diseases in gynecological diseases. After women get sick, they have unbearable vaginal itching, increased vaginal secretions with peculiar smell, and repeated attacks of cervical erosion, which seriously affect women's physical and mental health. Gynecological inflammation is mainly caused by the destruction of the internal vaginal ecological environment, pH imbalance or local damage to the cervix. Therefore, effective anti-inflammation, repairing the internal environment balance and cervical damage, and restoring the pH value of the body to normal are the complete eradication of gynecological inflammation. effective means. At present, there are many products on the market to treat gynecologica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K38/39A61P17/02A61P29/00A61P15/00A61P15/02A61K31/79
Inventor 任伟业陆金婷赵颖林芳
Owner 无锡贝迪生物工程股份有限公司
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