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A kind of deer medicine buccal tablet and preparation method thereof

A technology of buccal tablet and deer medicine, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, antipyretics, etc., to achieve high medicinal value, low loss, and good absorption

Active Publication Date: 2017-03-22
SHENNONGJIA SHENLIN BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

By searching the existing technologies at home and abroad, it is found that there is no literature report on the preparation of deer medicine buccal tablets with deer medicine as the main ingredient.

Method used

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  • A kind of deer medicine buccal tablet and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A deer medicine buccal tablet, the optimum content of which is made of the following raw materials in weight percentage: deer medicine superfine powder 63%, isomalt 15%, maltodextrin 10%, magnesium stearate 4.96%, microcrystalline cellulose 7%, potassium copper chlorophyllin 0.04%.

[0024] The preparation method of described deer medicine buccal tablet comprises the following steps:

[0025] (1) Clean the deer medicine, use 0.08% (W / V) citric acid and 0.3% (W / V) zinc acetate mixed solution to blanch the deer medicine at 90°C for 6 minutes, take it out and store it at -40 Vacuum freeze-drying at ℃ for 4 hours, adding to a traditional Chinese medicine ultrafine pulverizer, and ultrafinely pulverizing to a particle size of more than 300 mesh, so that the cell wall breaking rate is greater than 95% to obtain ultrafine powder;

[0026] (2) Add 90% ethanol of 3 times the weight of the superfine powder to the superfine powder obtained in step (1), ultrasonically extract for ...

Embodiment 2

[0031] A buccal tablet of deer medicine, the optimal content of which is made of the following raw materials in weight percentage: 50% deer medicine superfine powder, 20% isomalt, 15% maltodextrin, 7.95% magnesium stearate, microcrystalline cellulose 7%, potassium copper chlorophyllin 0.05%.

[0032] The preparation method of described deer medicine buccal tablet comprises the following steps:

[0033] (1) Clean the deer medicine, use 0.05% (W / V) citric acid and 0.1% (W / V) zinc acetate mixed solution to blanch the deer medicine at 85°C for 4 minutes, take it out and store it at -35 Vacuum freeze-drying at ℃ for 4 hours, adding to a traditional Chinese medicine ultrafine pulverizer, and ultrafinely pulverizing to a particle size of more than 300 mesh, so that the cell wall breaking rate is greater than 95% to obtain ultrafine powder;

[0034](2) Add 90% ethanol 4 times the weight of the ultrafine powder to the superfine powder gained in step (1), ultrasonically extract 2h, fil...

Embodiment 3

[0039] A deer medicine buccal tablet, the optimal content is made of the following raw materials in weight percentage: 70%, isomalt 10%, maltodextrin 8%, magnesium stearate 4%, microcrystalline cellulose 7.98%, chlorophyll Copper potassium salt 0.02%.

[0040] The preparation method of described deer medicine buccal tablet comprises the following steps:

[0041] (1) Clean the deer medicine, use 0.1% (W / V) citric acid and 0.5% (W / V) zinc acetate mixed solution to blanch the deer medicine at 95°C for 8 minutes, take it out and store it at -25 Vacuum freeze-drying at ℃ for 4 hours, adding to a traditional Chinese medicine ultrafine pulverizer, and ultrafinely pulverizing to a particle size of more than 300 mesh, so that the cell wall breaking rate is greater than 95% to obtain ultrafine powder;

[0042] (2) Add 90% ethanol of 3.5 times the weight of superfine powder to the superfine powder obtained in step (1), ultrasonically extract 2h, filter, repeat 3 times, merge the filtrat...

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Abstract

The invention discloses a smilacina japonica buccal tablet and a preparation method thereof. The preparation method comprises the following steps: granulating bulk pharmaceutical chemicals: smilacina japonica superfine powder, isomaltitol, maltodextrin, magnesium stearate and microcrystalline cellulose in a wet process manner and then tabletting to obtain a buccal tablet. The prepared smilacina japonica buccal tablet is high in medicinal values, and can be absorbed through oral mucosa to directly act on the throat part, so that the functions of clearing and nourishing the throat can be enhanced, and the smilacina japonica buccal tablet has the effects of tonifying qi and kidney, dispelling wind and eliminating dampness, promoting blood circulation to restore menstrual flow, resisting tumor and the like, and is a medicinal and edible dual-use healthy product; the preparation method is simple in preparation technology, easy to operate, small in loss, capable of easily realizing industrial production, all active ingredients of precious herbs can be retained by replacing smilacina japonica superfine powder prepared by adopting the traditional technology, with superfine powder, the smilacina japonica buccal tablet is good to absorb and high in bioavailability, active ingredients can be completely utilized through twice complex enzyme fermentation, so that the usage amount of herbs can be reduced, medicinal materials can be saved, and the precious herbs can be reasonably utilized.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine or health food, in particular to a deer medicine buccal tablet and a preparation method thereof. Background technique [0002] Deer medicine is the dried rhizome of Smilacina japonica A.G ray, a plant of the genus Smilacina japonica A.Gray in the family Liliaceae, also known as nine floors and partial head seven. The young stems and leaves of many species of deer medicine plants are popular wild vegetables, and some rhizomes can be used as medicine, which is a commonly used traditional Chinese medicine in our country. It is recorded in "Dictionary of Chinese Medicine" that its nature and flavor are "sweet, bitter, warm, and non-toxic". Irregularities, carbuncle, furuncle, swollen poison and bruises, etc. There are about 25 species of deer medicine in the world, distributed in eastern Asia, Siberia, Russia, and North America to Central America. There are 14 species and 2 vari...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K9/20A23L33/00A61P39/00A61P29/00A61P35/00A61P15/00
CPCA23V2002/00A61K9/2054A61K36/896A61K2236/15A61K2236/333A61K2236/39A61K2236/51A23V2250/51084A23V2250/5114A23V2250/6416A23V2200/30A23V2200/308
Inventor 郭永兵王兴林李冬生向劲松杜永鹏
Owner SHENNONGJIA SHENLIN BIOTECH CO LTD
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