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Multifunctional bioceramic orbital implant as well as preparation technology and application thereof

A technology of bioceramics and preparation process, which is applied in the medical field and can solve problems such as orbital bone wear and impact

Active Publication Date: 2014-08-06
卢建熙 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still some issues to be resolved: ① How does the vascularization of porous materials and the quality of tissue ingrowth affect postoperative outcomes? ② How to avoid wear and tear on the orbital bone formed by the hard prosthetic platform? ③How to fix the oculodynamic muscle to the proper position and method of the prosthesis during the operation? The present invention aims to provide solutions to the above problems

Method used

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  • Multifunctional bioceramic orbital implant as well as preparation technology and application thereof
  • Multifunctional bioceramic orbital implant as well as preparation technology and application thereof
  • Multifunctional bioceramic orbital implant as well as preparation technology and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: Set the final product as The hydroxyapatite (powder shrinkage rate 10%) bioceramic prosthetic eye platform. Select stainless steel to prepare the metal positive die mold, the required metal ball diameter=20*(1+0.10)=22mm, and the height of the ball holder, the inner diameter and the outer diameter are respectively 11, 22 and 66mm for processing ( Figure 4 ). Put the metal ball into the ball holder on the glass, the outer diameter of the jacket matches the ball holder and the plastic casing with a height of 10cm, pour 200ml of slurry containing 60% gypsum powder and 40% water, and solidify and demould to form a gypsum female mold . The female molds are paired and fixed in pairs to form a spherical cavity ( ), one of the female molds rotates at the lowest part of the concave The through hole is used to load the pore forming agent ( Figure 5 ).

Embodiment 2

[0029] Example 2: Will Pour the PMMA pearl particles of μm into the composite female mold cavity of Example 1, add 8ml of acetone after checking the filling, add 20ml of pure water after 2 minutes, rinse and fix it into a spherical pore-forming scaffold, and dry it at 70°C for 48 hours. The hydroxyphosphate slurry was injected into a plaster mold loaded with a dry pore-forming bracket, and dried at 50°C for 48 hours to demould into a ceramic body. The ceramic body is baked at 300°C for 12 hours in a debinding furnace to remove organic matter, and sintered at 1200°C for 4 hours in a sintering furnace Hydroxyapatite homogeneous porous bioceramic prosthetic eye platform ( figure 1 Middle a).

Embodiment 3

[0030] Example 3: Prepare a spherical pore-forming stent according to the method in Example 2, and bake at 50°C for 12 hours to retain 20% of the water in the center of the sphere; then inject the tricalcium phosphate slurry into the plaster mold loaded with the pore-forming stent, Dry at 50°C for 48 hours to demould into a ceramic green body; the green body is baked at 300°C for 12 hours in a debinding furnace to remove organic matter, and sintered at 1100°C for 4 hours in a sintering furnace to form Tricalcium Phosphate Slurry Hollow Porous Bioceramic Prosthetic Eye Platform ( figure 1 Middle b).

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PUM

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Abstract

The invention relates to a multifunctional bioceramic orbital implant and a preparation technology thereof. The multifunctional bioceramic orbital implant is characterized in that a standard spherical porous bioceramic is prepared through accurate control of a mould and a pore-forming bracket; the surface structure or / and internal structure of the orbital implant is / are adjusted so as to enable the orbital implant to have different performance and functions. The homogeneous, hollow and sewable porous bioceramic orbital implants, and a gradient porous bioceramic orbital implant can be prepared through the preparation technology provided by the invention; the orbital implant has the advantages as follows: the material structure meets requirements of tissue growth and vascularization, so that the orbital implant can form permanent biological integration in an organism; the high-porosity material is relatively light in weight, so that the retaining of the mobility of the orbital implant is facilitated; the gradient porous bioceramic structure is adopted, so that the surface roughness can be reduced greatly, and abrasion to orbital bones bythe implanted orbital implant is reduced effectively; the sewable structure is adopted, so that tissue sewing and fixation are facilitated, especially the fixation of the dynamic muscle of an eyeball on the orbital implant is facilitated. The orbital implant provided by the invention is used for body repairing abouteyeball missing and psychic trauma improvement in the medical field of ophthalmology.

Description

technical field [0001] The invention relates to a porous bioceramic prosthetic eye platform with different structures and different properties and a manufacturing process thereof. The artificial eye platform is mainly used in the medical field. Background technique [0002] Patients who had to have their eyeballs removed due to tumors, trauma, infection, etc., failed to implant an artificial eye platform in time after the operation, making the mental pain caused by the loss of eyeballs far greater than the physical trauma. As the need exists, prosthetic eye repair technology has been formed, including artificial eye platform (also known as artificial eye seat or artificial eye fetus, orbital implant) implantation, that is, implanting a spherical artificial implant after removing the eyeball from the affected eye. body, and on its surface a layer of conjunctiva and the preparation of prosthetic eye. The prosthetic eye platform can play the role of filling and movement hub. I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/56A61L27/10A61F2/14
Inventor 卢建熙卢霄
Owner 卢建熙
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