Astragalus and ginseng powder submicron powder, and manufacturing method and application thereof

An ultra-fine powder and ultra-fine technology, used in powder delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problem of single processing and use methods of Chinese herbal medicine, affecting the quality and therapeutic effect of traditional Chinese medicine, and insufficient release of active ingredients, etc. problem, to achieve the effect of complete release of active ingredients, easy dissolution and absorption, and easy implementation of the method

Inactive Publication Date: 2014-05-14
INST OF OCEANOLOGY - CHINESE ACAD OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

my country has a long history of using Chinese herbal medicines to treat aquatic animal diseases, but the processing and use methods of Chinese herbal medicines for fishing are still very single, most of them are mainly coarsely crushed powders, or boiled and then splashed, resulting in large doses and rough dosage forms. , poor appearance and other deficiencies, the active ingredients cannot be fully released, and the bioavailability is low, which seriously affects the quality and therapeutic effect of traditional Chinese medicine, and restricts its clinical application

Method used

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  • Astragalus and ginseng powder submicron powder, and manufacturing method and application thereof
  • Astragalus and ginseng powder submicron powder, and manufacturing method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Qishen powder superfine powder, by weight percentage, astragalus 42%, ginseng 29%, licorice 29%.

[0023] Preparation:

[0024] (1) Drying: Wash the raw materials astragalus, ginseng and licorice, and then dry them at a constant temperature at 60°C to keep the water content below 8%; make them into 3-5cm long sections for later use.

[0025] (2) Coarse pulverization: Coarse pulverization with a traditional Chinese medicine pulverizer to pass through a 50-80 mesh sieve to obtain coarse powder;

[0026] (3) First-class ultrafine powder (impact mill ultrafine powder): The graded impact mill uses the violent impact between the hammer head on the high-speed rotating body and the material, and at the same time, it is impacted at the gap between the impact hammer head and the ring gear. , abrasion, shearing, to achieve ultra-fine crushing of materials, and the particle size and output of the product can be adjusted by changing the speed and wind speed of the classifier. Thro...

Embodiment 2

[0031] The clinical effect of preparation of the present invention is verified by following test:

[0032] 1. Experimental animals

[0033] The juvenile Litopenaeus vannamei was used as the experimental object. The juvenile Litopenaeus vannamei was artificially propagated with high-quality shrimp seedlings provided by the nursery factory, and raised to an appropriate size. Individuals with normal appearance and strong physique were selected as the experimental shrimp. It is a square glass fiber reinforced plastic water tank, all of which adopt automatic circulating water type. The seawater used in the experiment is seawater filtered through the underground sand layer, the salinity is 28-33ppt, and the pH is 8.0-8.2.

[0034] 2. Experimental design

[0035] There were 4 treatments in the experiment, 3 replicates for each treatment, and 100 prawns were stocked in each tank. The experimental basal feed design is based on the prawn feed formula recommended by the National Resea...

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Abstract

The invention relates to the field of fishery medicine agents, in particular to astragalus and ginseng powder submicron powder, and a manufacturing method and application of the astragalus and ginseng powder submicron powder. The astragalus and ginseng powder submicron powder is composed of, by weight, 40% to 50% of astragalus, 25% to 35% of ginseng and 25% to 35% of radix glycyrrhizae. The astragalus and ginseng powder submicron powder is reasonable in formula, capable of completely releasing effective constituents, small in additive amount, quick in cure effect, obvious in effect, free of toxic and side effect, easy to implement, and suitable for large-scale production. Long-term breeding experimental results show that prawns are bred through fodders with the astragalus and ginseng powder submicron powder prepared through the method, the growth performance and the non-specificity immune index of the prawns are remarkably improved, the consumption can be remarkably reduced by three to four times compared with ordinary coarsely-ground traditional Chinese medicine preparations in the current market, and therefore the effects of promoting growth and enhancing immunity are achieved.

Description

technical field [0001] The invention relates to the field of fish medicine preparations, in particular to a superfine powder of Qishen powder and its preparation method and application. Background technique [0002] At present, my country's aquaculture industry is developing very rapidly, and the development and use of fishery medicines are getting more and more attention in aquaculture. Although the single use of antibiotics and chemical drugs to treat aquatic animal diseases has achieved certain results, it has also brought many negative effects. Extensive use of chemical drugs will pollute the breeding environment, long-term use of antibiotics will enhance the resistance of pathogenic bacteria, and drug residues in aquatic animals will greatly reduce the quality and safety of aquatic products. Chinese herbal medicine has many advantages such as naturalness, nutrition, enhancing immune function, anti-stress, anti-microbial, repelling (killing) insects, two-way regulation,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/484A61K9/14A61P37/04A61P31/04A61P31/12
Inventor 王宝杰王安林王雷刘梅蒋克勇
Owner INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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