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Parasite expelling oil emulsion for veterinary use and preparation method thereof

An oil emulsion and emulsifier technology, which is applied in the field of veterinary anthelmintics and its preparation, can solve the problems of single function and poor stability, and achieve the effects of uniform drug distribution, improved stability, and improved stability

Active Publication Date: 2014-04-23
HARBIN QIAN HE ANIMAL DRUGS MFR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims to solve the technical problems of poor stability and single function of the existing abamectin products, and provides a kind of veterinary insect repellent oil emulsion and its preparation method

Method used

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  • Parasite expelling oil emulsion for veterinary use and preparation method thereof
  • Parasite expelling oil emulsion for veterinary use and preparation method thereof
  • Parasite expelling oil emulsion for veterinary use and preparation method thereof

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specific Embodiment approach 1

[0014] Specific embodiment one: the veterinary insect repellent oil emulsion of this embodiment is composed of avermectin, febantel, piperazine citrate, vegetable oil, emulsifier, surfactant, 2,6-di-tert-butyl - Emulsion composed of 4-methylphenol, chlorobutanol and water, wherein every 1000mL of veterinary insect repellent oil emulsion contains 20-200g of avermectin, 50-300g of febantel, and piperazine citrate 10~100g, vegetable oil 200~500ml, emulsifier 10~60ml, surfactant 10~50ml, 2,6-di-tert-butyl-4-methylphenol 1~5g, chlorobutanol 5~10g, the rest for water.

specific Embodiment approach 2

[0015] Embodiment 2: This embodiment is different from Embodiment 1 in that the vegetable oil is soybean oil or castor oil. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0016] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is that the emulsifier is one of acacia, lecithin, magnesium stearate and aluminum hydroxide or a combination of several of them in any ratio . Others are the same as in the first or second embodiment.

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Abstract

The invention discloses parasite expelling oil emulsion for veterinary use and a preparation method thereof, relating to a parasite expelling medicine for veterinary use and a preparation method thereof and solving the technical problems of poor stability and single function of the traditional abamectin product. The parasite expelling oil emulsion for veterinary use is composed of abamectin, febantel, piperazine citrate, vegetable oil, an emulsifier, a surfactant, 2,6-di-tert-butyl-4-methyl phenol, chlorobutanol and water. The preparation method comprises the following steps: adding the emulsifier, the febantel and the abamectin into warm vegetable oil at first, then adding the 2,6-di-tert-butyl-4-methyl phenol and the chlorobutanol, and stirring to obtain a solution A; adding the piperazine citrate into water, heating and adding the surfactant, and stirring to obtain a solution B; and cooling the solutions A and B, and mixing the solutions A and B to obtain the parasite expelling oil emulsion for veterinary use. The parasite expelling oil emulsion for veterinary use is good in stability, can be used to kill gastrointestinal nematodes, lung nematodes as well as ectoparasites and hemoflagellate protozoa of livestock, poultry or pets.

Description

technical field [0001] The invention relates to a veterinary anthelmintic and a preparation method thereof. Background technique [0002] With the development of animal husbandry, pigs, cattle, sheep, chickens and other animals are intensively raised. Under such intensive feeding conditions, parasitic diseases are more likely to develop and spread. Therefore, it is particularly important to drive out parasites inside and outside animals and promote healthy growth of animals. There are many varieties of veterinary anthelmintics on the market now. [0003] Abamectin has a good repelling and killing effect on animal internal and external parasites, especially arthropods and internal nematodes. It is mainly used to drive away gastrointestinal nematodes, lung nematodes and ectoparasites of cattle, sheep and other animals. At present, the dosage forms of Abamectin injection, Abamectin solution and other products include powder, tablet, premix, oral liquid and injection, etc., a...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K9/107A61P33/10A61P33/14A61P33/00A61K31/27A61K31/495
Inventor 于洪水朱斌
Owner HARBIN QIAN HE ANIMAL DRUGS MFR
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