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External traditional Chinese medicine preparation for treating chronic nasosinusitis and preparation method thereof

A technology for chronic rhinosinusitis and external preparations, which is applied in the field of medical preparations, can solve the problems of patients unable to adhere to systemic treatment, long treatment time for chronic rhinosinusitis, and patients' troubles and pains. The effect of stagnation and short healing time

Inactive Publication Date: 2014-04-16
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The course of the disease is long, it is easy to recur, and it is not easy to be completely cured, which often brings troubles and pains to patients.
At present, there are no ideal therapeutic drugs (such as antibacterial and anti-inflammatory) and methods except nasal endoscopic surgery at home and abroad, especially the control of recurrence is more difficult
[0004] In recent years, the wide application of CT has played a vital role in the diagnosis of chronic sinusitis. However, due to the long treatment time of chronic sinusitis (more than 4 weeks of antibiotics, 3 to 6 months of topical glucocorticoids, and more than 4 weeks of mucus drainage agents) )
As adjuvant therapy, negative pressure replacement and maxillary sinus puncture are often unacceptable, and the curative effect is uncertain. Many patients cannot adhere to systematic treatment, which seriously affects the curative effect.
For functional sinusitis surgery, the operation and postoperative oral cleaning are both painful, and patients cannot cooperate, which affects the curative effect, making chronic sinusitis a clinically intractable disease

Method used

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Examples

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preparation example Construction

[0042] The preparation process of the spray of the present invention is as follows: 1200g of all raw materials cocklebur, 1200g Cyperi, 1300g Houttuynia, 1400g Magnolia, 1300g Angelica dahurica, 1300g Nepeta; 1300g; Bletilla striata 1400g, Fangfeng 1200g, frankincense 1300g, all the raw medicinal materials are steam-distilled first to obtain crystals, set aside, then put the extracted dregs into 10 times the amount of ethanol, heat and reflux for extraction twice, each time 1 ~ 2 hours, extract the active ingredient, combine the 2 extracts and filter and let stand; combine the above two filtrates, recover ethanol under reduced pressure and concentrate until the concentration of the drug solution is 0.4g crude drug / mL. After suction filtration, the relative density of the filtrate 1.06 at about 20°C; the above-mentioned filtrate is eluted with 10 times the volume of the resin column with deionized water or distilled water, and then eluted with 95% ethanol with 5 times the volume...

specific Embodiment 1

[0093] Specific embodiment 1: Liu, man, 22 years old, went to a doctor in May, 2007. Self-report: Sensitive nose, often feeling stuffy, often holding back headaches, must prepare nose drops for reading and studying. After dropping it, it relieved the stuffy nose immediately, but the stuffy nose remained after a while. 5 days ago due to a cold, she kept sneezing and had a runny nose. Symptoms: nasal congestion, yellow pus discharge, slight odor, swelling pain in the forehead, tenderness in the brow bone, fever, body temperature 38.6°C, bilateral inferior turbinate swelling , mucous membrane bright red. Red tongue, yellow fur, floating pulse. Syndrome belongs to: wind-heat stagnation of the lung type, treatment is suitable for clearing wind and heat, dispelling tears and clearing the orifices. Recipe: Xanthium 13g, Rhizoma Cyperi 13g, Houttuynia cordata 12g, Magnolia 14g, Angelica dahurica 14g, Schizonepeta 12g; Borneol 13g, Mint 12g, Asarum 13g, Goose Herb 13g; Bletilla stri...

specific Embodiment 2

[0094] Specific embodiment 2: Han, female, 28 years old. Self-reported love of colds, because the patient’s immunity is low, once a cold catches a cold, it will cause congestion and swelling of the nasal mucosa, which can lead to sinusitis; cause a large amount of viscous or purulent nasal discharge, nasal congestion, headache, dizziness, acute sinusitis with fever and systemic symptoms ; Nasal examination showed mucous membrane congestion, swelling, nasal cavity or posterior nares with more viscous or purulent secretions. X-ray films have positive findings, such as increased sinus cavity density, dense shadows of different thicknesses on the edge of the sinus cavity, and fluid levels in the cavity. Diagnosed as liver and gallbladder failure in catharsis, gallbladder fire along the meridian and injuring the nasal orifice, which can burn qi and blood, turn into pus and become chronic sinusitis. Recipe: Xanthium 13g, Rhizoma Cyperi 13g, Houttuynia cordata 12g, Magnolia 14g, Ang...

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Abstract

The invention discloses an external traditional Chinese medicine preparation for treating chronic nasosinusitis. The external preparation comprises the following raw material medicines in parts by weight: 10-20 parts of Siberian cocklebur, 10-20 parts of rhizoma cyperi, 10-20 parts of Houttuynia cordata, 10-20 parts of flos magnoliae, 10-20 parts of radix angelicae, 10-20 parts of Schizonepeta, 10-20 parts of borneol, 10-20 parts of mint, 10-20 parts of asarum, 10-20 parts of Centipeda minima, 10-20 parts of bletilla striata, 10-20 parts of divaricate saposhnikovia root and 10-20 parts of frankincense. The nasal lesions can be subjected to optimal stimulation; the external preparation has the effects of dredging the meridian, eliminating qi-blood stagnation and promoting blood flow, the effects of strengthening the body resistance to eliminate pathogenic factors are achieved, and the clinical curative effect is the best. The external traditional Chinese medicine preparation is simple in formula, simple and convenient in preparation process, small in toxic or side effect and convenient in administration, and is easy to prepare and low in cost.

Description

technical field [0001] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to an external Chinese medicine preparation for treating chronic sinusitis and a preparation method thereof. Background technique [0002] Chronic sinusitis is a common disease in otolaryngology. Mucosa edema caused by infection and allergy is the main cause of sinusitis. In addition to nasal symptoms such as purulent nasal discharge, nasal obstruction, postnasal drip, and nosebleeds, symptoms are often accompanied by adjacent organ symptoms, systemic and secondary symptoms, so other departments are often consulted first. As a result, misdiagnosis or treatment is not standardized, and finally chronic sinusitis is formed. Because the symptoms of chronic sinusitis are mild or asymptomatic, they are often easily overlooked. Modern medicine believes that its pathogenesis is as follows: (1) acute rhinitis repeatedly shows up and f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P11/02A61K31/045
Inventor 不公告发明人
Owner QINGDAO HENGBO INSTR
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