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A kind of traditional Chinese medicine preparation for treating migraine of phlegm turbid internal resistance type and preparation method thereof

A traditional Chinese medicine preparation, phlegm turbidity internal resistance technology, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as difficulty in obtaining satisfactory curative effects, and achieve the effects of less toxic side effects and definite curative effects

Inactive Publication Date: 2015-11-18
姜秀娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine generally uses anti-inflammatory, analgesic and calcium channel blockade methods in the treatment of migraine, but it is difficult to achieve satisfactory clinical results

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0039] The present invention also provides the preparation method of above-mentioned Chinese medicine preparation, the dosage form of described Chinese medicine preparation is a tablet, and its preparation method comprises the following steps:

[0040] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 75% to 85% that is 2 to 3 times the mass of the mixture, heat and reflux for 1 to 2 hours, extract, and filter to obtain the first Extract solution, filter the medicinal dregs obtained, then add ethanol with an alcohol concentration of 75% to 85% relative to the mass of the medicinal dregs, heat and reflux for 30 to 40 minutes, extract, filter to obtain the second extract, and the first The extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0041] The second step: place the dry paste obtained in the...

Embodiment 1

[0047] Embodiment 1: tablet

[0048] Take 160g of nandina root, 120g of spider plant, 60g of crab seven, 70g of pinellia, 180g of rock green orchid, 110g of usnea, 80g of honeycomb grass, 140g of red-headed fairy, 280g of hibiscus, 220g of cat's claw, 170g of throat grass, 140g dew grass and 90g red fruit nan;

[0049] Prepare as follows:

[0050] The first step: mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 75% that is 3 times the mass of the mixture, heat and reflux for 1 hour, extract, filter to obtain the first extract, and filter the obtained drug Then add ethanol with an alcohol concentration of 75% that is twice the mass of the dregs, heat and reflux for 30 minutes, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under reduced pressure to remove ethanol solvent, dried to obtain a dry paste;

[0051] The second step: place...

Embodiment 2

[0053] Embodiment 2: Granules

[0054] Take 180g of nandina root, 140g of spider plant, 70g of crab seven, 60g of pinellia, 160g of rock green orchid, 130g of usnea, 60g of honeycomb, 120g of red-headed fairy, 260g of hibiscus, 240g of cat's claw, 180g of throat grass, 120g dew grass and 70g red fruit nan;

[0055] Prepare as follows:

[0056] The first step: mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 3 times that of the mixture and be 85% ethanol, heat to boiling and reflux for 3 hours, filter, and slow down the mixture at a rate of 2ml per minute by percolation method. Slow percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.06Mpa to a paste with a relative density of 1.07 at 80°C, spray dry, the inlet air temperature of the spray dryer is 150°C, and the outlet air temperature is 80°C. Then pulverized into powder to make dry cream powder;

[0057] Step 2: Add 0.3 times of s...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for treating stagnation of endogenous retention of phlegm type migraine and a preparation method thereof. The traditional Chinese medicine preparation comprises the following active pharmaceutical ingredients: root of common nandina, fewflower lysionotus herb, rhizoma arisaematis, rhizoma pinelliae preparatum, herb of rupestrine dragonhead, usnea, herb of ceylon leucas, herb of pubescent blumea, fruit of shrubalthea, radix ranunculi ternati, umbellate rock jasmine, all-grass of blackspiked lovegrass and root of redfruit actionodaphne. The traditional Chinese medicine preparation has effects of drying dampness and resolving phlegm and calming the adverse-rising energy and relieving pain, has obvious curative effects on the phlegm obstruction type migraine, and has small toxic and side effects.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine preparation for treating phlegm internal resistance type migraine and a preparation method thereof. Background technique [0002] Migraine is a common chronic neurovascular disease. It usually occurs in children and adolescence, and reaches the peak in young and middle-aged adults. It is more common in women, and the ratio of male to female patients is about 1:2~3. % to 10%, often with a genetic background. Migraine is a recurrent disease with a tendency to develop in families. It is manifested as paroxysmal hemilateral throbbing headache, accompanied by nausea, vomiting and photophobia, which recurs after a period of rest. Headache relief in a quiet, dark environment or after sleep. It may be accompanied by neurological and mental dysfunction before or during the onset of headache. [0003] ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P25/06
Inventor 姜秀娟陈红
Owner 姜秀娟
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