Traditional Chinese medicinal enteric-coated tablets for treating proctitis, colitis and irritable bowel syndrome, as well as preparation method and application thereof

Abstract

The invention provides traditional Chinese medicinal enteric-coated tablets for treating proctitis, colitis and irritable bowel syndrome, as well as a preparation method and application thereof. Active components for preparing the traditional Chinese medicinal enteric-coated tablets comprise the following traditional Chinese medicinal raw materials in parts by weight: 200-800 parts of smoked plum, 50-400 parts of golden thread, 50-400 parts of dried ginger, 50-400 parts of costustoot, 50-300 parts of pericarpium papaveris, and 50-300 parts of rhizoma corydalis. Clinical researches on ulcerative colitis prove that, the traditional Chinese medicinal enteric-coated tablets have a cure rate of 59.1 percent in a treatment group, and a total effective rate of 98.1 percent. Clinical researches on irritable bowel syndrome prove that traditional Chinese medicinal enteric-coated tablets have a complete remission rate of 67.8 percent in the treatment group, and a total effective rate of 95.2 percent. In clinical researches on proctitis, the traditional Chinese medicinal enteric-coated tablets are used for treating 36 cases, wherein 32 cases are cured, 3 cases are improved, 1 case is invalid, and the total effective rate is 88.8 percent. The researches prove that the enteric-coated tablets have remarkable advantages and improvement in treatment after the preparation and dose forms are improved, and are advantageous to clinical application. The traditional Chinese medicinal enteric-coated tablets are easily available in raw materials, simple in method and pollution free, is suitable for industrial production, and has higher application value.

Description

Technical field [0001] The invention relates to traditional Chinese medicines, in particular to colon-positioning enteric-coated tablets of traditional Chinese medicines, in particular to a traditional Chinese medicine enteric-coated tablets for treating colitis, proctitis and irritable bowel syndrome, and a preparation method and application thereof. Background technique [0002] Enteritis, especially ulcerative colitis (UC), is a chronic non-specific inflammatory bowel disease of the rectum and colon whose etiology is not very clear. The lesions are mainly limited to the large intestine mucosa and submucosa. The clinical manifestations are diarrhea, mucus pus and blood in the stool, and abdominal pain. The condition varies from severity to severity, and most of them present a recurring chronic course. Western medicine often uses aminosalicylic acid preparations, glucocorticoids, immunosuppressants, etc. to treat the disease. It has advantages in controlling the symptoms of UC, ...

AI Technical Summary

Problems solved by technology

[0005] Although Guchang Zhixie Pills have a good curative effect, they are pills with rough craftsmanship, low quality standards, slow disintegration, and low bioavailability. Moreover, the drug disintegrates in the stomach, which is irritating to the stomach to a certain extent. Less absorption in the middle and colon, affecting the efficacy of the drug

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