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Preparation method of Chinese herbal compound with natural anti-corrosion effect

A natural anti-corrosion and efficacy technology, which is applied in the field of pharmaceutical preparation, can solve the problems of less active ingredient retention, reduced solvent consumption, and large alcohol consumption, and achieve the effect of good active ingredient retention, reduced solvent use, and convenient extraction operation

Inactive Publication Date: 2014-01-22
LB COSMECEUTICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the problems that the traditional Chinese medicine extract prepared by the traditional preparation process has dark color, few active ingredients, many impurities, cumbersome steps, long production cycle, large energy consumption, large amount of alcohol, etc., according to the diffusion of medicinal materials characteristics, the medicinal materials that are not easily penetrated by solvents are prepared into fine powder suspensions through colloid mills, and the medicinal materials that are easily penetrated by solvents are extracted by circulating percolation, reducing the dissolution of pigments, better retaining small molecules and low boiling point substances, and extracting The process does not produce clogging, greatly reduces the amount of solvent used, and saves the steps of concentration and alcohol precipitation, so as to simplify the process steps, shorten the production cycle, and reduce energy consumption. It has made important contributions to meeting the requirements of cosmetics and saving costs.

Method used

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  • Preparation method of Chinese herbal compound with natural anti-corrosion effect
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Process flow:

[0023] as attached figure 1 The circulating percolation device and process flow shown. The circulation percolation device is connected by percolation tank 1, pump 2, flow meter 3, heating / cooling device 4 and valve 5 to form a circulation device. The medicinal materials that are easily permeated by the solvent are put into the percolation tank 1, and the medicinal materials that are not easily permeated by the solvent are first pulverized with a pulverizer, and then further pulverized into a fine powder suspension together with the solvent with a colloid mill, and then added to the percolation tank 1 Mix with other medicinal materials, and then circulate and extract in percolation tank 1, pump 2 and heating / cooling device 4.

[0024] Antibacterial test steps:

[0025] (1) Test strains

[0026] Staphylococcus aureus (ATCC8739), Escherichia coli (ATCC6538), Pseudomonas aeruginosa (ATCC9027), Candida albicans (ATCC10231), Aspergillus niger (ATCC16404). ...

Embodiment 2

[0052] (1) Grind 50 grams each of tiankuizi and viola chinensis into 20-40 mesh coarse powder with a grinder;

[0053] (2) Add the coarse powder to 1.5L of 40% ethanol solution, and use a colloid mill to grind it into a suspension of 2~50μm fine powder;

[0054] (3) Put 150g of wild chrysanthemum, 150g of honeysuckle, 50g of dandelion, and 50g of Prunella vulgaris into a 2.5L extraction tank, add the fine powder suspension in the previous step to carry out circular extraction, the extraction temperature is 15°C, and the circulation speed is 5L / h, the extraction time is 4h.

[0055] (4) Settling overnight, take the supernatant, filter, add water to 1.5L, and get it.

Embodiment 3

[0057] (1) Grinding the tiankui seeds and Viola chinensis into a coarse powder of 20-40 meshes with a pulverizer;

[0058] (2) Add the coarse powder to 1L of 75% ethanol solution, and use a colloid mill to grind it into a suspension of 2~50μm fine powder;

[0059] (3) Put 150g of wild chrysanthemum, 150g of honeysuckle, 50g of dandelion, and 50g of Prunella vulgaris into a 2.5L extraction tank, add the fine powder suspension in the previous step to carry out circular extraction, the extraction temperature is 0°C, and the circulation speed is 1L / h, the extraction time is 2h.

[0060] (4) Settling overnight, take the supernatant, filter, add water to 1.5L, and get it.

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Abstract

A preparation method of a Chinese herbal compound with a natural anti-corrosion effect comprises the steps as follows: (1), pulverizing muskroot-like semiaquilegia roots and herba violae into coarse powder through a pulverizer; (2), adding a solvent to the coarse powder and grinding the coarse powder into suspension of fine powder through a colloid mill; (3), putting flos chrysanthemi indici, honeysuckle, dandelion and selfheal in an extracting tank, and adding the suspension of the fine powder in the last step for normal temperature circulation extraction; and (4), performing conventional sedimentation and filtration treatment. By means of the preparation method, the problems of low transfer rate of effective constituents, multiple dissolved impurities, dark color, many steps, long operating period, high cost and the like of traditional Chinese medicine preparation technologies can be solved.

Description

technical field [0001] The invention relates to a method for preparing an extract, more specifically, to a method for preparing a traditional Chinese medicine compound with natural antiseptic effect. Background technique [0002] At present, the most commonly used methods for the preparation of traditional Chinese medicine are decoction, concentration, alcohol precipitation, concentration, filtration and other processes. The extract prepared by this method has less low-boiling components, more impurities, and dark color, which affects its appearance in cosmetic products. add using. And the whole process steps are loaded down with trivial details, and the production period is long, and the required equipment is many, and energy consumption is big, and production cost is higher, and alcohol consumption is big. [0003] In order to reduce the dissolution of macromolecular pigments and retain low boiling point components, a cold percolation process is also used. However, the la...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97
Inventor 李成亮袁圆卞春亮
Owner LB COSMECEUTICAL TECH CO LTD
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