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Preparation method of medicine for treating respiratory system infection of livestock and poultry

A respiratory system and drug technology, applied in the direction of respiratory diseases, drug combination, pharmaceutical formula, etc., can solve the problem of incomplete curative effect and achieve the effect of long-lasting drug effect, definite curative effect, and long storage period

Inactive Publication Date: 2013-11-27
SICHUAN DERUNTONG BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The dosage of the injection is accurate and the effect is reliable, unlike the oral medicine that may be affected by digestive juices, food, etc., so that the dose taken cannot fully produce the curative effect

Method used

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  • Preparation method of medicine for treating respiratory system infection of livestock and poultry
  • Preparation method of medicine for treating respiratory system infection of livestock and poultry
  • Preparation method of medicine for treating respiratory system infection of livestock and poultry

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, citric acid 0.2g, procaine hydrochloride 0.05g.

[0033] Preparation:

[0034] Respectively take trimethoprim and citric acid of the prescribed amount, mix them and pulverize them through a flow energy mill, pass through a 120 mesh sieve, and then deliver them in equal amounts with tylosin tartrate, kanamycin sulfate, and procaine hydrochloride. Addition, mixing evenly, inspection of semi-finished products, packaging, packaging, inspection of finished products, that is to say.

Embodiment 2

[0036] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, succinic acid 0.2g, procaine hydrochloride 0.05g.

[0037] Preparation:

[0038] Weigh respectively the prescribed amount of trimethoprim and succinic acid, mix them and pulverize them through a flow energy mill, pass through a 120-mesh sieve, and then add them with tylosin tartrate, kanamycin sulfate, and pain relieving agents in equal amounts. Mix evenly, inspect the semi-finished product, subpackage, pack, inspect the finished product, and put it into storage.

Embodiment 3

[0040] Tylosin tartrate 1g, kanamycin sulfate 1g, trimethoprim 0.2g, citric acid 0.2g, lidocaine hydrochloride 0.05g.

[0041] Preparation:

[0042] Respectively weigh trimethoprim and citric acid in the prescribed amount, mix them, pass through a flow energy mill, pass through a 150-mesh sieve, and then mix them with tylosin tartrate, kanamycin sulfate, and pain relieving agents in equal increments Uniformity, inspection of semi-finished products, sub-packaging, packaging, inspection of finished products, warehousing, and ready to go.

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Abstract

The invention aims at providing a preparation method of a medicine for treating respiratory system infection of livestock and poultry. The medicine has rapid and accurate treatment effects on respiratory system infection and complications of livestock and poultry. The medicine is prepared by the following steps: mixing and crushing 0.2 part of trimethoprim and 0.2 part of a cosolvent, and then sieving the mixture through a 120-mesh sieve or a finer sieve; and uniformly mixing the sieved product with 1 part of tylosin tartrate, 1 part of kanamycin sulfate and 0.05-0.1 part of a pain reliever by a method of progressively increasing by equal quantity, wherein the cosolvent is citric acid, succinic acid or a compound of the two, and the pain reliever is procaine hydrochloride, lidocaine hydrochloride or a compound of the two. The synergism compound tylosin tartrate for livestock injection provided by the invention contains three components, namely the tylosin tartrate, kanamycin sulfate and trimethoprim; the problem that secondary infection cannot be well controlled due to the narrow antibacterial spectrum of the tylosin tartrate when mycoplasma infection is treated can be solved; the problem that the trimethoprim is poorly soluble in water can be solved, a synergism effect of the tylosin tartrate and kanamycin sulfate can be achieved, and the medicine has an obvious treatment effect.

Description

[0001] This application is a divisional application of the invention patent with the application number: 201210277080.6 and the patent name: "Preparation method of compound synergistic tylosin tartrate for veterinary injection". The original filing date: August 6, 2012. technical field [0002] The invention relates to compound synergistic tylosin tartrate for veterinary injection. Background technique [0003] Judging from the current development of my country's animal husbandry industry, the current high incidence of respiratory infections in livestock and poultry, serious complications, and great harm to livestock and poultry. Also do not have comparatively desirable therapeutic drug treating both symptoms and root causes on the market now. Through investigation and research on the domestic and international markets, it is found that the market is in urgent need of a drug that has a stable drug effect, good curative effect, high stability, and is easy to use, and has spec...

Claims

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Application Information

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IPC IPC(8): A61K31/7048A61K9/14A61P31/04A61P29/00A61P11/00A61K31/7036A61K31/505A61K31/167A61K31/245
Inventor 陈益德胡学全周可刚何丽花刘亚
Owner SICHUAN DERUNTONG BIOTECH
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